Techniques for label-free determination of a value of at least one blood property are presented. The techniques may utilize a device that includes an optical objective including at least one lens, at least a first light source situated so as to provide light to a body part at a location that is off-center from a central axis of the objective, at least a first electronic detector situated to receive light gathered by the optical objective and generate image data, at least one electronic processor communicatively coupled to the first electronic detector, the at least one electronic processor configured to determine the value of the at least one blood property based at least in part on the image data, and an output interface communicatively coupled to the at least one electronic processor and configured to provide the value of the at least one blood property.

Disclosed herein include systems, devices, and methods for determining a gating strategy. An acquisition system can cause a particle analyzer to collect parameter measurements of some particles of a sample. An analysis system can receive the parameter measurements and determine a gating strategy from the parameter measurements. The acquisition can collect measurements of some or all of the remaining particles of the sample using the gating strategy determined by the analysis system.

Aspects of the present disclosure include methods for modulating an intensity profile of a laser beam. Methods according to certain embodiments include irradiating an acousto-optic device with a laser to generate an output laser beam having a plurality of angularly deflected laser beams, capturing an image of the output laser beam, determining an intensity profile of the output laser beam along a horizontal axis from the captured image and adjusting one or more parameters of a waveform inputted into the acousto-optic device in response to the determined intensity profile to generate an output laser beam having a modulated intensity profile. Systems having a laser, an acousto-optic device, an imaging sensor and a waveform generator as well as non-transitory computer readable storage medium with instructions for practicing the subject methods are also described.

The invention relates to a new method of determining the presence, absence, number or position(s) of one or more post-translational modifications in a peptide, polypeptide or protein. The invention uses transmembrane pores.

Various embodiments include a scattered light smoke detector comprising: a two-color LED for emitting light of a first wavelength and a second wavelength; a photosensor spectrally matched with said two-color LED; and a control unit connected to the two-color LED and to the photosensor. The control unit is configured to control the two-color LED to emit light of the first wavelength or the second wavelength and to detect a photosensor signal of the photosensor. The control unit is further configured to analyze the photosensor signal for a first scattered radiation intensity and a second scattered radiation intensity allocated respectively to the first wavelength and the second wavelength. There is a polarizer optically connected upstream of the photosensor or downstream of the two-color LED. The polarizer polarizes light passing through at different intensities in dependence upon the respective wavelength of said light.

Various embodiments include a scattered light smoke detector comprising: a two-color LED for emitting light of a first wavelength and a second wavelength; a photosensor spectrally matched with said two-color LED; and a control unit connected to the two-color LED and to the photosensor. The control unit is configured to control the two-color LED to emit light of the first wavelength or the second wavelength and to detect a photosensor signal of the photosensor. The control unit is further configured to analyze the photosensor signal for a first scattered radiation intensity and a second scattered radiation intensity allocated respectively to the first wavelength and the second wavelength. There is a polarizer optically connected upstream of the photosensor or downstream of the two-color LED. The polarizer polarizes light passing through at different intensities in dependence upon the respective wavelength of said light.

A system for the differentiation of plastic and non-plastic particles in suspension in a liquid, and the method of use thereof. The system having a channel for constraining and presenting the liquid to a detector, the detector having at least one transmit electrode for emitting electrical current to at least one receive electrode. Circuitry provides the current input and received electrical signals measurement capacities. Particles passing the receive electrodes alter the received electrical current according to the particle's dielectric properties, the circuitry records the received signals and discerns a particle's nature, most often plastic from non-plastic, from the differential signal of these received signals as a function of frequency.

A portable air quality monitoring device is disclosed that can identify the type of particles in the air. This device takes images of particles in the air and compares them with a library of particles in its memory to identify the type of particles. The device has a housing that draws ambient air into the system and takes microscopic images of the flowing particles and droplets using flash photography. The device can be stand alone or can connect to the back of a mobile phone and use the mobile phone camera and light. People can upload their local air quality data online for all to see the local air quality.

A system and method for sorting sperm is provided. The system includes a housing and a microfluidic system supported by the housing. The system also includes an inlet providing access to the microfluidic system to deliver sperm to the microfluidic system and an outlet providing access to the microfluidic system to harvest sorted sperm from the microfluidic system. The microfluidic system provides a flow path for sperm from the inlet to the outlet and includes at least one channel extending from the inlet to the outlet to allow sperm delivered to the microfluidic system through the inlet to progress along the flow path toward the outlet. The microfluidic system also includes a filter including a first plurality of micropores arranged in the flow path between the inlet and the outlet to cause sperm traveling along the flow path to move against through the filter and gravity to reach the outlet.

A system and method for sorting sperm is provided. The system includes a housing and a microfluidic system supported by the housing. The system also includes an inlet providing access to the microfluidic system to deliver sperm to the microfluidic system and an outlet providing access to the microfluidic system to harvest sorted sperm from the microfluidic system. The microfluidic system provides a flow path for sperm from the inlet to the outlet and includes at least one channel extending from the inlet to the outlet to allow sperm delivered to the microfluidic system through the inlet to progress along the flow path toward the outlet. The microfluidic system also includes a filter including a first plurality of micropores arranged in the flow path between the inlet and the outlet to cause sperm traveling along the flow path to move against through the filter and gravity to reach the outlet.