A method for measuring optical signal detector performance that includes directing light emitted from an optical signal detector onto a first non-fluorescent surface portion in a first detection zone of the optical signal detector. A first characteristic of light detected by a first sensor of the first optical signal detector is measured while the first non-fluorescent surface portion is in the first detection zone of the optical signal detector. Light emitted from the optical signal detector is directed into a first void in the first detection zone of the optical signal detector. A second characteristic of light detected by the first sensor of the optical signal detector is measured while the first void is in the first detection zone of the optical signal detector. And an operational performance status of the optical signal detector is determined based on at least one of the first characteristic and the second characteristic.

A method for measuring optical signal detector performance that includes directing light emitted from an optical signal detector onto a first non-fluorescent surface portion in a first detection zone of the optical signal detector. A first characteristic of light detected by a first sensor of the first optical signal detector is measured while the first non-fluorescent surface portion is in the first detection zone of the optical signal detector. Light emitted from the optical signal detector is directed into a first void in the first detection zone of the optical signal detector. A second characteristic of light detected by the first sensor of the optical signal detector is measured while the first void is in the first detection zone of the optical signal detector. And an operational performance status of the optical signal detector is determined based on at least one of the first characteristic and the second characteristic.

The present disclosure provides an automated sample analyzer having a continuous scanning optical assembly for performing an assay. The optical assembly allows for robust detection of light emitted from a reaction mixture in a dynamically changing environment, such as detection of light from a reaction mixture that is being rotated about an axis at high rotational velocity.

The present invention relates to fluidic devices for preparing, processing, storing, preserving, and/or analyzing samples. In particular, the devices and related systems and methods allow for preparing and/or analyzing samples (e.g., biospecimen samples) by using one or more of capture regions and/or automated analysis.

The present invention provides a plasma treatment detection indicator including a color-changing layer that changes color by plasma treatment, exhibiting excellent heat resistance, with the gasification of the color-changing layer or the scattering of the fine debris of the color-changing layer caused by the plasma treatment being suppressed to the extent that electronic device properties are not affected. Specifically, the present invention provides a plasma treatment detection indicator comprising a color-changing layer that changes color by plasma treatment, the color-changing layer comprising metal oxide fine particles containing at least one element selected from the group consisting of Mo, W, Sn, V, Ce, Te, and Bi, the metal oxide fine particles having a mean particle size of 50 μm or less.

The present application is directed to a multi-sensor gas sampling detection system and method for detecting and measuring the radicals in a radical gas stream and includes at least one radical gas generator in communication with at least one gas source. The radical gas generator may be configured to generate at least one radical gas stream which may be used within a processing chamber. As such, the processing chamber is in fluid communication with the radical gas generator. At least one analysis circuit in fluid communication with the radical gas generator may be used in the detection and measurement system. The analysis may be configured to receive a defined volume and/or flow rate of the radical gas stream. In one embodiment, the analysis circuit may be configured to react at least one reagent with radicals within the defined volume of the radical gas stream thereby forming at least one chemical species within at least one compound stream. At least one sensor module within the analysis circuit may be configured to measure a concentration of the chemical species within the compound stream. One or more flow measurement modules may be in fluid communication with the sensor module. During use, the flow measurement module may be configured to measure the volume of at least one of the compound stream and radical gas stream.

The present invention relates to the use of surfaces that exhibit different surface energies wherein the difference in surface energies is configured to disrupt capillary laminar flow of a fluid travelling between the two surfaces. The invention further relates to the use of such surfaces in assay methods including a device utilising same.

The invention relates to a test set (1) for a photometric measuring device, comprising a mixing container (2) which has a filling opening (3) and comprising a metering container (8) which can be sealingly inserted into the filling opening (3) of the mixing container (2) and which contains a liquid reagent (13) in a closed cavity (9). The cavity (9) has a closure plunger (11), which can be moved axially in the cavity (9), at a first end of the metering container (8), said closure plunger generating a specifiable filling pressure in the reagent (13), and the metering container (8) has a closure membrane (10) at a second metering container and which can be inserted into the mixing container (2). According to the invention, the closure membrane (10) is equipped with a predetermined breaking point (20) which breaks open when the filling pressure is exceeded in a defined manner as a result of an axial movement of the closure plunger (11), said predetermined breaking point (20) of the closure membrane (10) being formed as a linearly extending material taper of the closure membrane (10), wherein the taper is arranged eccentrically in the region of an opening (24) in the base (23) of the substantially cylindrical metering container (8).

The invention relates to a test set (1) for a photometric measuring device, comprising a mixing container (2) which has a filling opening (3) and comprising a metering container (8) which can be sealingly inserted into the filling opening (3) of the mixing container (2) and which contains a liquid reagent (13) in a closed cavity (9). The cavity (9) has a closure plunger (11), which can be moved axially in the cavity (9), at a first end of the metering container (8), said closure plunger generating a specifiable filling pressure in the reagent (13), and the metering container (8) has a closure membrane (10) at a second metering container and which can be inserted into the mixing container (2). According to the invention, the closure membrane (10) is equipped with a predetermined breaking point (20) which breaks open when the filling pressure is exceeded in a defined manner as a result of an axial movement of the closure plunger (11), said predetermined breaking point (20) of the closure membrane (10) being formed as a linearly extending material taper of the closure membrane (10), wherein the taper is arranged eccentrically in the region of an opening (24) in the base (23) of the substantially cylindrical metering container (8).

Methods and systems for the use of a thin-layer spectroelectrochemical cell to detect porphyrins in a wellbore environment are provided. In one embodiment, methods for the use of a thin-layer spectroelectrochemical cell to detect porphyrins in a wellbore environment comprises: positioning a spectroelectrochemical cell in a wellbore penetrating at least a portion of a subterranean formation comprising a downhole fluid; allowing at least a portion of the downhole fluid to flow into the spectroelectrochemical cell; and detecting at least one compound in at least a portion of the downhole fluid, wherein the at least one compound is selected from the group consisting of: a porphyrin, a metalloporphyrin, a porphyrin derivative, a porphyrin-like macrocycle, and any combination thereof.