Patent classifications
G01N24/08
Method For Detecting The Presence Of Abnormal Tissue
A computer implemented method is usable to detect the presence of abnormal tissue through analysis of magnetic resonance relaxation times T1 and T2. The relaxation times T1 and T2 are determined from a data set obtained from a magnetic resonance apparatus. The method includes: loading the data set from at least one tissue into a computing device; determining a region of interest; determining an average value of the free induction decay signal within the region of interest on each of the scans separately; detecting scans with outlier data in each data series; and, if a scan with outlier data is detected, identifying the scan in the data series; determining the relaxation time within the region of interest based on scans from the corresponding data series that are not identified as having outlier data; classifying the tissue as normal or abnormal based on predefined values, which are determined depending on the type of tissue analyzed.
NMR measurements of NMR biomarker GlycA
Biomarkers and/or risk assessments identify patients having an increased risk of certain clinical disease states including, for example, CHD, type 2 diabetes, dementia, or all-cause death (ACD) using NMR signal to measure a level of “GlycA” in arbitrary units or in defined units (e.g., μmol/L) that can be determined using a defined single peak region of proton NMR spectra. The GlycA measurement can be used as an inflammation biomarker for clinical disease states. The NMR signal for GlycA can include a fitting region of signal between about 2.080 ppm and 1.845 ppm of the proton NMR spectra.
NMR measurements of NMR biomarker GlycA
Biomarkers and/or risk assessments identify patients having an increased risk of certain clinical disease states including, for example, CHD, type 2 diabetes, dementia, or all-cause death (ACD) using NMR signal to measure a level of “GlycA” in arbitrary units or in defined units (e.g., μmol/L) that can be determined using a defined single peak region of proton NMR spectra. The GlycA measurement can be used as an inflammation biomarker for clinical disease states. The NMR signal for GlycA can include a fitting region of signal between about 2.080 ppm and 1.845 ppm of the proton NMR spectra.
Method for determining the degree of cure in forages
A method for determining the degree of cure in forages using a nuclear magnetic resonance (NMR) technique. An NMR instrument is used to determine the amount of bound moisture (typically called stem moisture) and free moisture (typically called dew moisture) the degree of which can be used to determine how cured the forage is. This method represents an improvement on the traditional ways of determining how cured a forage is. The traditional ways have been by twisting a bunch of forage in ones hands or using a mechanical method (Hammer of fingernail) to determine if there is too much stem moisture in the stem nodes. The method can be applied using a portable instrument or building the instrument into a forage harvesting machine such as a hay baler.
In situ, real-time in-line detection of filling errors in pharmaceutical product manufacturing using water proton NMR
A method of using the transverse relaxation rate (R.sub.2) of solvent NMR signal to detect filling errors of an alum-containing product in real-time in-line during manufacturing, for example during a fill-finish unit operation. This technique can be used for quality control in vaccine manufacturing to ensure the delivery of the correct concentration of alum-containing product to the product container such as a vial or pre-filled syringe.
EFFICIENT DAMPED PULSED ENERGY TRANSMITTER
A device for generating oscillating signals includes an energy transfer device configured to apply an oscillating signal to a sensitive volume, and a resonant tuning circuit including the energy transfer device. The tuning circuit includes a tuning capacitor configured to cause the tuning circuit to resonate at a selected frequency, and an energy storage device. The transmitting device also includes a controller configured to apply a pulse sequence to the tuning circuit having a series of pulses, the energy storage device configured to retain electrical energy at an end of a first pulse, and discharge the electrical energy to the tuning circuit at an onset of a next pulse of the pulse sequence.
Method and system to analyze geologic formation properties
Systems and methods for determining properties of subterranean formations surrounding a wellbore are provided. An example method can include receiving an image of a formation sample; partitioning the image into a plurality of patches; detecting, via a semantic extraction processor, textures captured in the plurality of patches; associating the textures to a location of the image of the formation sample; reducing a dimension of representation of the textures to obtain one or more vectors, the one or more vectors being based on the textures; and providing a plurality of curves based on the one or more vectors.
Pore contribution corrected quantifying of surface roughness
To separate porosity from surface roughness, length scales for pore size and surface roughness are identified. These length scales are determined from surface roughness measurements and confirmed via NMR pore body calculations and pore size capillary pressure measurements. A filter removes pore contribution to surface roughness measurements and delivers intrinsic surface roughness. Additional filters and methods determine the minimum magnification on which to base surface roughness calculation, based on size of the field of view and where measured surface roughness approaches intrinsic surface roughness as magnification increases but larger magnification increase sampling time and difficulty. Sample irregularities, such as saw marks, are also filtered out or determined to be too large to remove via filter and another area of measurement is located. With the pore corrected quantification of surface roughness, surface relaxivity and pore distribution can be calculated with greater accuracy.
NMR Measurement Unit Fixable Within A Process Channel
The invention relates to an NMR system, and more particularly to an NMR measurement unit including a flow channel for separating a sample from a fluid stream in a process channel, a magnet arranged relative to flow channel for creating a magnetic field in part of flow channel, a coil arranged relative to flow channel for exciting NMR active nuclei of the sample in flow channel and for receiving the frequency pulse that returns to coil from NMR active nuclei, a frame comprising a fastening flange for sealing NMR measurement unit to process channel and a chamber that is closed relative to fluid stream and connected to fastening flange, arranged to be installed mainly inside process channel, within which chamber magnet and coil are arranged and through which chamber the flow channel passes, the frame installable such that flow channel is positioned inside process channel.
EXPERIMENTAL DEVICE AND METHOD FOR SUPERCRITICAL CO2/H2O MIXED FLUID HUFF AND PUFF FOR SHALE OIL DEVELOPMENT
An experimental device and method for supercritical CO.sub.2/H.sub.2O mixed fluid huff and puff for shale oil development includes a CO.sub.2 storage tank, a water vapor generator, a mixing vessel, and a core holder; the CO.sub.2 storage tank and the water vapor generator are in communication with the mixing vessel; a first pressure gauge and a hygronom are connected to an upper end of the mixing vessel, and a displacement pump is connected to a lower end of the mixing vessel; the mixing vessel is connected to an inlet end of the core holder; the core holder is connected to an inlet end of a drying pipe, and the measuring cylinder is disposed upside down in a liquid containing dish, where the liquid containing dish and the measuring cylinder are filled with a saturated sodium carbonate solution.