The present invention provides a method for estimating the molecular complexity of a sample, for example to determine whether biotic or synthetic components are present in the sample. The method comprises the steps of (a) performing one of MS/MS, NMR or IR on a sample; (b) determining the unique peaks in the resulting spectrum; and (c) calculating the molecular assembly index of the sample based on the number of unique peaks in the spectrum.

The present invention provides a method for estimating the molecular complexity of a sample, for example to determine whether biotic or synthetic components are present in the sample. The method comprises the steps of (a) performing one of MS/MS, NMR or IR on a sample; (b) determining the unique peaks in the resulting spectrum; and (c) calculating the molecular assembly index of the sample based on the number of unique peaks in the spectrum.

The present disclosure provides a chemical bond evaluation method capable of directly evaluating the presence or absence of a chemical bond between silica and a silane coupling agent. Included is a chemical bond evaluation method including evaluating the presence or absence of a chemical bond between silica and a silane coupling agent in a rubber composition containing a rubber component, the silica, and the silane coupling agent.

The present disclosure provides a chemical bond evaluation method capable of directly evaluating the presence or absence of a chemical bond between silica and a silane coupling agent. Included is a chemical bond evaluation method including evaluating the presence or absence of a chemical bond between silica and a silane coupling agent in a rubber composition containing a rubber component, the silica, and the silane coupling agent.

The present disclosure provides methods for measuring interactions between a ligand and a protein, comprising hyperpolarizing a ligand in a solvent using para-hydrogen to form a first solution; transferring the first solution to a detector; mixing the first solution with a protein solution, the protein solution having one or more ligands of interest therein; and determining interactions of the hyperpolarized ligand with the one or more ligands of interest by observing a change in an NMR signal of the hyperpolarized ligand. The ligand can include one or more sites for hyperpolarization by parahydrogen, and one or more binding sites for interaction with the protein.

The present disclosure provides methods for measuring interactions between a ligand and a protein, comprising hyperpolarizing a ligand in a solvent using para-hydrogen to form a first solution; transferring the first solution to a detector; mixing the first solution with a protein solution, the protein solution having one or more ligands of interest therein; and determining interactions of the hyperpolarized ligand with the one or more ligands of interest by observing a change in an NMR signal of the hyperpolarized ligand. The ligand can include one or more sites for hyperpolarization by parahydrogen, and one or more binding sites for interaction with the protein.

A method and microfluidic device to perform reservoir simulations using pressure-volume-temperature (“PVT”) analysis of wellbore fluids.

A method includes screening heterogeneity of a rock sample using nuclear magnetic resonance testing to determine a composition of the rock sample, drilling at least one smaller rock sample representative of the determined composition, and testing the at least one smaller rock sample with mercury injection capillary pressure to obtain a capillary pressure distribution of the at least one smaller rock sample. The method further includes decomposing a T.sub.2 distribution from the nuclear magnetic resonance testing and the capillary pressure distribution using Gaussian fitting to identify multiple pore systems, where the small ends of the Gaussian fitted T.sub.2 distribution and the Gaussian fitted capillary pressure distribution are overlapped for at least one of the identified pore systems.

Techniques for determining grain density of a rock sample include identifying an untreated rock sample that includes a solid matrix and a fluid entrained within the solid matrix; measuring, using a gas porosimeter, a grain density of the untreated rock sample; measuring, using nuclear magnetic resonance (NMR), a volume of the fluid entrained within the solid matrix; and determining, based on the measured grain density of the untreated rock sample and the measured volume of the fluid, a grain density of the solid matrix of the untreated rock sample.

The present disclosure provides NMR relaxation methods for characterizing iron carbohydrate drug products. The methods measure .sup.13C and .sup.1H nuclei relaxation parameters such as T1 and PWHH include performing 2D T1 NMR, 1D .sup.13C NMR and .sup.1H NMR to characterize certain physiochemical properties of iron sucrose drug products, for purposes of assessing bioequivalence between a tested iron sucrose product and a comparator product. The disclosure further provides a novel Fe(III)/Fe(II) reduction method using a new reducing agent Na.sub.2S.sub.2O.sub.5 and an .sup.1H NMR method to monitor the Fe(III)/Fe(II) reduction process.