The present invention is directed to devices and methods for monitoring the purity of monomers, adjusting the polymerization conditions, and consequently improving a polymerization reaction process. In one method, monomer purity is estimated using an on-line evaluation by raising the temperature of the monomer formulation having a defined melting point to a first elevated temperature at least 20° C. above a preset melting point for a selected monomer formulation; cooling the monomer formulation at a controlled cooling rate in the range from about 0.5 to 50° C. per minute; measuring at least one critical property selected from the group consisting of a) crystallization peak temperature at the onset of crystallization, b) an area under the crystallization peak, which represents the heat or enthalpy of crystallization, ΔHc and combinations thereof, comparing the at least one of the selected critical properties measures relative to such properties for standard setting monomer formulations.

The present invention is directed to devices and methods for monitoring the purity of monomers, adjusting the polymerization conditions, and consequently improving a polymerization reaction process. In one method, monomer purity is estimated using an on-line evaluation by raising the temperature of the monomer formulation having a defined melting point to a first elevated temperature at least 20° C. above a preset melting point for a selected monomer formulation; cooling the monomer formulation at a controlled cooling rate in the range from about 0.5 to 50° C. per minute; measuring at least one critical property selected from the group consisting of a) crystallization peak temperature at the onset of crystallization, b) an area under the crystallization peak, which represents the heat or enthalpy of crystallization, ΔHc and combinations thereof, comparing the at least one of the selected critical properties measures relative to such properties for standard setting monomer formulations.

Analytic sensors and methods utilize an attenuated total reflection (ATR) crystal to detect volatile compounds in an arrangement that reduces interference from compounds other than the one of interest. In particular, the components in the measurement stream are limited to those having volatilities close to that of the analyte of interest, which may be identified based on, for example, the temperature of the ATR crystal and the “dwell time”—i.e., an interval of substantially constant temperature as the ATR crystal is heated.

A method and apparatus for cleaning a fluid comprising a fluid supply port for receiving a contaminated fluid; a fluid return port for providing a cleaned fluid; an evaporator for evaporating liquid contaminants from the fluid; a fluid line connecting the evaporator between the fluid supply port and the fluid return port; a sensor connected to at least one of the fluid filter, the evaporator, and the fluid line; a controller connected to an output of the sensor, wherein the controller includes: a processor; and a memory device including computer readable instructions which, when executed by the processor cause the processor to perform the steps of: receiving data from the sensor; comparing the data from the sensor to reference data; sending a control signal to at least one of the fluid filter and the evaporator based on comparing the data from the sensor to the reference data.

A method and apparatus for cleaning a fluid comprising a fluid supply port for receiving a contaminated fluid; a fluid return port for providing a cleaned fluid; an evaporator for evaporating liquid contaminants from the fluid; a fluid line connecting the evaporator between the fluid supply port and the fluid return port; a sensor connected to at least one of the fluid filter, the evaporator, and the fluid line; a controller connected to an output of the sensor, wherein the controller includes: a processor; and a memory device including computer readable instructions which, when executed by the processor cause the processor to perform the steps of: receiving data from the sensor; comparing the data from the sensor to reference data; sending a control signal to at least one of the fluid filter and the evaporator based on comparing the data from the sensor to the reference data.

An analyzing device includes a splitting part for causing fluid containing a sample component to flow separately in a first flow passage and a second flow passage; an analyzing column provided on the first flow passage for separating the sample component from the fluid; a first back pressure regulating valve corresponding to a first pressure controlling unit for controlling a pressure in the first flow passage; and a second back pressure regulating valve corresponding to a second pressure controlling unit for controlling a pressure in the second flow passage, wherein flow rate of the fluid in the first flow passage and flow rate of the fluid in the second flow passage are controlled based on a ratio of the pressure in the first flow passage to the pressure in the second flow passage.

An analyzing device includes a splitting part for causing fluid containing a sample component to flow separately in a first flow passage and a second flow passage; an analyzing column provided on the first flow passage for separating the sample component from the fluid; a first back pressure regulating valve corresponding to a first pressure controlling unit for controlling a pressure in the first flow passage; and a second back pressure regulating valve corresponding to a second pressure controlling unit for controlling a pressure in the second flow passage, wherein flow rate of the fluid in the first flow passage and flow rate of the fluid in the second flow passage are controlled based on a ratio of the pressure in the first flow passage to the pressure in the second flow passage.

A non-invasive method to monitor and control of lyophilization of a frozen product solution to remove solvents is disclosed which includes installing one or more wireless pressure sensors configured to fit into a lyophilization vial tray disposed in a lyophilization chamber having a plurality of product vials, wherein the wireless pressure are distributed among the product vials being lyophilized thereby providing spatial pressure variations, collecting the spatial pressure information from said wireless pressure sensors, calculating sublimation rate of the solution, and adjusting pressure and/or temperature within the lyophilization chamber such that the calculated sublimation rate stays within a predetermined envelope.

A non-invasive method to monitor and control of lyophilization of a frozen product solution to remove solvents is disclosed which includes installing one or more wireless pressure sensors configured to fit into a lyophilization vial tray disposed in a lyophilization chamber having a plurality of product vials, wherein the wireless pressure are distributed among the product vials being lyophilized thereby providing spatial pressure variations, collecting the spatial pressure information from said wireless pressure sensors, calculating sublimation rate of the solution, and adjusting pressure and/or temperature within the lyophilization chamber such that the calculated sublimation rate stays within a predetermined envelope.

A device and method for testing a fiber-composite component, which is to be processed by means of bonding, for the presence of at least one substance out of a selection of possible contaminants. A surface heating device for regional heating of a part-zone of the fiber-composite component to be bonded is performed for desorption of contaminants. A sensor array with a plurality of sensors detects contaminants in the gas phase, and a control device ascertains and signals contaminations which are found. An extractor device can be employed to extract machining dust from the fiber-composite component to a desorption device.