G01N27/02

Molecular detection apparatus

A molecular detection apparatus includes a detector. The detector includes: a vibrator having a piezoelectric member that has a first surface and a second surface, a first electrode connected to the first surface, a second electrode connected to the second surface, and a third electrode connected to the second surface and disconnected from the second electrode; a sensitive film overlapping at least one part of the second electrode and at least one part of the third electrode and configured to change a vibration frequency of the vibrator in response to an interaction with target molecules; and a detection electrode to detect the changed vibration frequency.

Method of measuring hematocrit and method of testing blood

A method of measuring hematocrit is provided. The method for measuring hematocrit includes the following steps. A test strip is provided. The test strip includes a reaction region and a pair of electrodes disposed in the reaction region. A whole blood sample is entered to the reaction region. After the whole blood sample enters the reaction region, a plurality of sets of square wave voltages are intermittently applied to the pair of electrodes based on a square wave voltammetry method to obtain a plurality of feedbacks related to hematocrit. An interval between two adjacent sets of square wave voltages ranges from 0.1 seconds to 4 seconds. A feedback of an n-th set of square wave voltages is obtained to calculate a hematocrit value of the whole blood sample and n is a positive integer greater than 1. A hematocrit value is calculated according to the feedback.

Method of measuring hematocrit and method of testing blood

A method of measuring hematocrit is provided. The method for measuring hematocrit includes the following steps. A test strip is provided. The test strip includes a reaction region and a pair of electrodes disposed in the reaction region. A whole blood sample is entered to the reaction region. After the whole blood sample enters the reaction region, a plurality of sets of square wave voltages are intermittently applied to the pair of electrodes based on a square wave voltammetry method to obtain a plurality of feedbacks related to hematocrit. An interval between two adjacent sets of square wave voltages ranges from 0.1 seconds to 4 seconds. A feedback of an n-th set of square wave voltages is obtained to calculate a hematocrit value of the whole blood sample and n is a positive integer greater than 1. A hematocrit value is calculated according to the feedback.

Gas sensing assembly and method

A gas sensing assembly includes a sensing material to be placed in contact with a fluid sample, electrodes coupled with the sensing material that apply an electric field to the sensing material across the electrodes, a heating element that controls a temperature of the sensing material while the sensing material is in contact with the fluid sample, and sensing circuitry to control application of the electric field to the sensing material via the electrodes at an alternating current frequency range in the presence of an uncontrolled ambient temperature and at an elevated alternating current frequency range. The sensing circuitry measures one or more electrical responses of the sensing material responsive to applying the electric field at the alternating current frequency range and at the elevated alternating current frequency range. The sensing circuitry detects presence of a gas in the fluid sample based on the one or more electrical responses.

Automated method to check electrostatic discharge effect on a victim device

Some aspects of this disclosure are directed to an automated method to check electrostatic discharge (ESD) effect on a victim device. For example, some aspects of this disclosure relate to a method, including determining a probe point, in a circuit design, for determining effective resistance between the probe point and ground, where the probe point is on an ESD path of in the circuit design. The method includes determining voltage between the probe point and the ground. The method further includes comparing, by a processing device, a resistance value of the ESD path determined based a predefined electric current value at a source point and the measured voltage with a target resistance value range. The method further includes reporting a violation upon determining that the determined resistance value of the ESD path is outside the target resistance value range.

Point-of-care apparatus and methods for analyte detections using electrochemical impedance or capacitance

The presence of analytes can be detected in the bodily fluid using Electrochemical Impedance Spectroscopy (EIS) or Electrochemical Capacitance Spectroscopy (ECS) in devices, such as handheld point-of-care devices. The devices, as well as systems and methods, utilize using Electrochemical Impedance Spectroscopy (EIS) or Electrochemical Capacitance Spectroscopy (EIS) in combination with an antibody or other target-capturing molecule on a working electrode. Imaginary impedance or phase shift, as well as background subtraction, also may be utilized.

Device for determining the moisture and/or the conductivity of a medium
11561189 · 2023-01-24 · ·

The invention includes a device for determining the moisture or conductivity of a medium in a container. A measurement probe is plunged into the medium and consists of a conductive material, a conductive rod, and a first feed-through component designed such that the conductive rod can be fastened to an electrically conductive wall or holder. A rod of a non-conductive material and a second feed-through component are provided, where the non-conductive rod can be fastened to the wall, the conductive rod and the non-conductive rod are dimensioned and oriented that the measurement probe is oriented parallel to the longitudinal axis of the container and a signal-processing unit designed such that high-frequency measurement signals are conducted via the measurement line to the measurement probe and that the moisture or the conductivity of the medium is determined by means of a TDR method.

Methods and systems for measuring gaps between exterior structures and interior structures
11561078 · 2023-01-24 · ·

Disclosed herein is a method of measuring a gap between exterior structures and interior structures. The method comprises directing a transmitted m-wave signal from an exterior surface of the exterior structure into the exterior structure and the interior structure. The transmitted m-wave signal is generated by a gap sensing device that comprises an electromagnetic dual-tuned resonant coil sensor. The method also comprises measuring a received m-wave signal with the gap sensing device. The received m-wave signal comprises the transmitted m-wave signal influenced by the assembly. The method further comprises determining a size of the gap between the exterior structure and the interior structure based at least partially on at least one measured characteristic of the received m-wave signal.

BIOSENSOR FOR DETECTION OF SARS-COV-2 SPIKE GLYCOPROTEIN AND RELATED METHODS
20230017081 · 2023-01-19 ·

An example biosensor includes a substrate, a graphene layer disposed on the substrate, and a binding site bonded to the graphene. The binding site includes an antibody configured to bind a SARS-CoV-2 spike glycoprotein.

APPARATUS AND METHOD FOR ANALYZING IN VIVO COMPONENT AND IMPEDANCE MEASURING APPARATUS

An apparatus for analyzing an in vivo component is provided. The apparatus for analyzing an in vivo component may include an impedance sensor including a first electrode and a second electrode configured to contact a fluid channel of a fluid to be analyzed. The apparatus may include an impedance measurement device configured to apply a current to the first electrode and the second electrode, measure a voltage between the first electrode and the second electrode based on applying the current, and measure an impedance of the fluid based on the measured voltage. The apparatus may include a processor configured to model the measured impedance using an equivalent circuit; and analyze the in vivo component based on modeling the measured impedance using the equivalent circuit.