A TLC plate allows the separation and detection of target substances on one plate. The TLC plate is made up of a substrate, a separating medium layer stacked on the substrate, and a permeation layer discontinuously stacked on the separating medium layer and allows the permeation of a target substance separated in the separating medium layer, wherein the separating medium layer has a separating property for the target substance and an optical responsiveness for ultraviolet rays, and the permeation layer has an optical responsiveness different from that of the separating medium layer.

A paper-based micro fluidic device suitable for electrokinetics and particularly isotachophoresis (ITP) and a kit comprising same is provided. Further, a method for the preparation of said paper-based micro fluidic device and a method of use thereof for the detection and/or separation of molecules of interest are provided.

A modulator for simply providing fast and precise sampling of a chromatographic peak eluting from a first column into a second column of a comprehensive two-dimensional gas chromatograph, where the modulator includes a planar component containing a first gas passage for connecting a carrier gas source to the second separation column, a second gas passage for connecting the first separation column to an exhaust outlet, a connecting gas passage between the first and second gas passages, and two individually controllable open/close valves arranged in parallel connection in the first gas passage between its connection to the carrier gas source and the branch-off of the connecting gas passage, and where the gas passages and valves are formed in the planar component by micromachining.

Provided is a plate-type column which allows the temperature of its inner passage to be rapidly increased or decreased while ensuring the correctness of an analysis or other operations. A plate-type column 10 includes: a plate-shaped main body 11; projecting portions 12 and 13 protruding from a circumferential edge of the main body 11; and a fluid-flow passage 14 extending in the main body 11 and the projecting portions 12 and 13. An intermediate portion of the passage 14 is provided in the main body 11, while each of the end portions of the passage 14 extends from the main body 11 through the projecting portion 12 or 13, with each of the end portions being open to the outside at the tip of the projecting portion 12 or 13.

Provided is a plate-type column which allows the temperature of its inner passage to be rapidly increased or decreased while ensuring the correctness of an analysis or other operations. A plate-type column 10 includes: a plate-shaped main body 11; projecting portions 12 and 13 protruding from a circumferential edge of the main body 11; and a fluid-flow passage 14 extending in the main body 11 and the projecting portions 12 and 13. An intermediate portion of the passage 14 is provided in the main body 11, while each of the end portions of the passage 14 extends from the main body 11 through the projecting portion 12 or 13, with each of the end portions being open to the outside at the tip of the projecting portion 12 or 13.

Chromatography plate for the separation and detection of ion selective ligands and their complexes. The combination of an enhanced chromatographic separation process with an ultraviolet imaging device for detection is developed for selective and simultaneous multiple ion sensing. The method involves the fabrication of microfluidic channels on a porous chromatographic substrate to enhance separation of ligands containing ultraviolet chromophores and their complexes with ions of interest. The chromatographic plate is analyzed under an ultraviolet imaging device to quantify the concentration of the different ions present in a sample.

Chromatography plate for the separation and detection of ion selective ligands and their complexes. The combination of an enhanced chromatographic separation process with an ultraviolet imaging device for detection is developed for selective and simultaneous multiple ion sensing. The method involves the fabrication of microfluidic channels on a porous chromatographic substrate to enhance separation of ligands containing ultraviolet chromophores and their complexes with ions of interest. The chromatographic plate is analyzed under an ultraviolet imaging device to quantify the concentration of the different ions present in a sample.

The invention relates to cartridges for thin layer chromatography (TLC) which hermetically seal the TLC mobile phase during loading, performance of the TLC process, and analysis of the chromatogram. It further relates to associated methods of usefor example for detecting or quantifying an analyte in a sample. It further relates to processes for assembling the cartridge, to associated equipment adapted for use with them, and kits of parts.

The invention relates to cartridges for thin layer chromatography (TLC) which hermetically seal the TLC mobile phase during loading, performance of the TLC process, and analysis of the chromatogram. It further relates to associated methods of usefor example for detecting or quantifying an analyte in a sample. It further relates to processes for assembling the cartridge, to associated equipment adapted for use with them, and kits of parts.

The present invention relates to simple, low-cost, rapid paper-based diagnostic devices and their methods of use.