A laboratory system and a method for separating interfering substances contained in test samples is presented. The laboratory system comprises separation vessels comprising solid surfaces and capturing molecules which are immobilized on the solid surfaces. The capturing molecules of the separation vessels are configured to bind interfering substances of laboratory tests of different analytical methods.

A reaction analysis system includes a first flow path through which a reaction fluid, obtained by mixing reactants in a mixer, flows, a second flow path through which the reaction fluid flows and that has higher heat exchange efficiency than the first flow path, a temperature measurer that measures a temperature distribution of the reaction fluid along the first flow path, and a reaction analysis device that specifies a reaction state of the reaction fluid based on a reaction parameter. The reaction parameter is obtained from the measured temperature distribution and indicates the reaction state of the reaction fluid.

In some aspects, automated rapid antimicrobial susceptibility testing systems for performing a multi-assay testing sequence can include an automated incubation assembly having a nest assembly adapted to house at least one test panel having a plurality of wells for receiving a sample comprising microorganisms originating from a clinical sample, the incubation assembly facilitating incubation of one or more test panels in order to undergo the multi-assay testing sequence; a robotic handling assembly configured to accept one or more incoming test panels and move them to and from the incubation assembly for incubation between each assay of the multi-assay testing sequence; an automated liquid handling assembly configured to exchange one or more fluids in the plurality of wells of the test panels; and an optical assembly for interrogation and readout of each assay of the multi-assay testing sequence being performed in the plurality of wells.

The invention includes sample preparation cartridges and apparatuses. The invention provides means for lysing and optionally selectively capturing at least one compound in a sample to purify, concentrate, and/or select for the at least one compound. The invention can be used in conjunction with a sample processing instrument to create a fully-automated or near-fully-automated sample workflow.

Automated test instruments electronically determine and/or obtain cell availability of cells of a holding structure in an incubated test chamber and for each of a plurality of open and available cells and electronically identify neighboring cells, electronically determining whether each of the identified neighboring cells are occupied or empty and, if occupied, electronically evaluating at least one of a test status or a time from load of a specimen container held therein. The instruments then electronically rank each of the plurality of open and available cells based at least in part on whether the identified neighboring cells are occupied or empty and the at least one of test status or time from load of the occupied cells of the identified neighboring cells. The loading mechanism is then directed to load an incoming specimen container into a selected one of the open and available cells based on the ranking.

A liquid distribution method comprises: providing at least two ferrying units, each ferrying unit made to reciprocate between an initial workstation and a first workstation; transferring from the initial workstation onto each ferry unit a reactor containing a sample; at the first workstation, adding a reagent into the reactor; recording, as a first cycle, a shortest time window during which a sequence of actions performed by each ferry unit can be cyclically reproduced, and recording, as a second cycle, a quotient obtained by dividing the first cycle by the number of ferry unit, and successively transferring the reactors to other ferry units staggeredly at intervals of the second cycle; and sequentially removing from the ferry units the reactors for which the mixing has been completed, staggeredly at intervals of the second cycle, and placing another reactor containing the sample onto the ferry unit from which the reactor was removed.

An intelligent experimental device for collaborative mining of associated resources includes a signal transmission mechanism, a pressure maintaining mechanism, a feeding mechanism, and a reaction mechanism. The signal transmission mechanism includes a centralized controller, an annunciator, signal receivers, a power supply, a power cord, signal transmitters, and signal sensing valves. The pressure maintaining mechanism includes ambient and axial pressure oil chambers, ambient and axial pressure pumps, ambient and axial pressure liquid distribution tanks, a comprehensive pressure distribution pipe, and hydraulic transmission pipes. The feeding mechanism includes monitoring analyzers, temperature controllers, solution transfer pipes, seepage pumps, mixture conveying pipes, a comprehensive liquid distributor, an aggregate chamber, a liquid chamber, an oil chamber, a gas chamber, a mixing chamber and an analytical purifier. The reaction mechanism includes a uranium mine cavity, a coal seam cavity, an oil-gas cavity, nuclear magnets, thermohydraulic sensors, and shearing gaskets.

Systems and methods for continuous flow polymerase chain reaction (PCR) are provided. The system comprises an injector, a mixer, a coalescer, a droplet generator, a detector, a digital PCR system, and a controller. The injector takes in a sample, partitions the sample into sample aliquots with the help of an immiscible oil phase, dispenses waste, and sends the sample aliquot to the mixer. The mixer mixes the sample aliquot with a PCR master mix and diluting water, dispenses waste, and sends the sample mixture (separated by an immiscible oil) to the coalescer. The coalescer coalesces the sample mixture with primers dispensed from a cassette, dispenses waste, and sends the reaction mixture (separated by an immiscible oil) to the droplet generator. The droplet generator converts the sample mixture into an emulsion where aqueous droplets of the reaction mixture are maintained inside of an immiscible oil phase and dispenses droplets to the digital PCR system. The digital PCR system amplifies target DNAs in the droplets. The detector detects target DNAs in the droplets. The controller controls the system to run automatically and continuously.

A purpose is to provide a monitoring system to monitor whether there is a substance to be monitored in the air, and a detecting device used in the monitoring system. The monitoring system includes a detecting device, an analyzing device, and an abnormality notification system. The detecting device determines whether the air is in an abnormal state on the basis of an output signal from an abnormality detection sensor, pours liquid to be inspected, into which the air is sucked and liquefied, into a previously-installed reagent container when determining the abnormal state, generates mixed liquid in which a reactant in the reagent container and the poured liquid to be inspected are mixed, and drops the generated mixed liquid to an electrode of the analyzing device. The analyzing device determines existence/non-existence of a substance to be monitored on the basis of the mixed liquid dropped to the electrode, and gives a predetermined notification to the abnormality notification system when determining that there is the substance to be monitored. The abnormality notification system gives a predetermined notification when receiving the notification from the analyzing device.

Included are: a main body including an installation part in which a cartridge housing a liquid for treating a test substance contained in a specimen is installed and a detector configured to detect the test substance treated with the liquid within the cartridge installed in the installation part; a lid part arranged rotatably on the main body about a shaft so as to open and close the installation part; a biasing part biasing the lid part in an opening direction; and a plurality of regulators each generating resistance against a biasing force in the opening direction at different timing during an opening motion of the lid part.