The tunnel lining surface inspection system capable of measuring the three dimensional shape of the surface of the tunnel lining surface to precisely determine whether cracking has a risk of leading to flaking, by the light section method using the photography means and the slit laser beam projecting means, mounted in the vehicle, while the vehicle is traveling in the tunnel, and the vehicle used in the system are proposed. Image processing is performed to obtain the image used for inspecting the tunnel lining surface, by using the result of the three dimensional shape measurement of one side face of the tunnel lining surface, measured while the photography means/slit laser beam projecting means arrangement means is fixed to the first measurement position, and the result of the three dimensional shape measurement of the other side face of the tunnel lining surface, measured while the photography means/slit laser beam projecting means arrangement means is fixed to the second measurement position.

A structure of interest (T) is irradiated with radiation for example in the x-ray or EUV waveband, and scattered radiation is detected by a detector (19, 274, 908, 1012). A processor (PU) calculates a property such as linewidth (CD) or overlay (OV), for example by simulating (S16) interaction of radiation with a structure and comparing (S17) the simulated interaction with the detected radiation. The method is modified (S14a, S15a, S19a) to take account of changes in the structure which are caused by the inspection radiation. These changes may be for example shrinkage of the material, or changes in its optical characteristics. The changes may be caused by inspection radiation in the current observation or in a previous observation.

To provide a concentration measurement method with which the concentrations of predetermined chemical components can be measured non-destructively, accurately, and rapidly by a simple means, up to the concentrations in trace amount ranges, as well as a concentration measurement method with which the concentrations of chemical components in a measurement target can be accurately and rapidly measured in real time up to the concentrations in nano-order trace amount ranges, and which is endowed with a versatility that can be realized in a variety of embodiments and modes. In the present invention, a measurement target is irradiated, in a time sharing manner, with light of a first wavelength and light of a second wavelength that have different optical absorption rates with respect to the measurement target. The light of each wavelength, arriving optically via the measurement target as a result of irradiation with the light of each wavelength, is received at a shared light-receiving sensor. A differential signal is formed, the differential signal being of a signal pertaining to the light of the first wavelength and a signal pertaining to the light of the second wavelength, the signals outputted from the light-receiving sensor upon receipt of the light. The concentration of a chemical component in the measurement target is derived on the basis of the differential signal.

A method is provided comprising, obtaining an infrared (IR) spectrum of a Peripheral Blood Mononuclear Cells (PBMC) sample of a subject by analyzing the sample by infrared spectroscopy; analyzing the infrared spectrum using a processor (22), and based on the analyzing using the processor, using an output device (24), generating an output indicative of the presence of a benign tumor of the subject. Other applications are also described.

Provided is a sample-analyzing system used for identifying a target sample from its measurement data obtained using a plurality of analyzing devices including at least one device selected from a fluorescent X-ray analyzer, atomic absorption photometer and inductively coupled plasma emission analyzer as well as at least one device selected from an infrared spectrophotometer and Raman spectrophotometer. The system includes: a storage section for holding measurement data obtained for each of the reference objects using the analyzing devices; a measurement data comparator for comparing, for each analyzing device, the measurement data of the target sample with those of the reference objects and for determining the degree of matching of the target sample with each reference object; an integrated degree-of-matching calculator for calculating an integrated degree of matching from the degrees of matching determined for the analyzing devices; and a comparison result output section for outputting information concerning a predetermined number of reference objects in descending order of the integrated degree of matching.

To carry out evaluation of a road surface property easily and in a short period of time without being costly. Measurement data of a road surface measured for a predetermined road width along a path of a road to be measured is acquired; a unit area having a preset length dimension along the path in the road width is set along the path; a model plane in the unit area is set based on the measurement data at each point in the unit area; point group data is generated from a spaced amount of the model plane and each point in the unit area, visualize and display the spaced amount in the path, and display a result of evaluation obtained through statistical processing with the path shown on a map.

A system and method for optical tomography including illuminating an object with pulsing stimulus light and pulsing the stimulus light at a repetition frequency having a pulse period that is greater than a dead-time of a detector. Coordinating the pulse with the dead-time of the detector allows for higher powered light source and improves early photon detection.

A system for processing Raman scattering light from a sample is provided. The system includes a source, a digital mirror device (DMD), a detector, and an analyzer. The DMD is configured to reflect Raman scattering light and includes micromirrors selectively controllable between ON and OFF states. The detector is configured to detect Raman scattering light and to produce signals representative of the Raman scattering light. The analyzer is in communication with the light source, the DMD, the detector, and a memory storing instructions, which instructions when executed cause the processor to: a) control the light source to produce a beam of light for interrogating the sample; b) control the DMD to place in an ON or OFF state based on one or more known spectral shapes stored in the memory; and c) process the Raman scattering light reflected by the micromirrors in the ON state.

A method for determining a refractive power of a large-surface-area transparent object, such as a windshield, a visual aid, a cockpit glazing, a helmet visor, or the like, includes detecting a first imaging of a first line grating through the transparent object at at least one predetermined point of the object using a camera and determining a line spacing of the first imaging, the rotation of the lines relative to the first line grating or both through use of a computing unit on the basis of the first imaging at the at least one specified point and using the line spacing or rotation of lines to determine the refractive power at the at least one predetermined point of the transparent object.

The present invention relates to methods for detecting the chromatin state of a cell based on recording a super resolution image of nucleosome organization and correlating said imaged with size of nucleosomal clutches, nucleosomal density and/or number of nucleosomes per nucleosomal clutches. Additionally, the invention relates to a kit comprising a first antibody capable of specifically binding to a histone protein and a photoswitchable fluorophore linked-secondary antibody and the use of the kit of the invention for detecting the chromatin state of a cell and isolating a cell in an open chromatin state or in a closed chromatin state. The invention also relates to a device adapted to detect the chromatin state of a cell.