A pulsed magnetic particle imaging system includes a magnetic field generating system that includes at least one magnet, the magnetic field generating system providing a spatially structured magnetic field within an observation region of the magnetic particle imaging system such that the spatially structured magnetic field will have a field-free region (FFR) for an object under observation having a magnetic nanoparticle tracer distribution therein. The pulsed magnetic particle imaging system also includes a pulsed excitation system arranged proximate the observation region, the pulsed excitation system includes an electromagnet and a pulse sequence generator electrically connected to the electromagnet to provide an excitation waveform to the electromagnet, wherein the electromagnet when provided with the excitation waveform generates an excitation magnetic field within the observation region to induce an excitation signal therefrom by at least one of shifting a location or condition of the FFR. The pulsed magnetic particle imaging system further includes a detection system arranged proximate the observation region, the detection system being configured to detect the excitation signal to provide a detection signal. The excitation waveform includes a transient portion and a substantially constant portion.

The invention relates to a method and apparatus for detecting superparamagnetic material. The method comprises applying, by an excitation coil, a magnetic field during a first period to an object to modulate a magnetization of the superparamagnetic material, the magnetic field comprising a first component with a first frequency; positioning a sensing device at a first position from the excitation coil receiving a first signal by a first detection sub-coil in the sensing device and a second signal by a second detection-sub-coil in the sensing device; determining a sensor signal from the first signal and the second signal; determining a detection signal based on the sensor signal; determining a parameter indicating an amount of superparamagnetic material by dividing the detection signal by the first signal, and repeating steps to at at least one different position in order to determine a location where the parameter has a maximal value.

An electronic device is provided. The electronic device includes a magnetic sensor, an acceleration sensor, and a processor operatively connected to the magnetic sensor and the acceleration sensor, wherein the processor is configured to acquire multiple pieces of first magnetic data by using the magnetic sensor in a first area where the electronic device is located, generate a virtual marker corresponding to the first area by using the multiple pieces of first magnetic data, determine the movement of the electronic device on the basis of multiple pieces of first acceleration data in a first direction, the data being acquired by using the acceleration sensor, determine the posture of the electronic device on the basis of multiple pieces of second acceleration data in a second direction that is perpendicular to the first direction, the data being acquired by using the acceleration sensor, and determine, on the basis of at least one of the movement of the electronic device and the posture of the electronic device, multiple pieces of third magnetic data to be used for comparison with the virtual marker, among multiple pieces of second magnetic data acquired within a designated radius with reference to the first area by using the magnetic sensor.

An electronic device is provided. The electronic device includes a magnetic sensor, an acceleration sensor, and a processor operatively connected to the magnetic sensor and the acceleration sensor, wherein the processor is configured to acquire multiple pieces of first magnetic data by using the magnetic sensor in a first area where the electronic device is located, generate a virtual marker corresponding to the first area by using the multiple pieces of first magnetic data, determine the movement of the electronic device on the basis of multiple pieces of first acceleration data in a first direction, the data being acquired by using the acceleration sensor, determine the posture of the electronic device on the basis of multiple pieces of second acceleration data in a second direction that is perpendicular to the first direction, the data being acquired by using the acceleration sensor, and determine, on the basis of at least one of the movement of the electronic device and the posture of the electronic device, multiple pieces of third magnetic data to be used for comparison with the virtual marker, among multiple pieces of second magnetic data acquired within a designated radius with reference to the first area by using the magnetic sensor.

A hysteresis effect-based Field Free Point-Magnetic Particle Imaging (FFP-MPI) method includes the following steps: acquiring a hysteresis loop model of Superparamagnetic Iron Oxide Nanoparticles (SPIOs); calculating to obtain a Point Spread Function (PSF) of the SPIOs on the basis of a sinusoidal excitation magnetic field and the hysteresis loop model of the SPIOs; acquiring an original reconstructed image of FFP-MPI on the basis an FFP moving track and a voltage signal; performing deconvolution on the original image with respect to the PSF considering an hysteresis effect, so as to obtain a final reconstructed image; the artifacts and phase errors of image reconstruction caused by the hysteresis effect of the SPIOs with large particle sizes are reduced, the deficiency in reconstruction by the traditional reconstruction method that ignores the hysteresis effect is overcome, the reconstruction speed and the resolution are greatly improved, and the application range of the SPIOs is expanded.

A generation, enhancement, and absorption system for the acquisition of energy from a predetermined chosen environment. The generation, enhancement, absorption system absorbs energy through a process whereby magnetic/electrical fields interact and interlace to create, develop, and support a platform magnetic/electrical energy field that assists and supports in the acquisition of energy from an environment to the generation, enhancement, and absorption system. Coils are used to create magnetic/electrical fields. Ions are placed with the particles in the space surrounding within and without the generation, enhancement, and absorption system. The method of interacting and interlacing of fields creates a platform magnetic/electrical field that moves in a particular direction. The platform magnetic/electrical field starts to access an environmental energy field. The platform magnetic/electrical energy field acquires energy from the environment and transfers to the Magnetic Field Generation with Particle Enhancement with Charge-based Absorption system.

The present disclosure provides an apparatus for obtaining image information on a target using magnetic particle imaging (MPI), the apparatus including: a magnetic field generating means including a first magnetic member and a second magnetic member; and at least one processor operably connected to the magnetic field generating means, wherein the at least one processor is configured to cause the magnetic field generating means to form magnetic fields in an ambient space of the target according to a predetermined rule, determine, as a field free line (FFL), a position corresponding to a point, a line, or a plane at which strength of the magnetic fields in the ambient space is less than a threshold value, provide a first control command for the magnetic field generating means such that the field free line moves along a predetermined path, identify the field free line changed in response to movement of the magnetic field generating means according to the first control command, and generate the image information on the target on the basis of the field free line changed, and the magnetic fields generated from the first magnetic member and the second magnetic member are asymmetric with respect to the target.

Disclosed herein are an apparatus and method for imaging nano magnetic particles. The apparatus may include a measurement head in which a through hole for accommodating a sample including nano magnetic particles is formed and in which an excitation coil and a detection coil are installed, a field-free region generation unit for forming a field-free region, in which there are few or no magnetic fields, in a spacing area between the identical magnetic poles that face each other, and a control unit for applying a signal to the excitation coil when the measurement head is located inside the spacing area of the field-free region generation unit, controlling the field-free region so as to move in the sample, and imaging the 3D positional distribution of the nano magnetic particles included in the sample based on a detection signal output from the detection coil.

A magnetic field analysis device includes a magnetization application unit that divides a virtual space into a plurality of volume elements and applies magnetization to each of the volume elements, and a magnetic field calculation unit that calculates, on each of a plurality of observation points in the virtual space, based on the magnetization applied to a plurality of the volume elements around the observation point, a magnetic field generated at the observation point for each volume element and obtains a magnetic field generated at each of the plurality of the observation points based on a calculation result of each of the plurality of the volume elements.

A magnetic field analysis device includes a magnetization application unit that divides a virtual space into a plurality of volume elements and applies magnetization to each of the volume elements, and a magnetic field calculation unit that calculates, on each of a plurality of observation points in the virtual space, based on the magnetization applied to a plurality of the volume elements around the observation point, a magnetic field generated at the observation point for each volume element and obtains a magnetic field generated at each of the plurality of the observation points based on a calculation result of each of the plurality of the volume elements.