An apparatus for performing diffuse optical imaging of a patient, said apparatus comprising: a computer; at least one sensor module comprising at least one optical source, at least one photodetector, and calibration data specific to said at least one sensor module; means for communicating between said computer and said at least one sensor module; means for automatically accessing said calibration data; and means for adjusting said apparatus in order to produce calibrated measurements.

The present technology is directed to barium-133 (“Ba-133”) based standards that simulate expected energy emissions of iodine-131 (“I-131”), and thus can be used to calibrate radioactivity measuring instruments (e.g., dose calibrators) used to measure the radioactivity of I-131 drug products. The Ba-133 standards can be manufactured in geometries typical of those used to administer I-131 drug products, including, for example, as a capsule, a syringe, a vial, etc.

The present disclosure relates to methods and systems for calibrating an X-ray apparatus. The X-ray apparatus may include an X-ray detector and a collimator. To calibrate the X-ray apparatus, the methods and systems may include moving the X-ray detector from a first position to a second position along a first axis of a coordinate system, wherein the first position is under a scanning table, and the second position is outside the scanning table; moving the collimator to align the collimator with the X-ray detector at the second position; determining one or more parameters; and determining a second value of the first encoder when the collimator is aligned with the X-ray detector at the first position based on the one or more parameters.

An instrument and software methodology to detect a radioactive source and incorporates the following: 1) two radiation detectors in a co-axial configuration, housed in a handheld probe, and 2) a gamma detection control unit executing software algorithms to limit the functional field of view to the front aspect of the probe, vary the depth and width of the field of view to provide collimation without the use of metallic shielding, and allowing the instrument to measure the distance to the radiation source.

A method and system for calibrating a PET scanner are described. The PET scanner may have a field of view (FOV) and multiple detector rings. A detector ring may have multiple detector units. A line of response (LOR) connecting a first detector unit and a second detector unit of the PET scanner may be determined. The LOR may correlate to coincidence events resulting from annihilation of positrons emitted by a radiation source. A first time of flight (TOF) of the LOR may be calculated based on the coincidence events. The position of the radiation source may be determined. A second TOF of the LOR may be calculated based on the position of the radiation source. A time offset may be calculated based on the first TOF and the second TOF. The first detector unit and the second detector unit may be calibrated based on the time offset.

Gamma ray detection system (10) comprising a computation system including a signal processing and control system (30), a detection module assembly (13) including at least one detection module (14) configured for detecting gamma ray emissions from a target zone (4), each detection module comprising at least one scintillator plate (16) having a major surface (40a) oriented to generally face the target zone and lateral minor surfaces (40b) defining edges of the scintillator layer, and a plurality of photon detectors oupled to said at least one scintillator plate and connected to the signal processing and control system. The scintillator plate comprises a material having isotopes intrinsically emitting radiation causing intrinsic scintillation events in one or more scintillator plates having an intensity measurable by the photon detectors. The gamma ray detection system comprises a calibration module configured to execute a spatial calibration procedure based on measurements of a plurality of said intrinsic scintillation events output (37) by the photon detectors, the spatial calibration procedure for determining spatial positions of scintillating events in the scintillator plate as a function of the outputs of the photon detectors.

The specification discloses methods of adjusting calibration data in an X-ray inspection system. Calibration data is initially generated. X-ray scan images of a cargo container are then acquired. Each of the X-ray scan images are segmented into regions of interest, where the regions of interest volumetrically encompass a known material or a material corresponding to a known HS code. Using the calibration data, first data indicative of Zeff of each of the regions of interest are determined. The first data is compared with second data indicative of known Zeff corresponding to the known materials and/or HS codes. The calibration data is then adjusted to generate a second calibration data if the first and second data differ significantly. The calibration data is replaced by the second calibration data in the memory.

The disclosure relates to a system and method for evaluating and calibrating detector in a scanner, further evaluating and calibrating time information detected by at least one time-to-digital convertor.

A method and a system for a two-step calibration method for the polychromatic semiconductor-based PCD forward counting model, to account for various pixel summing readout modes for imaging at different resolutions. The flux independent weighted bin response function is estimated using the expectation maximization method, and then used to estimate the pileup correction terms at plural tube voltage settings for each detector pixel. To correct the variation of the detector response due to different PCD sub-pixel summing schemes, the embodiments calibrate forward model parameters based on the various pixel readout modes.

The invention provides a sensitivity correction coefficient calculating system for an X-ray detector with which the sensitivity correction coefficient can be calculated using a multipurpose X-ray source instead of a specific X-ray source. In the sensitivity correction coefficient calculating system for an X-ray detector having a detection surface where detection elements for detection the X-ray intensity are aligned one-dimensionally or two-dimensionally, fitting is carried out on the measured X-ray intensity detected by a detection element using an approximation function so as to calculate the sensitivity correction coefficient using the calculated X-ray intensity calculated from the approximation function and the measured X-ray intensity.