Embodiments disclose a device for testing biological specimen. The device includes a sample carrier and a detachable cover. The sample carrier includes a specimen holding area. The detachable cover is placed on top of the specimen holding area. The detachable cover includes a magnifying component configured to align with the specimen holding area. The focal length of the magnifying component is from 0.1 mm to 8.5 mm. The magnifying component has a linear magnification ratio of at least 1. Some embodiments further include a multi-camera configuration. These embodiments include a first camera module and a second camera module arranged to capture one or more images of the first holding area and the second holding area, respectively. The processor may perform different analytic processes on the captured images of different holding areas to determine an outcome with regard to the biological specimen.

A method for 3D recording of data on a medium formed from a transparent photosensitive material including at least one dopant. The method includes a first step of calibrating and checking a pulsed light source including calibrating the number of pulses, the level of fluence of each pulse emitted and the rate of the pulses and a step of inscribing an area of the material. The fluence of each pulse emitted, the number of pulses and the rate of the pulses are suitable for irradiating the material in the area so as to form fluorescent clusters stabilized from the dopant while minimizing the modification of the refractive index and the absorption coefficient of the medium in a wavelength range from visible to near infrared.

A method for 3D recording of data on a medium formed from a transparent photosensitive material including at least one dopant. The method includes a first step of calibrating and checking a pulsed light source including calibrating the number of pulses, the level of fluence of each pulse emitted and the rate of the pulses and a step of inscribing an area of the material. The fluence of each pulse emitted, the number of pulses and the rate of the pulses are suitable for irradiating the material in the area so as to form fluorescent clusters stabilized from the dopant while minimizing the modification of the refractive index and the absorption coefficient of the medium in a wavelength range from visible to near infrared.

A preparation includes an image sensor, a package, and a transparent plate. The image sensor has an imaging area on a front surface. The package is electrically connected to the image sensor. The transparent plate opposes the front surface of the image sensor with a mounting medium interposed therebetween. On the surface of the transparent plate, first and second grooves are formed. The image sensor is disposed between the first and second grooves.

An image acquisition device includes a cassette mounting unit in which a cassette is detachably mounted, the cassette holding the slide glasses in a plurality of stages in a predetermined arrangement direction, a light source that emits inspection light toward the cassette, a scanning unit that performs scanning with the inspection light in the arrangement direction, a light reflection unit that is disposed on the back surface side of the cassette and reflects the inspection light emitted from the light source, a light detection unit that detects reflected light including the inspection light reflected by at least one of the light reflection unit, the cassette, and the slide glass, and outputs a detection signal, and an information generation unit that generates holding information on a holding position and/or a holding state of the slide glass held in the cassette on the basis of the detection signal.

An image acquisition device includes a cassette mounting unit in which a cassette is detachably mounted, the cassette holding the slide glasses in a plurality of stages in a predetermined arrangement direction, a light source that emits inspection light toward the cassette, a scanning unit that performs scanning with the inspection light in the arrangement direction, a light reflection unit that is disposed on the back surface side of the cassette and reflects the inspection light emitted from the light source, a light detection unit that detects reflected light including the inspection light reflected by at least one of the light reflection unit, the cassette, and the slide glass, and outputs a detection signal, and an information generation unit that generates holding information on a holding position and/or a holding state of the slide glass held in the cassette on the basis of the detection signal.

A microscope includes a holder for holding a sample, an objective for imaging at least apart of a sample held by the holder, a detection module, a control unit for setting the focus position of the objective in a first direction for the recording by means of the detection module, and a focusing module for maintaining a set focus position of the objective. The focusing module includes the control unit, a second detector and first focusing optics with adjustable focal length. The focusing module is switchable into a focus-hold mode, wherein an intensity-modulated object is imaged into the sample via the first focusing optics and the objective, and an image of the imaged object is recorded by means of the second detector. The control unit holds the focus position of the objective on the set focus position, based upon the recording of the second detector.

A microscope includes a holder for holding a sample, an objective for imaging at least apart of a sample held by the holder, a detection module, a control unit for setting the focus position of the objective in a first direction for the recording by means of the detection module, and a focusing module for maintaining a set focus position of the objective. The focusing module includes the control unit, a second detector and first focusing optics with adjustable focal length. The focusing module is switchable into a focus-hold mode, wherein an intensity-modulated object is imaged into the sample via the first focusing optics and the objective, and an image of the imaged object is recorded by means of the second detector. The control unit holds the focus position of the objective on the set focus position, based upon the recording of the second detector.

This disclosure is directed to system for transferring a substrate, such as a microscope slide, and holding the substrate within at least one device. The system includes a holder for holding the substrate and a gripper for transferring the substrate, such as between a cassette or stack and the holder. A method is also discussed herein.

This disclosure is directed to system for transferring a substrate, such as a microscope slide, and holding the substrate within at least one device. The system includes a holder for holding the substrate and a gripper for transferring the substrate, such as between a cassette or stack and the holder. A method is also discussed herein.