A gaze tracking system includes a contact lens, a photodetector element, a light conditioning element and electronics. The contact lens includes a fiducial having a position. The photodetector element receives a light signal from the fiducial and provides a photodetector output signal. The light signal provides a light intensity pattern at the photodetector. The optical conditioning element receives the light signal and provides a variation in the light intensity pattern on the photodetector in response to changes in the position of the fiducial. And the electronics process the photodetector output signal to calculate the position of the fiducial. A method includes detecting a light signal from a fiducial included in a contact lens, and tracking the contact lens by analyzing the light signal.

A gaze tracking system includes a contact lens, a photodetector element, a light conditioning element and electronics. The contact lens includes a fiducial having a position. The photodetector element receives a light signal from the fiducial and provides a photodetector output signal. The light signal provides a light intensity pattern at the photodetector. The optical conditioning element receives the light signal and provides a variation in the light intensity pattern on the photodetector in response to changes in the position of the fiducial. And the electronics process the photodetector output signal to calculate the position of the fiducial. A method includes detecting a light signal from a fiducial included in a contact lens, and tracking the contact lens by analyzing the light signal.

Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for obtaining a fluorescence microscope image that depicts a sample and a plurality of fiducial markers, identifying the plurality of fiducial markers in the image, and using the plurality of fiducial markers to register the image. The sample and the plurality of fiducial markers have a common fluorescence color, and identifying the plurality of fiducial markers in the image includes comparing a spatial intensity distribution of a plurality of fluorescent regions of the image to a reference distribution function.

A sighting device, including an optical element having a concave reflection surface and an aiming light source and forming in a visual field frame, comprises a main-body housing section that houses the optical element and the aiming light source and has an opening on an upper surface side, a cover member that covers the upper surface side of the main-body housing section, and a link mechanism that couples the main-body housing section and the cover member and moves the cover member with respect to the main-body housing section. The cover member is moved by the link mechanism between a closed position where the cover member covers the opening of the main-body housing section and an open position where the cover member is disposed in a position separated from the opening of the main-body housing section and forms an optical path of the aiming light.

The invention relates to a plasmonic optical security component comprising two layers (2, 4) made of transparent dielectric material and a metal layer (3) arranged between said transparent dielectric material layers in order to form two dielectric-metal interfaces (31, 32). The metal layer is structured to form, on a first coupling region, a first periodic, two-dimensional coupling array (C.sub.1) which is capable of coupling surface plasmon modes, which are supported by said dielectric-metal interfaces, to an incident light ray, the first coupling array having a profile which does not have point symmetry in any of the directions thereof, and, on a second coupling region, a second periodic, two-dimensional coupling array (C.sub.2) which is capable of coupling surface plasmon modes, which are supported by said dielectric-metal interfaces, to an incident light ray, the second coupling array having a profile which does not have point symmetry in any of the directions thereof and is different from that of the first coupling array.

A method of image-based analysis of multiple samples includes using a sample holder having multiple locations of interest and multiple focal structures that are each associated, one or more, with the multiple locations of interest, wherein the multiple samples are dispersed across the multiple locations of interest and obtaining image areas of the multiple locations of interest. Multiple digital image areas are thus obtained for use in an analysis of the multiple samples with each of the image areas including at least one of the locations of interest and at least one of the focal structures. An image processing algorithm is used to analyse each of the digital image areas and check if the focal structure indicates that the image area is in clear focus. An indication is provided and/or remedial action is taken if the image processing algorithm indicates that any digital image areas are out of focus.

Provided is an image forming method including a step of imagewisely applying, onto a base material by an inkjet method, at least two inks containing a polymerizable liquid crystal compound, a chiral compound, and a polymerization initiator and having reflection wavelengths different from each other, such that the total application amount of the inks provides an image area ratio of 50% or more in an image forming region.

This disclosure is directed to optical microscope calibration devices that can be used with optical microscopes to adjust the microscope imaging parameters so that images of samples can be obtained below the diffraction limit. The microscope calibration devices include at least one calibration target. Each calibration target includes a number of features with dimensions below the diffraction limit of a microscope objective. Separate color component diffraction limited images of one of the calibration targets are obtained for a particular magnification. The color component images can be combined and image processed to obtain a focused and non-distorted image of the calibration target. The parameters used to obtain the focused and non-distorted image of the calibration target can be used to obtain focused and non-distorted images of a sample for the same magnification by using the same parameters.

A microscope system includes a microscope body, an XY stage mounted on the microscope body and including a stage configured to place a slide as an observation target and move in an X-axis direction and a Y-axis direction perpendicular to each other, and an XY two-dimensional scale plate fixed to the stage. The XY two-dimensional scale plate is provided with a first mark that provides axis information in the X-axis direction throughout a movable range of the stage in the Y-axis direction and a second mark that provides axis information in the Y-axis direction throughout a movable range of the stage in the X-axis direction, which are used to recognize X- and Y-coordinates of the stage.

A slide on which an observation object by a microscope is placed, is provided. A first mark indicating a reference line along a first direction and a second mark indicating a specific position on an extension of the reference line along the first direction are separately arranged in a vacant area between a label area used to arrange a label and a cover glass area used to arrange the observation object and a cover glass. A position reference is provided by the specific position on the extension of the reference line along the first direction.