The printed article includes a medium having a specular reflective layer, a first line composed of a first color formed at the medium, a second line formed at the medium in a second color and formed parallel to the first line, and a prism layer formed onto at least the first line, wherein when the medium is divided into a first region, a second region, and a third region that are continuous in parallel, the first line is disposed in any one region of the first region, the second region, and the third region, the second line is disposed in any one region other than the region where the first line was formed, the prism layer is disposed across two contiguous regions including the region formed with the first line, and the section of the prism layer has a shape of a portion of the non-circular arc approximating the ellipse.

The present disclosure provides automated robotic microscopy systems that facilitate high throughput and high content analysis of biological samples, such as living cells and/or tissues. In certain aspects, the systems are configured to reduce user intervention relative to existing technologies, and allow for precise return to and re-imaging of the same field (e.g., the same cell) that has been previously imaged. This capability enables experiments and testing of hypotheses that deal with causality over time with greater precision and throughput than conventional microscopy methods.

The present disclosure provides automated robotic microscopy systems that facilitate high throughput and high content analysis of biological samples, such as living cells and/or tissues. In certain aspects, the systems are configured to reduce user intervention relative to existing technologies, and allow for precise return to and re-imaging of the same field (e.g., the same cell) that has been previously imaged. This capability enables experiments and testing of hypotheses that deal with causality over time with greater precision and throughput than conventional microscopy methods.

The disclosure relates to a reticle, and particularly a reticle having a marking feature that is translucent. A marking feature may be made from an etched pattern, a gradient, a coating, paint, a filament, or a combination thereof. Reticles may also include an additional feature, such as a center dot, crosshairs, range estimation feature, drop estimation feature, wind point-of-impact estimation feature, moving target point-of-impact feature, and combinations thereof. The additional feature may, but is not required to be, translucent.

The disclosure relates to a reticle, and particularly a reticle having a marking feature that is translucent. A marking feature may be made from an etched pattern, a gradient, a coating, paint, a filament, or a combination thereof. Reticles may also include an additional feature, such as a center dot, crosshairs, range estimation feature, drop estimation feature, wind point-of-impact estimation feature, moving target point-of-impact feature, and combinations thereof. The additional feature may, but is not required to be, translucent.

A license plate assembly includes a backing and a flexible license plate. The flexible license plate includes plural layers, including a licensing-information layer, in which ink is deposited in the form of alphanumeric characters on an underlying one of the plural layers, the alphanumeric characters providing license information. The flexible license plate optionally includes one or more holograms, and/or watermarks, and/or QR-codes. The flexible license plate is disposed on the backing, which extends beyond the perimeter of the flexible license plate, defining a marginal region. In some embodiments, plural indices are disposed in the marginal region to facilitate alignment of flexible license plate during installation thereof on a motor vehicle.

Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for obtaining a fluorescence microscope image that depicts a sample and a plurality of fiducial markers, identifying the plurality of fiducial markers in the image, and using the plurality of fiducial markers to register the image. The sample and the plurality of fiducial markers have a common fluorescence color, and identifying the plurality of fiducial markers in the image includes comparing a spatial intensity distribution of a plurality of fluorescent regions of the image to a reference distribution function.

The printed article includes a medium having a specular reflective layer, a first line composed of a first color formed at the medium, a second line formed at the medium in a second color and formed parallel to the first line, and a prism layer formed onto at least the first line, wherein when the medium is divided into a first region, a second region, and a third region that are continuous in parallel, the first line is disposed in any one region of the first region, the second region, and the third region, the second line is disposed in any one region other than the region where the first line was formed, the prism layer is disposed across two contiguous regions including the region formed with the first line, and the section of the prism layer has a shape of a portion of the non-circular arc approximating the ellipse.

An apparatus includes an optical source situated to produce a fiducial source beam, and an optical fiducial pattern generator situated to produce with the fiducial source beam at least one transient optical fiducial on a laser processing target that is in a field of view of a laser scanner situated to scan a laser processing beam across the laser processing target, so that a positioning of the laser processing beam on the laser processing target becomes adjustable relative to the at least one transient optical fiducial.

An apparatus includes an optical source situated to produce a fiducial source beam, and an optical fiducial pattern generator situated to produce with the fiducial source beam at least one transient optical fiducial on a laser processing target that is in a field of view of a laser scanner situated to scan a laser processing beam across the laser processing target, so that a positioning of the laser processing beam on the laser processing target becomes adjustable relative to the at least one transient optical fiducial.