This invention relates to methods and compositions for treating cognitive impairment associated with central nervous system (CNS) disorders. In particular, it relates to the use of inhibitors of synaptic vesicle glycoprotein 2A (SV2A), alone or in combination with valproate, in treating cognitive impairment associated with central nervous system (CNS) disorders in a subject in need or at risk thereof, including, without limitation, subjects having or at risk for age-related cognitive impairment.

A multi-mode document scanning system includes a scanning bed configured to transport a plurality of documents through a scanning area. A scanning camera is configured to image the documents. At least one illumination bank includes a plurality of illumination elements of at least two different light wavelengths interspersed on at least one illumination bank. An illumination source switching assembly controls at last some elements of one wavelength. A selection process selects a wavelength appropriate to a document to be scanned, and instructs a processor operatively coupled to the illumination source switching assembly to illuminate elements of that wavelength. A multi-mode scanning method of document scanning is also described.

Differing from conventional approaches for improving sexual dysfunction of an adult man being commonly achieved by letting the adult man administer a dosage of synthetic drug or a composition of Chinese herbal medicines, the present invention particularly discloses a method for treating male sexual dysfunction by using underpants comprising far-infrared fibers. Clinical data have proved that, after wearing this underpants for 3 months, both the men diagnosed with sexual dysfunction and the men not sure to suffer from sexual dysfunction have an apparent progress on improvements of their erectile ability, erectile quality, ejaculation control ability, and lower urinary tract symptoms (LUTS). Moreover, clinical data have also proved that, despite the fact that a male person wears the underpants provided by the present invention for three months, there is no adverse effect induced by the underpants for causing the physiological condition of the men be abnormal.

Differing from conventional approaches for improving sexual dysfunction of an adult man being commonly achieved by letting the adult man administer a dosage of synthetic drug or a composition of Chinese herbal medicines, the present invention particularly discloses a method for treating male sexual dysfunction by using underpants comprising far-infrared fibers. Clinical data have proved that, after wearing this underpants for 3 months, both the men diagnosed with sexual dysfunction and the men not sure to suffer from sexual dysfunction have an apparent progress on improvements of their erectile ability, erectile quality, ejaculation control ability, and lower urinary tract symptoms (LUTS). Moreover, clinical data have also proved that, despite the fact that a male person wears the underpants provided by the present invention for three months, there is no adverse effect induced by the underpants for causing the physiological condition of the men be abnormal.

Disclosed are a virtual reality (VR) sickness assessment method and an apparatus thereof considering a neural mismatch model. The virtual reality (VR) sickness assessment method according to an embodiment includes receiving virtual reality content, and quantitatively evaluating virtual reality sickness for the received virtual reality content using a neural network based on a pre-trained neural mismatch model. The evaluating of the virtual reality sickness may include predicting an expected visual signal for an input visual signal of the virtual reality content based on the neural mismatch model, extracting a neural mismatch feature between the predicted expected visual signal based on the neural mismatch model and an input visual signal for a corresponding frame of the virtual reality content corresponding to the expected visual signal, and evaluating a level of the virtual reality sickness based on the neural mismatch model and the extracted neural mismatch feature.

Disclosed are a virtual reality (VR) sickness assessment method and an apparatus thereof considering a neural mismatch model. The virtual reality (VR) sickness assessment method according to an embodiment includes receiving virtual reality content, and quantitatively evaluating virtual reality sickness for the received virtual reality content using a neural network based on a pre-trained neural mismatch model. The evaluating of the virtual reality sickness may include predicting an expected visual signal for an input visual signal of the virtual reality content based on the neural mismatch model, extracting a neural mismatch feature between the predicted expected visual signal based on the neural mismatch model and an input visual signal for a corresponding frame of the virtual reality content corresponding to the expected visual signal, and evaluating a level of the virtual reality sickness based on the neural mismatch model and the extracted neural mismatch feature.

A multi-chamber container with an educational function. The multi-chamber container is designed to provide a housing, with a sidewall extending between a bottom wall and a top wall, that can store food or beverage substances therein. The housing includes a primary chamber and at least one secondary chamber. The primary chamber is accessible via a primary opening, while each secondary chamber is individually accessible via a secondary opening. The container provides an educational function in that the primary chamber stores a desired liquid or solid material and the secondary chamber is empty. The primary and secondary openings are Indistinguishable to the consumer until opened from a closed state. The selection of the primary opening corresponds to a correct answer to a question displayed on, or associated with, the container.

A multi-chamber container with an educational function. The multi-chamber container is designed to provide a housing, with a sidewall extending between a bottom wall and a top wall, that can store food or beverage substances therein. The housing includes a primary chamber and at least one secondary chamber. The primary chamber is accessible via a primary opening, while each secondary chamber is individually accessible via a secondary opening. The container provides an educational function in that the primary chamber stores a desired liquid or solid material and the secondary chamber is empty. The primary and secondary openings are Indistinguishable to the consumer until opened from a closed state. The selection of the primary opening corresponds to a correct answer to a question displayed on, or associated with, the container.

Personal care devices (or apparatuses) are described to deliver/activate a bioactive compound/botanical compound/biologically active molecule (including a regulatory protein/growth factor) or a mixture of bioactive compounds/botanical compounds/biologically active molecules (including regulatory proteins/growth factors) for growth and protection of hair or rejuvenation and protection of skin, which utilizes nanoencapsulation/nanoemulsion and/or activation/photoactivation. Such devices (or apparatuses) utilize a light low intensity module/x-ray and nanooptical elements/three-dimensionally (3-D) printed micro/nanostructures. Furthermore, the personal care devices (or apparatuses) can be enhanced with an artificial intelligence (AI) algorithm and/or augmented reality (AR) application (app).

Personal care devices (or apparatuses) are described to deliver/activate a bioactive compound/botanical compound/biologically active molecule (including a regulatory protein/growth factor) or a mixture of bioactive compounds/botanical compounds/biologically active molecules (including regulatory proteins/growth factors) for growth and protection of hair or rejuvenation and protection of skin, which utilizes nanoencapsulation/nanoemulsion and/or activation/photoactivation. Such devices (or apparatuses) utilize a light low intensity module/x-ray and nanooptical elements/three-dimensionally (3-D) printed micro/nanostructures. Furthermore, the personal care devices (or apparatuses) can be enhanced with an artificial intelligence (AI) algorithm and/or augmented reality (AR) application (app).