A decontamination assembly (1) for pharmaceutical applications, comprising an isolator (2) having a manipulator chamber (3) and a plenum chamber (4) which is disposed above the manipulator chamber (3) and which can be supplied with an air flow (9) via at least one circulation fan (7) disposed in a circulating-air generation chamber, a membrane (5) for generating a laminar air flow (11) in the manipulator chamber (3) during a working operating state being disposed between the plenum chamber (4) and the manipulator chamber (3), the manipulator chamber (3) being connected to the circulating-air generation chamber (6) in an air-conducting manner via a return-air channel (12), further comprising ultrafine distributing means (19), for producing a decontaminant/air mixture based on a liquid decontaminant stock, a stock of H.sub.2O.sub.2, the ultrafine distributing means (19) being connected to the plenum chamber (4) via at least one plenum supply line (25) leading into the plenum chamber (4) so as to directly supply the plenum chamber (4) with the decontaminant/air mixture when in a decontamination operating state, wherein the ultrafine distributing means (19) are connected directly to the manipulator chamber (3) via at least one manipulator supply line (27) so as to directly supply the manipulator chamber (3) with the decontaminant/air mixture when in the decontamination operating state.

A decontamination assembly (1) for pharmaceutical applications, comprising an isolator (2) having a manipulator chamber (3) and a plenum chamber (4) which is disposed above the manipulator chamber (3) and which can be supplied with an air flow (9) via at least one circulation fan (7) disposed in a circulating-air generation chamber, a membrane (5) for generating a laminar air flow (11) in the manipulator chamber (3) during a working operating state being disposed between the plenum chamber (4) and the manipulator chamber (3), the manipulator chamber (3) being connected to the circulating-air generation chamber (6) in an air-conducting manner via a return-air channel (12), further comprising ultrafine distributing means (19), for producing a decontaminant/air mixture based on a liquid decontaminant stock, a stock of H.sub.2O.sub.2, the ultrafine distributing means (19) being connected to the plenum chamber (4) via at least one plenum supply line (25) leading into the plenum chamber (4) so as to directly supply the plenum chamber (4) with the decontaminant/air mixture when in a decontamination operating state, wherein the ultrafine distributing means (19) are connected directly to the manipulator chamber (3) via at least one manipulator supply line (27) so as to directly supply the manipulator chamber (3) with the decontaminant/air mixture when in the decontamination operating state.

Certain exemplary embodiments can provide a system comprising a substantially transparent radiation shield, which comprises transparent ammonium metatungstate. The transparent ammonium metatungstate can have a density of greater than 1.5 gram/(cubic centimeter). The substantially transparent radiation shield can be installed on tanks and/or pressure vessels, used as a transparent radiation shield in medical shielding/devices, used as windows in glove boxes, and any application where effective radiation shielding is needed with transparency. The substantially transparent radiation shield can be used in one or more articles worn by a human.

A port structure of a containment apparatus is capable of providing a highly reliable port by means of a structure with which a port can be formed in any size at any position and high airtightness thereof can be maintained. The port structure has: a port formation hole that is formed in a transparent synthetic resin sheet defining at least a part of a chamber; an inner ring member disposed on the inner surface side of the port formation hole; an outer ring member disposed on the outer surface side of the port formation hole; and a fastening member that joins the inner ring member and the outer ring member to each other while having a rim portion of the port formation hole held therebetween.

Provided are systems for filling containers with radioactive and/or other types of potentially hazardous materials. In some aspects, the systems include a shielding material that substantially defines a chamber and, preferably, substantially blocks radioactivity, a conduit extending from outside to into the chamber, and a unit that is disposed in the chamber proximal to the conduit and is adapted to receive a capsule through the conduit. The systems of the present disclosure can further comprise a syringe, a syringe controller that is disposed in the dispensing chamber and adapted to meter an aliquot from a radioactive stock solution and inject the aliquot into the capsule or a vial.

A glove box has an enclosure having a glass window top and gloves mounted to the front wall. The enclosure can be tilted to so that one or other, or both, of the work piece and the window can be placed at an angle such as may facilitate processing. The glove box has an environmental control system to both to permit flushing with inert or other desired gases, and to permit heating or cooling. The workstand may have cooling passages as well. Controls are mounted inside the enclosure chamber to permit the operator to change working parameters without removing his or her hands from the gloves. A parameter status display may be located outside the enclosure. The window may be provided with a movable smoked glass filter for use during welding. The workstand may be independently adjustable for angle within the enclosure. The glove box has electrical and cooling service penetrations to permit use of a welding electrode.

The invention relates to a portable containment device for manipulating organic and/or chemical substances, which includes:

a transporting case including two half-cases (2, 3) connected by a hinged structure (4) such as to be movable between a closed position (F), in which the half-cases (2, 3) are against one another and define a stowing space for at least the hinged structure (4), and an open position (0), in which the half-cases (2, 3) are spaced apart from one another by being maintained vertical by the hinged structure (4) and in which the half-cases (2, 3) and the hinged structure (4) form a supporting structure for a flexible containment enclosure (20);

and a plastic, removable and flexible containment enclosure (20) that is at least partially transparent, for forming a generally parallelepiped foldable isolation chamber provided with means (31, 32) for accessing the inside of the enclosure and with means (21) for attachment to the supporting structure. The containment enclosure (20) is collapsible inside the transporting case in the closed position (F). The invention also relates to a removable, flexible enclosure for such a device.

Certain exemplary embodiments can provide a system comprising a substantially transparent radiation shield, which comprises transparent ammonium metatungstate. The transparent ammonium metatungstate can have a density of greater than 1.5 gram/(cubic centimeter). The substantially transparent radiation shield can be installed on tanks and/or pressure vessels, used as a transparent radiation shield in medical shielding/devices, used as windows in glove boxes, and any application where effective radiation shielding is needed with transparency. The substantially transparent radiation shield can be used in one or more articles worn by a human.

The invention relates to a bidirectional device for changing a handling glove from the inside towards the outside and from the outside towards the inside of a glove box under containment. The device is intended for replacing a used glove (60) with a new glove. The device comprises a cuff (6) sealingly connected to a cuff sleeve (20) and a glove (60) made of a flexible material sealingly connected to a glove sleeve (40). The glove sleeve comprises snap-fitting studs on the outside and the cuff sleeve comprises axial ramps (30). The snap-fitting studs of the glove sleeve slide in the axial ramps of the cuff sleeve until the glove sleeve is locked, forming, once assembled, a sealed assembly referred to as cuff port (10).

A device for purifying and formulating a radiopharmaceutical compound includes an automated purification subsystem that automates the loading of a sample into a sample loop for downstream purification via HPLC. A column selector valve is provided to select from one of a plurality of columns. Fractions can be collected as well as the desired product. The device includes an automated formulation subsystem that first sends the product to a dilution reservoir prior to being pneumatically pushed onto a solid phase extraction (SPE) cartridge. Automated rinse, elution, and reconstitution are also performed with the automated formulation subsystem. The device may be directly coupled to the output of an automated radiosynthesizer.