G01F1/661

Automated Cell Sorting Stage and Methods For Using Same
20230111548 · 2023-04-13 ·

Aspects of the disclosure include systems for sorting particles of a sample in a flow stream (e.g., a biological sample containing cells). Systems according to certain embodiments include a flow cell configured to propagate a sample through a flow stream, a light source configured to irradiate particles of the sample in the flow stream, a photodetector configured to detect light from the irradiated particles and a support stage operationally coupled to the photodetector, where the support stage includes a closed-loop feedback position encoder that is configured to adjust position in the X-Y plane in response to a data signal generated by the photodetector in response to light from the irradiated particles. Methods for sorting particles using the subject systems are also described. Non-transitory computer readable storage medium are also provided.

Automated Cell Sorting Stage and Methods For Using Same
20230111548 · 2023-04-13 ·

Aspects of the disclosure include systems for sorting particles of a sample in a flow stream (e.g., a biological sample containing cells). Systems according to certain embodiments include a flow cell configured to propagate a sample through a flow stream, a light source configured to irradiate particles of the sample in the flow stream, a photodetector configured to detect light from the irradiated particles and a support stage operationally coupled to the photodetector, where the support stage includes a closed-loop feedback position encoder that is configured to adjust position in the X-Y plane in response to a data signal generated by the photodetector in response to light from the irradiated particles. Methods for sorting particles using the subject systems are also described. Non-transitory computer readable storage medium are also provided.

Flow rate measurement and control of infusion devices

An infusion apparatus includes a housing and a chamber configured to be connected to the housing. The apparatus further includes a weight sensor coupled to a load connector connected to the housing and an optical sensor disposed in the housing. The weight sensor is configured to generate a first signal based on a measured weight of the fluid container attached to the housing in a weight-bearing configuration. The optical sensor is configured to generate a second signal based on detecting drops of the fluid traversing the chamber. The apparatus also includes a flow control mechanism to control a flow rate of the fluid into an outlet channel. The apparatus includes one or more processing devices configured to perform operations including transmitting a control signal to the flow control mechanism to adjust the flow rate.

Flow rate measurement and control of infusion devices

An infusion apparatus includes a housing and a chamber configured to be connected to the housing. The apparatus further includes a weight sensor coupled to a load connector connected to the housing and an optical sensor disposed in the housing. The weight sensor is configured to generate a first signal based on a measured weight of the fluid container attached to the housing in a weight-bearing configuration. The optical sensor is configured to generate a second signal based on detecting drops of the fluid traversing the chamber. The apparatus also includes a flow control mechanism to control a flow rate of the fluid into an outlet channel. The apparatus includes one or more processing devices configured to perform operations including transmitting a control signal to the flow control mechanism to adjust the flow rate.

Monitoring device including an emitter emitting electromagnetic radiation and a detector positioned to receive the radiation to determine one or more rolling average flow rates

A monitoring device provided for monitoring the delivery of fluids through a drip chamber. The device includes an electromagnetic radiation (EMR) source and an EMR detector. The device includes a tubing set mount for receiving a flange or other portion of a tubing set, such that fluid falling through the drip chamber of the tubing set is detected by the detector. The device is operable to determine one or more rolling averages based on intervals of drops or time.

FLOW INSTRUMENT

A fluid handling system for supplying a working fluid to a fluid flow instrument is disclosed. The system includes a controller configured to receive sensor signals indicative of a deformation of a flexible barrier located between a control fluid volume containing a control fluid and a working fluid volume containing the working fluid. Based on the sensor signals, the controller may send signals to control the operation of a working fluid flow generator in order to regulate or control the fluid characteristic of the working fluid being provided to the fluid flow instrument.

OBJECT SEPARATING

An object separator may include a substrate, a fluid channel supported by the substrate, a pair of electrodes along the fluid channel to form a dielectrophoretic force to interact with an object entrained in a fluid, and an inertial pump supported by the substrate and positioned within the fluid channel to move the fluid along the fluid channel.

Optical fiber flow velocity measuring apparatus and method integrating high and low ranges

Disclosed is an optical fiber flow velocity measuring apparatus and method integrating high and low ranges. The apparatus includes an integrated optical fiber flow velocity sensor, the integrated optical fiber flow velocity sensor includes a sensor body; a fluid channel, a fluid through hole, a full-pressure channel, a static-pressure channel, a low-pressure chamber and a high-pressure chamber are provided inside the sensor body; a first optical fiber sensing element is provided between the low-pressure chamber and the high-pressure chamber; a second optical fiber sensing element is provided in the fluid through hole and is perpendicular to a flow direction of a fluid to be measured; the first optical fiber sensing element and the second optical fiber sensing element are sequentially connected in series through a single-mode optical fiber; both ends of the single-mode optical fiber are connected into a wavelength division multiplexer; a pump light source is connected with the wavelength division multiplexer through a common optical fiber; an optical fiber grating demodulator is connected with the wavelength division multiplexer through a common optical fiber; and a flow velocity arithmetic unit is electrically connected with a optical fiber grating demodulator. It's an object of the present disclosure to solve the problems that the electric circuit is too complicated and that it is not easy to integrate in one apparatus when flow velocity conversion devices based on different principles are integrated.

Production logging inversion based on DAS/DTS
11649700 · 2023-05-16 · ·

A method of optimizing production of a hydrocarbon-containing reservoir by measuring low-frequency Distributed Acoustic Sensing (LFDAS) data in the well during a time period of constant flow and during a time period of no flow and during a time period of perturbation of flow and simultaneously measuring Distributed Temperature Sensing (DTS) data from the well during a time period of constant flow and during a time period of no flow and during a time period of perturbation of flow. An initial model of reservoir flow is provided using the LFDAS and DTS data; the LFDAS and DTS data inverted using Markov chain Monte Carlo method to provide an optimized reservoir model, and that optimized profile utilized to manage hydrocarbon production from the well and other asset wells.

Production logging inversion based on DAS/DTS
11649700 · 2023-05-16 · ·

A method of optimizing production of a hydrocarbon-containing reservoir by measuring low-frequency Distributed Acoustic Sensing (LFDAS) data in the well during a time period of constant flow and during a time period of no flow and during a time period of perturbation of flow and simultaneously measuring Distributed Temperature Sensing (DTS) data from the well during a time period of constant flow and during a time period of no flow and during a time period of perturbation of flow. An initial model of reservoir flow is provided using the LFDAS and DTS data; the LFDAS and DTS data inverted using Markov chain Monte Carlo method to provide an optimized reservoir model, and that optimized profile utilized to manage hydrocarbon production from the well and other asset wells.