G01N1/38

MICROFLUIDIC SYSTEMS AND METHODS FOR REDUCING THE EXCHANGE OF MOLECULES BETWEEN DROPLETS

The present invention generally relates to systems and methods to create stable emulsions with low rates of exchange of molecules between microdroplets.

MICROFLUIDIC SYSTEMS AND METHODS FOR REDUCING THE EXCHANGE OF MOLECULES BETWEEN DROPLETS

The present invention generally relates to systems and methods to create stable emulsions with low rates of exchange of molecules between microdroplets.

METHOD FOR ADAPTING THE CONCENTRATION OF A SAMPLE GAS IN A GAS MIXTURE TO BE ANALYSED BY A GAS CHROMATOGRAPH ASSEMBLY, AND CHROMATOGRAPH ASSEMBLY THEREFORE
20230021741 · 2023-01-26 ·

Method for adapting the concentration of a sample gas in a gas mixture to be analysed by a gas chromatograph assembly (10), the gas chromatograph assembly (10) comprising a sample gas inlet (20) for introducing a sample gas to be analysed, a secondary gas inlet (40), a gas chromatograph infrared sensor (12), a gas chromatograph column (26), and a gas chromatograph bypass (28) parallel to the column (26), characterized by a) introducing an amount of sample gas through the sample gas inlet (20), b) introducing an amount of secondary gas through the secondary gas inlet (40), c) mixing the sample gas and the secondary gas to a gas mixture and conducting the gas mixture via the gas chromatograph bypass (28), d) circulating the gas mixture in a gas conducting loop (52) comprising the gas chromatograph bypass (28), the gas chromatograph infrared sensor (12) and not comprising the gas chromatograph column (26), e) analysing the gas mixture thus obtained by means of gas chromatography employing the gas chromatograph column (26) and the gas chromatograph infrared sensor (12).

METHOD FOR ADAPTING THE CONCENTRATION OF A SAMPLE GAS IN A GAS MIXTURE TO BE ANALYSED BY A GAS CHROMATOGRAPH ASSEMBLY, AND CHROMATOGRAPH ASSEMBLY THEREFORE
20230021741 · 2023-01-26 ·

Method for adapting the concentration of a sample gas in a gas mixture to be analysed by a gas chromatograph assembly (10), the gas chromatograph assembly (10) comprising a sample gas inlet (20) for introducing a sample gas to be analysed, a secondary gas inlet (40), a gas chromatograph infrared sensor (12), a gas chromatograph column (26), and a gas chromatograph bypass (28) parallel to the column (26), characterized by a) introducing an amount of sample gas through the sample gas inlet (20), b) introducing an amount of secondary gas through the secondary gas inlet (40), c) mixing the sample gas and the secondary gas to a gas mixture and conducting the gas mixture via the gas chromatograph bypass (28), d) circulating the gas mixture in a gas conducting loop (52) comprising the gas chromatograph bypass (28), the gas chromatograph infrared sensor (12) and not comprising the gas chromatograph column (26), e) analysing the gas mixture thus obtained by means of gas chromatography employing the gas chromatograph column (26) and the gas chromatograph infrared sensor (12).

Pre-Processing Method
20230028235 · 2023-01-26 ·

In a pretreatment method, in first step, a sample is dissolved in 1,1,1,3,3,3-hexafluoro-2-propanol to prepare a first solution. In second step, an organic base is added to the first solution to prepare a second solution. In third step, the second solution is heated to obtain a substance in which an anhydrous oxide structure in the sample has been decomposed. In a fourth step, an organic solvent that has a higher boiling point than that of 1,1,1,3,3,3-hexafluoro-2-propanol and is compatible (miscible) with 1,1,1,3,3,3-hexafluoro-2-propanol is added to the second solution to prepare a third solution.

Functionalized Blood Sampling Device and Method for PEth Measurement
20230228656 · 2023-07-20 ·

A device configured for collection and subsequent testing of a blood sample of less than 10 ml, characterized in that the container includes at least one inhibitor of the enzyme phospholipase D selected from at least one of a salt of vanadium and a salt of tungsten. A method of preparing a sample for analysis of phosphatidylethanol (PEth) comprises providing a blood sample for a patient with a volume of less than 10 ml; contacting the blood sample at least one inhibitor of the enzyme phospholipase D selected from at least one of a salt of vanadium and a salt of tungsten; and admitting inhibition of phospholipase D so formation of PEth is blocked. A method of applying a coating of at least one inhibitor of the enzyme phospholipase D to a test tube and the test tube obtained by this method, wherein the method comprises stabilizing the test in a substantially vertical position; inserting a spray nozzle inside the test tube, the spray nozzle being in fluid connection to a container holding a solution comprising at least one inhibitor of the enzyme phospholipase D; spraying the solution comprising at least one inhibitor of the enzyme phospholipase D inside the test tube; and allowing the solution comprising at least one inhibitor of the enzyme phospholipase D to dry.

Functionalized Blood Sampling Device and Method for PEth Measurement
20230228656 · 2023-07-20 ·

A device configured for collection and subsequent testing of a blood sample of less than 10 ml, characterized in that the container includes at least one inhibitor of the enzyme phospholipase D selected from at least one of a salt of vanadium and a salt of tungsten. A method of preparing a sample for analysis of phosphatidylethanol (PEth) comprises providing a blood sample for a patient with a volume of less than 10 ml; contacting the blood sample at least one inhibitor of the enzyme phospholipase D selected from at least one of a salt of vanadium and a salt of tungsten; and admitting inhibition of phospholipase D so formation of PEth is blocked. A method of applying a coating of at least one inhibitor of the enzyme phospholipase D to a test tube and the test tube obtained by this method, wherein the method comprises stabilizing the test in a substantially vertical position; inserting a spray nozzle inside the test tube, the spray nozzle being in fluid connection to a container holding a solution comprising at least one inhibitor of the enzyme phospholipase D; spraying the solution comprising at least one inhibitor of the enzyme phospholipase D inside the test tube; and allowing the solution comprising at least one inhibitor of the enzyme phospholipase D to dry.

APPARATUS AND METHOD FOR MEASUREMENT OF HALOGENS IN SAMPLES
20230228722 · 2023-07-20 · ·

Apparatus and methods for determining a concentration of one or more halogen-containing ions in a sample, including but not limited to: soils, aquifers, groundwater, drinking water, soil, tissue, blood, sewage sludge, compost, and landfill leachate, Particularly, the apparatus and processes are used for the destruction of per- and polyfluoroalkyl substances (PFAS), per- and polyfluorocarbons (PFCs), pesticides, munitions, 1,4-dioxane, pharmaceuticals, microplastics, and others. High destruction efficiencies of these substances is desirable for determination of compliance with government regulations. Apparatus include batch- and continuous-type reactor systems. Processes include supercritical water oxidation (SCWO) and hydrothermal alkaline treatments (HALT).

Enhanced cell/bead encapsulation methods and apparatuses

A method of encapsulating a solid sample in a droplet, the method including flowing a continuous phase through a first fluid channel at a first flow rate; flowing a dispersed phase through a second fluid channel at a second flow rate, the dispersed phase including a plurality of particles, cells or beads; trapping the plurality of particles, cells or beads in a mixing region that receives the dispersed phase and the continuous phase; and reducing the first flow rate to encapsulate the trapped particles, cells or beads in droplets of the dispersed phase generated when the dispersed phase and the continuous phase exit the mixing region through an orifice.

Enhanced cell/bead encapsulation methods and apparatuses

A method of encapsulating a solid sample in a droplet, the method including flowing a continuous phase through a first fluid channel at a first flow rate; flowing a dispersed phase through a second fluid channel at a second flow rate, the dispersed phase including a plurality of particles, cells or beads; trapping the plurality of particles, cells or beads in a mixing region that receives the dispersed phase and the continuous phase; and reducing the first flow rate to encapsulate the trapped particles, cells or beads in droplets of the dispersed phase generated when the dispersed phase and the continuous phase exit the mixing region through an orifice.