G01N1/44

DEPARAFFINIZATION OF TISSUE UTILIZING ELECTRIC FIELD
20230053368 · 2023-02-23 ·

Paraffin-embedded tissue is prepared removing paraffin from the tissue. The paraffin is removed by generating an electric field effective to produce plasma and direct charged species of the plasma to the paraffin, thereby rendering the paraffin responsive to the electric field. The electric field may move the paraffin out from the tissue due to electrostatic force. Movement of the paraffin may be assisted by moving an electrode utilized to generate the electric field relative to the paraffin. Movement of the paraffin also may be assisted by applying a solvent and/or heat energy to the tissue.

EQUIPMENT FOR THE CONTROL OF THE INDUSTRIAL CONTAMINATION OF INDUSTRIAL COMPONENTS
20220365105 · 2022-11-17 · ·

Equipment for the control of the industrial contamination of industrial components comprising at least one base frame; and an extraction unit/device/component of contaminating impurities from at least one industrial component, mounted on the base frame and provided with a washing unit/device/component of the industrial component by way of an operating fluid adapted to remove the contaminating impurities from said industrial component, the operating fluid mixing with the contaminating impurities to obtain an operating mixture following the washing of the industrial component; and a preparation unit/device/component of at least one analysis sample of the contaminating impurities removed from the industrial component starting from the operating mixture, wherein the equipment comprises an analysis unit/device/component of the analysis sample mounted on the base frame and adapted to detect at least one analytical data which is characteristic of the contaminating impurities.

Low-Energy Consumption Solvent Dilution Device For Pre-Treating Sample

The invention discloses a low-energy consumption solvent dilution device for pre-treating samples comprising an accommodating unit, the accommodating unit including a case and an accommodating portion arranged inside the case; an input unit, which including an inlet, a second outlet and a third outlet extending into the case; a cleaning unit, which including a receiving assembly arranged below the second outlet and the third outlet, and a conveying assembly communicated with a receiving assembly. The input unit including a first tube connecting with the inlet, and a second tube and a third tube extending out of the second outlet and the third outlet, respectively.

The present invention completes dispensing and diluting the sample fixative in the box, the dispersion of the fixative is reduced. Avoid unnecessary contact for operators. It improves the safety and accuracy of the experiment, and significantly reduces energy consumption and labor costs.

In situ heat induced antigen recovery and staining apparatus and method
11585737 · 2023-02-21 ·

Contemplated herein is an automated microscope slide antigen recovery and staining apparatus and method that features a plurality of individually operable miniaturized pressurizable reaction compartments for individually and independently processing a plurality of individual microscope slides. The apparatus preferably features independently movable slide support elements each having an individually heatable heating plate. Each slide support element may support a microscope slide. Each microscope slide can be enclosed within an individual pressurizable reaction compartment. Pressures exceeding 1 atm or below 1 atm can be created and maintained in the reaction compartment prior to, during or after heating of the slide begins. Because of the ability to pressurize and regulate pressure within the reaction compartment, and to individually heat each slide, each slide and a liquid solution or reagent thereon can be heated to temperatures that could not be obtained without the enclosed pressurized environment of the reaction compartment. A reagent dispensing strip having a plurality of reconfigurable reagent modules may also be used.

In situ heat induced antigen recovery and staining apparatus and method
11585737 · 2023-02-21 ·

Contemplated herein is an automated microscope slide antigen recovery and staining apparatus and method that features a plurality of individually operable miniaturized pressurizable reaction compartments for individually and independently processing a plurality of individual microscope slides. The apparatus preferably features independently movable slide support elements each having an individually heatable heating plate. Each slide support element may support a microscope slide. Each microscope slide can be enclosed within an individual pressurizable reaction compartment. Pressures exceeding 1 atm or below 1 atm can be created and maintained in the reaction compartment prior to, during or after heating of the slide begins. Because of the ability to pressurize and regulate pressure within the reaction compartment, and to individually heat each slide, each slide and a liquid solution or reagent thereon can be heated to temperatures that could not be obtained without the enclosed pressurized environment of the reaction compartment. A reagent dispensing strip having a plurality of reconfigurable reagent modules may also be used.

Detector with detector inlet for sampling gaseous fluid

A detector inlet for providing a sample to an analytical apparatus for detecting an aerosol, the detector inlet comprising; an intake for inhaling a flow of gaseous fluid to be sampled by the analytical apparatus; a mixing region; a first conduit for carrying a first part of the flow of gaseous fluid from the intake to the mixing region; a second conduit for carrying a second part of the flow of gaseous fluid from the intake to the mixing region; and a heater configured to heat the first part more than the second part, and wherein the detector inlet is configured to combine the first part with the second part in the mixing region.

Detector with detector inlet for sampling gaseous fluid

A detector inlet for providing a sample to an analytical apparatus for detecting an aerosol, the detector inlet comprising; an intake for inhaling a flow of gaseous fluid to be sampled by the analytical apparatus; a mixing region; a first conduit for carrying a first part of the flow of gaseous fluid from the intake to the mixing region; a second conduit for carrying a second part of the flow of gaseous fluid from the intake to the mixing region; and a heater configured to heat the first part more than the second part, and wherein the detector inlet is configured to combine the first part with the second part in the mixing region.

Methods for sample preparation and testing

A method and system for analyzing a sample potentially comprising a target, comprising: (i) activating one or more components of the sample analysis system in preparation for a sample, wherein the sample analysis system comprises a heating element, a centrifuge, a thermocycler, an imager, a user interface, and a processor; (ii) obtaining a sample potentially comprising a target; (iii) adding the obtained sample to a sample preparation receptacle, the sample preparation receptacle comprising one or more reagents configured to maximize success of the sample analysis; (iv) heating the sample preparation receptacle, with the added sample, in the heating element of the sample analysis system at a first temperature for a first heating period of time; (v) centrifuging the sample preparation receptacle, after heating, for a first period of time using the centrifuge of the sample analysis system; (vi) transferring at least a portion of the sample, after centrifugation, from the sample preparation receptacle to a sample analysis receptacle, the sample analysis receptacle comprising one or more reagents configured for a qPCR reaction specific to a selected target; (vii) obtaining, via the thermocycler and imager of the sample analysis system, a fluorescence curve during a qPCR reaction; (viii) analyzing, by the process of the sample analysis system, the obtained fluorescence curve to determine a presence or absence of the selected target in the sample; and (ix) reporting, to a user by the user interface of the sample analysis system, the presence or absence of the selected target in the sample; wherein one or more steps of the method are guided by interactive instructions provided by the sample analysis system.

Methods for sample preparation and testing

A method and system for analyzing a sample potentially comprising a target, comprising: (i) activating one or more components of the sample analysis system in preparation for a sample, wherein the sample analysis system comprises a heating element, a centrifuge, a thermocycler, an imager, a user interface, and a processor; (ii) obtaining a sample potentially comprising a target; (iii) adding the obtained sample to a sample preparation receptacle, the sample preparation receptacle comprising one or more reagents configured to maximize success of the sample analysis; (iv) heating the sample preparation receptacle, with the added sample, in the heating element of the sample analysis system at a first temperature for a first heating period of time; (v) centrifuging the sample preparation receptacle, after heating, for a first period of time using the centrifuge of the sample analysis system; (vi) transferring at least a portion of the sample, after centrifugation, from the sample preparation receptacle to a sample analysis receptacle, the sample analysis receptacle comprising one or more reagents configured for a qPCR reaction specific to a selected target; (vii) obtaining, via the thermocycler and imager of the sample analysis system, a fluorescence curve during a qPCR reaction; (viii) analyzing, by the process of the sample analysis system, the obtained fluorescence curve to determine a presence or absence of the selected target in the sample; and (ix) reporting, to a user by the user interface of the sample analysis system, the presence or absence of the selected target in the sample; wherein one or more steps of the method are guided by interactive instructions provided by the sample analysis system.

Synthetic source rock with tea

A synthetic source rock including roasted tea powder and inorganic material. A technique for preparing the synthetic source rock, including grinding tea leaves to give tea powder, roasting the tea powder at a roasting temperature to give a roasted tea powder, and determining composition and porosity of the roasted tea powder.