A nebulizer system capable of identifying when activation has occurred and aerosol is being produced. The nebulizer system monitors the inhalation and exhalation flow generated by the patient and communicates proper breathing technique for optimal drug delivery. The nebulizer system may monitor air supply to the nebulizer to ensure it is within the working range and is producing, or is capable of producing, acceptable particle size and drug output rate. When a patient, caregiver or other user deposits or inserts medication into the nebulizer, the nebulizer system is able to identify the medication and determine the appropriate delivery methods required to properly administer the medication as well as output this information into a treatment log to ensure the patient is taking the proper medications. The system is able to measure the concentration of the medication and volume of the medication placed within the medication receptacle, e.g., bowl.

A method and system for imaging thermodynamic phase of clouds includes obtaining a spatially-resolved polarimetric image of a region of the sky containing a cloud using a multipixel image sensor having multiple channels corresponding to different wavelength bands, determining a value of the Stokes S.sub.1 polarization parameter of incident light on each pixel corresponding to a portion of the image containing the cloud for multiple channels corresponding to different wavelength bands, and determining the thermodynamic phase of the cloud within the image based on the values of the Stokes S.sub.1 polarization parameter. The Stokes S.sub.1 polarization parameter values determined for a first channel corresponding to a first wavelength band is used to determine a liquid thermodynamic phase, and the Stokes S.sub.1 polarization parameter values determined for a second channel corresponding to a second, shorter wavelength band is used to determine an ice thermodynamic phase.

An apparatus and method for testing dissolution properties of a drug, especially anti-inflammatory drugs administered by aerosol into the respiratory system. The apparatus shortens the time it takes for a drug to dissolve and thus provides for rapid testing of new drugs for quality control as well as for regulatory purposes. It is suitable for evaluating bioequivalence or to study the pharmacokinetics of drugs administered into the respiratory system. This method shortens dissolution times for testing a drug to about 10 and 20 minutes and thus provides for rapid testing.

Various embodiments are directed to a device for detecting a particle liquid content characteristic comprising: one or more fluid flow device inlets configured to receive at least one fluid sample comprising a first plurality of particles and a second plurality of particles, the device being configured to determine a particle liquid content characteristic based at least in part on a comparison of first particle data and second particle data. In various embodiments, the device may comprise a heating element configured to heat at least a portion of particles within the second fluid sample. In various embodiments, the device may comprise a fluid sensor configured to generate first particle data using an optical scattering operation and a fluid composition sensor configured to generate second particle data using a particle imaging operation. Various embodiments are directed to systems and methods for controlling a fluid flow monitoring system.

A method for monitoring the media flow of a jet of droplets is intended to enable reliable process management, especially in industrial applications, in a particularly simple and resource-saving manner. For this purpose signal signatures assigned to individual droplets are continuously recorded by time-resolved measurement of the intensity of the scattered light of a light beam crossing the droplet beam, from which a diagnostic parameter characteristic of the droplet beam is determined.

A concentration measuring device includes a circulation passage, an aspirator, a differential pressure sensor, and a control unit. The aspirator is disposed in a fuel tank and is connected to the circulation passage. While a gas flows from a gaseous layer within a fuel tank through the circulation passage due to a negative pressure generated in the aspirator, the differential pressure sensor measures a pressure difference of the gas within the circulation passage between an upstream side of a narrowed part, having a narrower passage area than an adjacent portion of the circulation passage, and a downstream side of the narrowed part. The control unit is configured to calculate a density of the fuel vapor from the pressure difference of the gas and to calculate a concentration of the fuel vapor from the density of the fuel vapor.

Embodiments of the invention are directed to an optoelectronic device for detection and identification of individual water droplets, ice crystals, dust particles and volcanic ash particles, the device comprising a source of ultraviolet collimated monochromatic radiation that illuminates an area of air external to the aircraft through which freely pass individual atmospheric particles to create an illuminated sample volume of air; an optical surveillance system for monitoring the clarity of light transmission through the light transmissive window to indicate a need for preventive maintenance; a first optical detection system that is constructed and arranged to collect light scattered from individual particles over an explicit angle ranging from 137° to 173° that defines the illuminated sample volume for measurement of S and P components of return scattered light from the sample volume to photodetectors that provide signals representative of intensity and change in polarization state caused by the interaction of particles with the incident illumination in the sample volume; a second optical detection system for selectively detecting fluorescence emanating from individual ash particles over an explicit angle ranging from 137° to 173° that defines the illuminated sample volume for measurement of fluoresence from the sample volume to a photodetector that provide a signal representative of intensity caused by the interaction of particles with the incident illumination in the sample volume; a signal processor that is constructed and arranged to condition the signals from the photodetectors by removing electronic noise, restoring baseline shifts and analyzing the pulse shapes to provide processed signals; a signal analyzer configured to operate upon the processed signals for extraction of data representing maximum amplitude, width, rise time and fall time of individual pulses in the S and P components, and the magnitude of the fluorescence signal which correlates to the size and/or composition of ash particles present; an information synthesizer that receives the data and produces analytical results allocated to particles by particle type including equivalent optical diameter (EOD), number and mass size distributions, and number and mass concentrations, the particle type being selected as at least one member among the group consisting of individual water droplets, ice crystals, dust particles and volcanic ash particles; and a report generator that creates an information packet utilizing information from the information synthesizer to assist in decision making related to hazard avoidance for aircraft flight, the optoelectronic system being adapted for mounting

A nebulizer system capable of identifying when activation has occurred and aerosol is being produced. The nebulizer system monitors the inhalation and exhalation flow generated by the patient and communicates proper breathing technique for optimal drug delivery. The nebulizer system may monitor air supply to the nebulizer to ensure it is within the working range and is producing, or is capable of producing, acceptable particle size and drug output rate. When a patient, caregiver or other user deposits or inserts medication into the nebulizer, the nebulizer system is able to identify the medication and determine the appropriate delivery methods required to properly administer the medication as well as output this information into a treatment log to ensure the patient is taking the proper medications. The system is able to measure the concentration of the medication and volume of the medication placed within the medication receptacle, e.g., bowl.

Systems and methods for improved fluid dispensing process control using a machine learning tool are disclosed. In an example method, successive portions of viscous fluid are dispensed by a dispensing device according to operating parameters to train a machine learning tool to associate defect classifications with images of dispensed portions and/or operating parameters associated with dispensing the dispensed portions. The trained machine learning tool is then used in a closed loop fashion in production to detect and correct for defects associated with the dispensed portions to improve quality and production efficiency.

An optical sensor for an aircraft includes two detectors, a light source, and a controller. The detectors are oriented along detector paths and have tilt angles and fields of view. The detectors are configured to detect light reflected from an illumination volume and to generate detector signals that correspond to intensities of detected light. The tilt angles are equal such that each detector is oriented in an opposite direction within a plane containing a light source path and the detector paths. The light source is oriented along the light source path and is configured to illuminate the illumination volume which overlaps with the fields of view within a predetermined distance range. The controller is configured to receive the detector signals, detect whether a cloud is present based upon the detector signals, determine a cloud phase, and calculate a density of the detected cloud.