A high-throughput optofluidic device for detecting fluorescent droplets is disclosed. The device uses time-domain encoded optofluidics to detect a high rate of droplets passing through parallel microfluidic channels. A light source modulated with a minimally correlating maximum length sequences is used to illuminate the droplets as they pass through the microfluidic device. By correlating the resulting signal with the expected pattern, each pattern formed by passing droplets can be resolved to identify individual droplets.

A slurry monitoring device, a CMP system and a method of in-line monitoring a slurry are provided. The slurry monitoring device incudes a slurry metrology cell, a plurality of light sources and at least one optical detector. The slurry metrology cell is configured to accommodating a slurry. The light sources are configured to emit light beams on the slurry in the slurry metrology cell. The light sources include a first light source configured to emit a first light beam having a first wavelength, and a second light source configured to emit a second light beam having a second wavelength longer than the first wavelength. The at least one optical detector is configured to detect an intensity of the light beams scattered by abrasive particles in the slurry.

A device for detecting particles in a lubricating oil of a machine, comprising a particle separator; at least one particle detector; a bypass conduit for the particle-concentrating oil, fluidly connected to an oil outlet of the particle separator, concentrating the particles; and wherein the at least one particle detector is operatively mounted on the bypass conduit so as to be able to detect particles in the bypass conduit.

A high resolution fluorescence imaging device includes a light guide plate having a fluid channel which allows a solution containing a fluorescent sample to pass; a light source disposed on a side of the light guide plate to irradiate light inward the light guide plate; an image sensor disposed under the light guide plate;

and a thin film interposed between the light guide plate and the image sensor, wherein the thin film has a first surface having a plurality of pillars and a second surface, the pillars separate the light guide plate and the image sensor apart from each other, and the second surface is bonded to the light guide plate. According to an embodiment, since the light guide plate acts in place of a filter element, it is possible to manufacture in ultrasmall size and achieve multiple fluorescence imaging without replacing a filter.

A method of analyzing and/or sorting selected cells or other biological components, for example for cell-based therapy, includes sampling a sample with an open end of a probe to obtain a fluid stream with the sample in it. The probe with the open end also has a fluid supply to convey fluid to the open end, and a fluid exhaust to convey the fluid stream away from the open end. The method then includes conveying the fluid stream to a flow cytometer and analyzing the fluid stream by flow cytometry; and/or separating it into at least two components. An apparatus with the probe connected to the flow cytometer may support this method. The method can provide for sampling of multiple samples efficiently, in particular to select cells for cell-based therapies.

This disclosure provides techniques for detecting and/or inhibiting corrosion of a distribution/recirculation network for a fluid, e.g., an aqueous matrix (liquid). For example, the disclosed techniques can be used to measure and/or predict degeneration of pipes, solder joints and various other plumbing fixtures in a water distribution network or heat transfer recirculation network caused as a function of variation in environmental parameters. In one embodiment, a system builds a database by measuring metal corrosion (e.g., from lead or copper pipe, solder joint or other type of plumbing vessel or fixture) and correlating degradation of a layer of protective scale and/or metal concentrations present with measured environmental parameters; later, as conditions vary, the database (or associated correlation weights/values) may be used to predict degradation of scale health and/or corrosion stemming from short and/or long term water conditions, and to effectuate advance mitigation.

An internal deformation analysis experimental device and method for a three-dimensional particle material, including an internal deformation analysis experimental device for a three-dimensional particle material includes: several particles, which are transparent solids; an infiltration liquid, the refractive index of the particles being the same as that of the infiltration liquid; a container, configured to accommodate the particles and the infiltration liquid; a laser device, arranged on an outer side of the container, the infiltration liquid being able to generate fluorescent light when laser emitted by the laser device irradiates the infiltration liquid; a recording apparatus, arranged on the outer side of the container and configured to collect and acquire a sequential image of the particles; and a computing terminal, the recording apparatus sending the acquired sequential image of the particles to the computing terminal, and the computing terminal constructing a three-dimensional particle system through the sequential image of the particles.

The present invention describes a fluidic device for measuring at least one of corpuscle mass density and weight. The fluidic device comprises a sedimentation chamber fluidly connected to an inlet channel configured to be immersed in a liquid. The fluidic device further comprises a pumping system connected to the sedimentation chamber. The pumping system is adapted to control the flow of liquid in the sedimentation chamber. A processor of the fluidic device is configured to obtain corpuscle data related to a corpuscle in at least one region of the sedimentation chamber; and calculate at least one of corpuscle mass density and weight based on the data received.

Magnetic chip detectors and associated for detecting metallic chips in engine fluid of an engine are provided. A magnetic chip detector includes first and second magnetic chip capture zones. The first magnetic chip capture zone includes a first electrically conductive terminal spaced apart from a second electrically conductive terminal to define a first chip-receiving gap therebetween. The second magnetic chip capture zone includes a third electrically conductive terminal and either the second electrically conductive terminal or a fourth electrically conductive terminal to define a second chip-receiving gap therebetween. The magnetic chip detector includes an electric circuit including both the first chip-receiving gap and the second chip-receiving gap. The electric circuit provides an output indicative of a chip detection by one or both of the first magnetic chip capture zone and the second magnetic capture zone.

A filter for filtering particulates from a fluid stream includes a filter element with a filter medium and a metallic debris sensor assembly. The metallic debris sensor assembly includes a core and a coil of electrically-conductive wire. The core has a first end, a second end, and an intermediate portion interposed between the first and second ends. The first end is disposed in spaced relationship with the second end such that a measurement area is disposed therebetween. The coil of electrically-conductive wire is wound around the intermediate portion of the core. The core is adapted to generate a magnetic field in the measurement area when an electrical current is passed through the coil. At least a portion of the filter medium of the filter element is disposed within the measurement area. The filter can be incorporated into a wear detection system and used in methods of monitoring.