An object of the present claimed invention is to improve cell cooling performance, keep a temperature of a dispersion medium constant, and improve measurement accuracy. The particle size distribution measuring device of this invention comprises a cell holding body 31 that holds a cell 2 housing a measurement sample and that is rotated by a motor 322, a case (C) having a housing space (S) for rotatably housing the cell holding body 31, and a cooling mechanism 8 for cooling the cell 2. The cooling mechanism 8 comprises a cooler 81, and a supply channel 82 that supplies a gas that has been cooled by the cooler 81 to the housing space (S).

A device for monitoring a bioreactor is configured for in-situ analysis, e.g., by NIR, without the need for withdrawing a sample into a sample cell or into an ex-situ arrangement. The device can be inserted into a port of the bioreactor and provides a sample detection region defined by an optical element such as a lens and a photodetector. The electrical signal obtained from a photodetector that is part of the device can be directed to an analyzer via a detachable electrical connection.

Systems, apparatuses, and methods for monitoring an environment are provided. One system includes a monitoring unit positioned within an environment and including an acoustic sensor configured to generate detected acoustic data regarding acoustics in the environment, and a controller having one or more processors and one or more non-transitory memory devices that store instructions for controlling the one or more first processors to receive and store the detected acoustic data, determine, based on the detected acoustic data, whether a noise is above a threshold, and determine, based on the detected acoustic data and that the noise is above the threshold, an estimated source of the noise.

A method for monitoring the media flow of a jet of droplets is intended to enable reliable process management, especially in industrial applications, in a particularly simple and resource-saving manner. For this purpose signal signatures assigned to individual droplets are continuously recorded by time-resolved measurement of the intensity of the scattered light of a light beam crossing the droplet beam, from which a diagnostic parameter characteristic of the droplet beam is determined.

A method can be provided for analyzing a fluidic sample with dispersed particles. Using such exemplary method, it is possible to irradiate the sample with light, so that the photons of the light transfer momentum to the particles. It is also possible to measure at least one property of the particles that is altered by the momentum transfer. The light can be a propagating beam with an intensity distribution that has gradients pointing to more than one point within each plane normal to the direction of propagation, while varying steadily along the direction of propagation, and/or a 3D vortex trap beam that is configured to confine the particles in a three-dimensional volume by means of high-intensity gradients. An exemplary device can also be provided (e.g., for performing the method), comprising a chamber for holding a sample that is elongate along an axis and configured to pass a beam of light along the axis. The chamber can have a conical inner cross section that substantially expands in the direction of propagation of the beam.

An apparatus for monitoring particles in a chemical solution includes a chemical solution supply device that stores a chemical solution and supplies the chemical solution according to a work start signal of a control unit, a first supply channel that is connected with the chemical solution supply device to supply the chemical solution, a filter that is connected with the first supply channel to purify the chemical solution, a branch channel and a main channel that are branched from the filter, a drain valve that is connected with the branch channel to open and close the branch channel, a particle monitor that is connected with the main channel to detect the amount of particles in the chemical solution, and a dispenser unit that receives the chemical solution from the particle monitor to supply the chemical solution to an object to be worked.

A method for calibrating a contaminant detection device includes fluidly connecting the contaminant detection device in series to a test reservoir and a light-obscuration-type particle counter, pumping low-end, intermediate, and high-end test dust dilutions through the contaminant detection device and the particle counter until a particle count measured by the particle counter for each of the successive test dust dilutions stabilizes, and setting a low-end gain, an intermediate gain, and a high-end gain for the contaminant detection device based on the stabilized particle counts for each of the test dust dilutions using a first-sized test dust grade. A bubble counting gain of an aeration threshold for the device may be set according to a second test dust grade greater in size than the first-sized test dust grade, and associated with a voltage signal produced by the contaminate detection device indicative of the presence of an air bubble contained within the fluid during use of the fluid in heavy machinery.

Methods, systems, and apparatus, including computer programs encoded on computer storage media, for processing recycled concrete aggregate (RCA). One of the methods includes obtaining first optical measurements of RCA particles as the RCA particles are conveyed past the first optical sensors; determining, based on the first measurements, an initial characterization of the RCA particles; iteratively performing a carbonation process on the RCA particles, obtaining second optical measurements of the RCA particles, and determining, from the second measurements, a second characterization of the RCA particles, wherein conditions of the carbonation process are initially set based on the initial characterization, and the conditions of the carbonation process are adjusted based on the second characterization; ceasing the iterative performance of the carbonation process in response to the second characterization meeting target carbonation characteristics; iteratively performing a densification process on the RCA particles, obtaining third optical measurements of the RCA particles, and determining, from the third measurements, a third characterization of the RCA particles, wherein conditions of the densification process are initially set based on the initial characterization or the second characterization, and the conditions of the densification process are adjusted based on the third characterization; and ceasing the iterative performance of the densification process in response to the third characterization meeting target densification characteristics.

A device for monitoring a bioreactor is configured for in-situ analysis, e.g., by NIR, without the need for withdrawing a sample into a sample cell or into an ex-situ arrangement. The device can be inserted into a port of the bioreactor and provides a sample detection region defined by an optical element such as a lens and a photodetector. The electrical signal obtained from a photodetector that is part of the device can be directed to an analyzer via a detachable electrical connection.

Systems and methods for identifying a cell suspension with therapeutic potential for skin regeneration and related compositions are disclosed herein. In some variations, a method may include receiving a cell suspension that comprises a population of viable cells and non-viable cells, then measuring a value indicative of at least one characteristic of the cell suspension, such as but not limited to one or more of total cell count, total cell viability, cell viability percentage, and median live cell diameter. A cell suspension composition having therapeutic potential may comprise a cell suspension met certain thresholds relating to total cell count, total viable cell count, cell viability percentage, and median live cell diameter.