A system for characterizing at least one particle from a fluid sample is disclosed. The system includes a filter disposed upstream of an outlet, and a luminaire configured to illuminate the at least one particle at an oblique angle. An imaging device is configured to capture and process images of the illuminated at least one particle as it rests on the filter for characterizing the at least one particle. A system for characterizing at least one particle using bright field illumination is also disclosed. A method for characterizing particulates in a fluid sample using at least one of oblique angle and bright field illumination is also disclosed.

A flow-type field-flow fractionation apparatus 1 includes a first heater 14 and a second heater 16. The first heater 14 heats a carrier fluid between a first pump 12 and a separation cell 3. The second heater 16 heats a focus fluid between a second pump 15 and the separation cell 3. Thus, the carrier fluid heated by the first heater 14 is sent by the first pump 12 and flows into the separation cell 3, and the focus fluid heated by the second heater 16 is sent by the second pump 15 and flows into the separation cell 3. This can stabilize temperatures of the carrier fluid and the focus fluid flowing into the separation cell 3. Then, when an analysis is performed using the flow-type field-flow fractionation apparatus 1, the analysis can be performed with high reproducibility.

According to an aspect of an embodiment, a fine dust measurement module includes a fluid inlet into which fluid including fine dust with particles of various diameters is flowed, a first channel through which, of the fine dust introduced through the fluid inlet, first fine dust with particles having a diameter greater than or equal to a first diameter passes, a second channel through which, of the fine dust introduced through the fluid inlet, second fine dust with particles having a diameter less than the first diameter passes, a flow ratio control nozzle arranged in the first channel and configured to control a flow ratio between fluid flowing into the first channel and fluid flowing into the second channel, and a fine dust sensor configured to sense fine dust flowing into the second channel.

A system for characterizing at least one particle from a fluid sample is disclosed. The system includes a filter disposed upstream of an outlet, and a luminaire configured to illuminate the at least one particle at an oblique angle. An imaging device is configured to capture and process images of the illuminated at least one particle as it rests on the filter for characterizing the at least one particle. A system for characterizing at least one particle using bright field illumination is also disclosed. A method for characterizing particulates in a fluid sample using at least one of oblique angle and bright field illumination is also disclosed.

The present disclosure provides apparatuses, systems, and methods for performing particle analysis through flow cytometry at comparatively high event rates and for gathering high resolution images of particles.

A cell capture system including an array, an inlet manifold, and an outlet manifold. The array includes a plurality of parallel pores, each pore including a chamber and a pore channel, an inlet channel fluidly connected to the chambers of the pores; an outlet channel fluidly connected to the pore channels of the pores. The inlet manifold is fluidly connected to the inlet channel, and the outlet channel is fluidly connected to the outlet channel. A cell removal tool is also disclosed, wherein the cell removal tool is configured to remove a captured cell from a pore chamber.

The present invention discloses a simulation device for characterizing aerodynamics of dry powder inhalation in respiratory system comprising: a constant temperature-and-humidity chamber, a steam and vacuum generating device and a respiratory system model arranged in the constant temperature and humidity chamber, and the constant temperature and humidity chamber and the respiratory system model are both connected with the steam and vacuum generating device; a temperature and humidity sensor is arranged in the constant temperature-and-humidity chamber and electrically connected with the steam and vacuum generating device; the respiratory system model comprises an oral cavity receiver and sample collectors, wherein inner walls of the respiratory system model are coated with a coating, the sample collectors includes a first sample collector and a second sample collector, each of the collectors is provided with 8 collecting trays.

A particle sensing device is disclosed for sensing particles entrained in a gas, distribution of particle sizes including a first size range (e.g. PM2.5) and a second size range (e.g. PM10), larger than the first size range. A thermophoretic impulse is applied to the entrained particles. The device has a a first sensor, downstream of the thermophoretic impulse region. The thermophoretic impulse, the flow of gas and gravity combine to cause at least some of the particles to follow respective trajectories within the sampling volume. An interception unit is interposed between the thermophoretic impulse region and the first sensor, to intercept the respective trajectories of particles of the second size range but not respective trajectories of particles of the first size range. The first sensor is located to intercept and detect the respective trajectories of particles of the first size range.

Microfluidic structures and methods for manipulating fluids, fluid components, and reactions are provided. In one aspect, such structures and methods can allow production of droplets of a precise volume, which can be stored/maintained at precise regions of the device. In another aspect, microfluidic structures and methods described herein are designed for containing and positioning components in an arrangement such that the components can be manipulated and then tracked even after manipulation. For example, cells may be constrained in an arrangement in microfluidic structures described herein to facilitate tracking during their growth and/or after they multiply.

Microfluidic devices that are configured to use centrifugal forces to bias particles into one or more capture regions based on their individual sizes are described.