Apparatus and methods for determining particle size, and optionally, the complex index of refraction for particle suspended in a gas or liquid are provided. The particle to be analyzed is caused to travel through a laser beam having a modified Gaussian profile. The particle causes light from the laser beam to scatter. The scattered light is measured by one or more photodetectors disposed at a particular scattering angle relative to the center of the laser beam. The apparatus and methods can be used in sensors configured to monitor air quality in enclosed environments, such as on-board aircraft and within buildings, and/or detect environmental contaminants.

To provide a microparticle measurement technology capable of supporting excitation light in a wideband wavelength range.

The present technology provides a microparticle measurement device provided with a plurality of objective lenses for excitation light irradiation used for irradiating microparticles flowing through a flow path with excitation light, in which at least one of the objective lenses for excitation light irradiation is used for detecting scattered light emitted from the microparticles by the excitation light with which the microparticles are irradiated through another one of the objective lenses for excitation light irradiation.

The present invention relates to an automatic real-time label-free holography-activated sorting of the cell's technique. The technique provides high-discriminative power on the level of the individual cell. The technique includes rapid automated cell processing during cell visualization and flow, with high discriminative power on the level of the individual cell. The technique may be useful in detection of cancer and to identify different stages of oncogenesis.

In one example in accordance with the present disclosure, a system is described. The system includes a fluidic die to advance across an ejection path relative to a substrate. The fluidic die includes a channel to contain a portion of a sample fluid, a sensor to detect passage of a particle within the sample fluid into the channel, and an ejection device. The ejection device is to eject the particle. The system also includes a controller. The controller identifies discrete locations along the ejection path as waste sites as the fluidic die advances along the ejection path. This is done by 1) classifying the particle as a target particle or a non-target particle, 2) upon identification of a target particle, ejecting the target particle to a target site of the substrate, and 3) upon identification of a non-target particle, ejecting the non-target particle to a waste site.

The present disclosure provides an integrated collection, filtration, and analysis system which is configured to automatically collect fluid samples from a surrounding open water environment, isolate floating particles of a target size range, and perform analysis on the collected particles in-situ. The particles may also be filtered by one or more parameters other than size, and also provided herein is a two-stage vortex filter specially adapted to isolate floating particles of a desired density range from a fluid.

The present disclosure provides a random particle generation method based on particle size distribution, which can accord with the particle size distribution characteristics of a geological structure. According to this method, random particle generation is adopted, so that a common spherical structure is avoided, and a generated particle structure is very similar to a real soil structure. Based on actual particle size distribution, particles with different particle sizes are generated by batch generation, particle seeds are generated at random pore locations, and particles are generated based on the seeds. By providing a random particle generation method based on particle size distribution, a soil structure in a form of porous media can be restored by means of simulation, which thus provides a porous medium model for the research of groundwater infiltration and fossil energy exploitation.

Embodiments of apparatus and methods for counting cells in a liquid sample are provided herein. In some embodiments, an apparatus for counting cells in a liquid sample includes: a flow-splitting chamber fluidly coupled to a collection chamber; an input tube configured to deliver a liquid sample to the flow-splitting chamber; a spaced apart array of posts along a flow path configured to redirect the liquid sample into a plurality of streams; a plurality of sensing zones corresponding to the plurality of streams; and a plurality of sensing electrodes, wherein each sensing electrode is disposed in a corresponding sensing zone of the plurality of sensing zones and configured to detect a change in electrical impedance as the liquid sample flows through the plurality of sensing zones.

A microorganism screening system includes a container configured to store a liquid containing microorganism particles and a liquid medium, and a microorganism separation device. The microorganism separation device includes a hydrodynamic separation device and a liquid feeding unit configured to supply the liquid from the container to the hydrodynamic separation device. The hydrodynamic separation device includes a curved flow channel having a rectangular cross-section, and is configured to separate the liquid into a first segment containing relatively large microorganism particles and a second segment containing relatively small microorganism particles through use of a vortex flow generated in the liquid flowing through the curved flow channel. Screening for microorganisms can be performed efficiently.

The present disclosure describes a computer implemented method, a system, and a computer program product of purifying a sample solution via real-time multi-angle light scattering. In an embodiment, the method, system, and computer program product include receiving from a MALS instrument baseline scattering intensity values of a pure buffer, receiving from the MALS instrument scattering intensity values of a sample solution, and characterizing at least one component of the sample solution, resulting in a time series of values of a dimension, D, of the at least one component and a time series of values of excess Rayleigh ratio, R0, of the at least one component, and determining that the values of the dimension, D, fall within a dimension, D, value range and that the values of excess Rayleigh ratio, R0, fall within an excess Rayleigh ratio value range, and transmitting a collect sample solution command to collect the sample solution.

A system and methods of tracking and identifying airborne particles using sensing devices that may include a fan and a collection plate. The fan forces air through the sensing device and airborne particles onto the collection plate. An imaging device captures images of the particles on the collection plate for analysis and identification. An image processing device determines pre-identified particles in the images. The images of other particles are processed and identified by a neural network processing device. Recommendations based on particle counts are provided to a user device. The user device may automatically control one or more devices in response to the recommendations.