A system is provided comprising an FTIR spectrometer configured to obtain a Fourier Transformed infrared (FTIR) spectrum of a Peripheral Blood Mononuclear Cells (PBMC) sample of the subject; a data processor operable with the FTIR spectrometer, and configured to analyze the infrared (IR) spectrum of the Peripheral Blood Mononuclear Cells (PBMC) sample of the subject by assessing a characteristic of the sample of the subject at at least one wavenumber; and an output unit, configured to generate an output indicative of the presence of a solid tumor, based on the infrared (IR) spectrum. Other embodiments are also provided.

Disclosed herein are platforms, systems, and methods including a cell culture system that includes a cell culture container comprising a cell culture, the cell culture receiving input cells, a cell imaging subsystem configured to acquire images of the cell culture, a computing subsystem configured to perform a cell culture process on the cell culture according to the images acquired by the cell imaging subsystem, and a cell editing subsystem configured to edit the cell culture to produce output cell products according to the cell culture process.

An image display method includes the following operations (a) to (e). The (a) is of obtaining a plurality of two-dimensional images by two-dimensionally imaging a specimen, in which a plurality of objects to be observed are present three-dimensionally in the specimen, at a plurality of mutually different focus positions. The (b) is of obtaining image data representing a three-dimensional shape of the specimen. The (c) is of obtaining a three-dimensional image of the specimen based on the image data. The (d) is of obtaining the two-dimensional image selected from the plurality of two-dimensional images or a two-dimensional image generated to be focused on the plurality of objects based on the plurality of two-dimensional images as an integration two-dimensional image. The (e) is of integrating the integration two-dimensional image obtained in the (d) with the three-dimensional image obtained in the (c) and displaying an integrated image on a display unit.

To provide an information processing apparatus and an information processing method capable of easily calculating an error amount included in a measurement value. An information processing apparatus includes: an extraction unit configured to extract each parameter variation that affects fluorescence intensity that is measured when a particle is irradiated with a light beam, from a database on the basis of a measurement condition; and a computation unit configured to generate a calculation formula representing an error amount included in the fluorescence intensity on the basis of the extracted each parameter variation.

A microfluidic chip configuration wherein injection occurs in an upwards vertical direction, and fluid vessels are located below the chip in order to minimize particle settling before and at the analysis portion of the chip's channels. The input and fluid flow up through the bottom of the chip, in one aspect using a manifold, which avoids orthogonal re-orientation of fluid dynamics. The contents of the vial are located below the chip and pumped upwards and vertically directly into the first channel of the chip. A long channel extends from the bottom of the chip to near the top of the chip. Then the channel takes a short horizontal turn that nearly negates any influence of cell settling due to gravity and zero flow velocity at the walls. The fluid is pumped up to a horizontal analysis portion that is the highest channel/fluidic point in the chip and thus close to the top of the chip, which results in clearer imaging. A laser may also suspend cells or particles in this channel during analysis which prevents them from settling.

It is aimed to provide a technology that enables highly accurate device performance evaluation and device adjustment in optical analysis of microparticles, using the same type of beads. The present technology provides an information processing device including an information processing unit that acquires a plurality of fluorescence intensities at a plurality of light irradiation powers for a fluorescence signal from a sample including particles labeled with a fluorescent dye having a single fluorescence intensity, recognizes an intensity range of each of the plurality of fluorescence intensities detected on the basis of a fluorescence intensity balance of the sample, and calculates information relating to sensitivity of a fluorescence detection unit.

The present invention relates to compositions comprising magnetic particles, the methods of using these compositions in processing animal sperm, the resulting sperm and embryo products, and the methods of use of these compositions to increase the efficiency, efficacy and/or speed of cell processing and artificial insemination techniques.

A system and method for automated testing a sample of a body fluid for the presence of bacteria is described. The system includes a fluid handling device, Incubator, flow cytometer, at least a processor, and a memory configuring the at least a processor to distribute a portion of the plurality of fluid samples within a well plate to at least a first well, divide the portion of the plurality of fluid samples from the at least a first well into at least two wells including a T.sub.0 well and a T.sub.1 well, obtain a T.sub.0 enumerative baseline bacterial value at time T.sub.0, culture the fluid samples in the T.sub.1 well using the incubator, obtain a T.sub.1 enumerative control bacterial value at time T.sub.1, and determine a presence of bacteria as a function of the T.sub.0 enumerative baseline bacterial value and the T.sub.1 enumerative control bacterial value.

Disclosed herein include embodiments of a system, a device, and a method for sorting a plurality cells of a sample. A plurality of raw images comprising pixels of complex values in a frequency space can be generated from a plurality of channels of fluorescence intensity data of fluorescence emissions of fluorophores, the fluorescence emissions being elicited by fluorescence imaging using radiofrequency-multiplexed excitation in a temporal space. Spectral unmixing can be performed on the raw images prior to a sorting decision being made.

The present invention provides self-contained systems for performing an assay for determining a chemical state, the system including a stationary cartridge for performing the assay therein, at least one reagent adapted to react with a sample; and at least one reporter functionality adapted to report a reaction of the at least one reagent with said sample to report a result of the assay, wherein the at least one reagent, the sample and the at least one reporter functionality are contained within the cartridge.