A particle sensor apparatus having an optical emitter device that is configured to emit an optical radiation so that a volume having at least one particle possibly present therein is at least partly illuminatable; an optical detector device having at least one detection surface that is struck by at least a portion of the optical radiation scattered at the at least one particle, at least one information signal regarding an intensity and/or an intensity distribution of the optical radiation striking the at least one detection surface being outputtable; and an evaluation device with which an information item regarding a presence of particles, a number of particles, a particle density, and/or at least one property of particles is identifiable and outputtable, the particle sensor apparatus also encompassing at least one lens element that is disposed so that the emitted optical radiation is focusable onto a focus region inside the volume.

A microfluidic multiple channel particle analysis system which allows particles from a plurality of particle sources to be independently simultaneously entrained in a corresponding plurality of fluid streams for analysis and sorting into particle subpopulations based upon one or more particle characteristics.

Systems and methods are provided for determining a velocity or an inflation rate of a droplet in a microfluidic channel. The droplet is exposed to two or more temporally separated flashes of light, each flash including light of one wavelength band, and imaged using a detector configured to distinguish light in the wavelength bands. Two or more images of the droplet are acquired, each corresponding to one of the flashes, and all within a single video frame or photographic exposure. The images can be processed separately and the position or size of the droplet in each image is calculated. A velocity or inflation rate is then determined by dividing the change in position or size by the amount of time allowed to pass between the flashes.

An apparatus for generating high voltage (HV) driving signals associated with an ion mobility detector comprises a ground-based HV base module and a HV deck module coupled by an interconnect module. The HV base module implements dual power supplies that together drive a drift tube voltage signal to the high-voltage-based deck module. Each of the power supplies is regulated by a combination open loop and closed loop controller. The HV deck module implements one or more grid modules that generate a bipolar voltage that floats on the drift tube voltage signal. Also included may be a pulse generator configured to generate at least one synchronizing timing pulse. Power supplies within the apparatus may be synchronized based on the synchronization timing pulse.

Disclosed is an apparatus and method for providing asymmetric oscillations to a container. The container may include a fluid, a particle, and/or a gas. A vibration driver attached to the container provides asymmetric oscillations. A controller connected to the vibration driver controls an amplitude, frequency, and shape of the asymmetric oscillations. An amplifier amplifies the asymmetric oscillations in response to the controller. A sensor disposed on the vibration driver provides feedback to the controller.

A gaseous-fluid environmental sensor having a gaseous-fluid flow system. The gaseous-fluid flow system includes a blower to move the gaseous fluid from a inlet intake port to an outlet exhaust port via a flow path. The blower includes a motor, which can have a fluid dynamic bearing. The gaseous-fluid environmental sensor further includes a flow sensor to sense a parameter relating to a flow of the gaseous fluid through the flow path and provide a signal based on the parameter, and a controller coupled to the flow sensor. The controller controls the blower based on the signal.

A self-mixing interferometer configured to monitor particulate material within a monitored region of space comprising a laser cavity assembly (1A) and an optical assembly (1B) configured to bathe the monitored region with laser light of the interferometer possessing wavefronts having different directions at different respective locations within the monitored region. A laser monitoring unit (1C) is configured to acquire an interferometric signal generated by the interferometer in response to light returned to the laser cavity assembly from said wavefronts by said particulate material. A processing module (1D) is configured to determine a property of the particulate material within the monitored region according to changes in the frequency of a waveform within at least a part of the interferometric signal.

A microfluidic impedance cytometry apparatus, for position determination and impedance measurement of particle/s in a fluid carrying particles, comprising: a microfluidic impedance flow channel for allowing flow of said fluid; an upstream section; a downstream section; a sensing region to receive said channeled fluid, to sense one or more parameters of said fluid, said sensing region comprising one or more sets of pairs of electrodes, each pair forming a current path from an operative top to an operative bottom, each of said pairs being formed by an operative top electrode and an operative bottom electrode, electric potential being applied on said operative top electrode/s, each electrode for a particular pair being parallel-aligned and being symmetric, with respect to each other, same positive electric potential being applied on each of said top electrodes and each of said bottom electrodes is virtually grounded, for a pair; and a configuration of amplifiers.

A microfluidic apparatus includes a microfluidic chip for MicroOrganoSpheres (MOS) generation. A first channel is defined in a surface of the microfluidic chip and includes: a droplet generation portion including an inlet portion, a junction between the inlet portion and an emulsifying fluid channel, and a chamber downstream of the junction. A cross-sectional area of the chamber is larger than that of the inlet portion. The first channel includes a polymerization portion downstream of the droplet generation portion, the polymerization portion having a serpentine configuration. The apparatus includes a cartridge for MOS demulsification, including: a collection container; a substrate disposed on the collection container, and a membrane disposed between the collection container and the surface of the substrate. A second channel is defined in the surface of the substrate that faces the collection container and is fluidically connected to an output of the polymerization portion of the first channel.

A droplet detection system includes a sensing channel, such as a microfluidic channel, configured to receive a flow of fluid that may contain one or more liquid droplets dispersed in the fluid. The cross-sectional area of the sensing channel maybe configured to allow droplets of a predetermined size to flow through the channel one at a time. A light source, a light aperture, and a light detector are positioned outside the sensing channel, which use light in a selected frequency band that has a substantially different absorbance for the liquid compared to the fluid. Liquid droplets may be detected and characterized using a signal from the light detector.