G01N21/03

Methods and apparatus for determining characteristics of particles from scattered light
11513047 · 2022-11-29 ·

The present invention comprises methods and apparatus utilizing multiple detectors to measure properties related to light scattered by particles. Characteristics of particles are determined from the measured properties.

Absorption analyzer
11513060 · 2022-11-29 · ·

In order to provide an absorption analyzer capable of directly measuring an analysis target gas flowing into or produced in a vessel such as a chamber and preventing a measurement error due to moisture condensation, the absorption analyzer is adapted to include: a light emission module that is attached covering a first opening of the vessel into which the analysis target gas flows or in which the analysis target gas is produced and emits light into the vessel; and a light detection module that detects the light emitted from the light emission module and passing through the vessel. In addition, the light emission module is adapted to include: a base flange that is attached around the first opening on an outer surface of the vessel; a window material whose outer surface is tilted at a predetermined angle; a seal member; and a pressing body.

IN VITRO DIAGNOSTIC APPARATUS

The present invention relates to an automatic in vitro diagnostic apparatus capable of automatically performing a series of examination processes including a pretreatment process for specific components included in a biological sample such as blood and urine. The apparatus of the present invention comprises a base frame 104; a cuvette tray 110 movable back and forth on the base frame 104, for mounting cuvette holders 10 accommodating a plurality of cuvettes arranged thereon alongside each other; a tube tray 120 movable back and forth on the base frame, for mounting tube holders 20 accommodating a plurality of sample tubes containing samples thereon; and a sampling operation unit 500 movable left and right on the base frame 104, for mixing a sample contained in the sample tube with a reagent, and dropping the mixed solution onto an analysis strip provided in the cuvette.

IN VITRO DIAGNOSTIC APPARATUS

The present invention relates to an automatic in vitro diagnostic apparatus capable of automatically performing a series of examination processes including a pretreatment process for specific components included in a biological sample such as blood and urine. The apparatus of the present invention comprises a base frame 104; a cuvette tray 110 movable back and forth on the base frame 104, for mounting cuvette holders 10 accommodating a plurality of cuvettes arranged thereon alongside each other; a tube tray 120 movable back and forth on the base frame, for mounting tube holders 20 accommodating a plurality of sample tubes containing samples thereon; and a sampling operation unit 500 movable left and right on the base frame 104, for mixing a sample contained in the sample tube with a reagent, and dropping the mixed solution onto an analysis strip provided in the cuvette.

Optical sensors for monitoring biopharmaceutical solutions in single-use containers
11506597 · 2022-11-22 · ·

Disposable, pre-sterilized, and pre-calibrated, pre-validated sensor components are provided. The sensor components interact with a sensor system having disposable fluid conduit or bioreactor bag and a reusable sensor assembly. The components can include an optical bench or inset optical component or module designed to be integrated within the disposable fluid conduit or bioreactor bag, which provides an optical light path through the conduit or bag. The sensors systems are designed to store sensor-specific information, such as calibration and production information, in a non-volatile memory chip on the disposable fluid conduit or bag and on the reusable sensor assembly. Methods for calibrating the sensor and for determining a target property of an unknown fluid are also disclosed. The devices, systems and methods relating to the sensor are suitable for and can be outfitted for turbidity sensing.

Method for analyzing and selecting a specific droplet among a plurality of droplets and associated apparatus

The present invention relates to a method for analyzing and selecting a specific droplet among a plurality of droplets (4), comprising the following steps: —providing a plurality of droplets (4), —for a droplet (4) among the plurality of droplets, measuring at least two optical signals, each optical signal being representative of a light intensity spatial distribution in the droplet for an associated wavelength channel, —calculating a plurality of parameters from the optical signals, —determining a sorting class for a droplet according to calculated parameters, —sorting said droplet according to its sorting class, wherein the plurality of parameters comprises the coordinates of a maximum for each optical signal and a co-localization parameter and the at least two calculated parameters used for the determining step comprises the co-localization parameter.

OPERANDO CHEMICAL AND/OR ELECTROCHEMICAL TESTING CELL
20230055246 · 2023-02-23 ·

A test cell for operando testing comprises: a housing assembly defining at least a portion of an inner chamber; a window coupled to said housing assembly and defining another portion of the inner chamber; and at least one port for accommodating an electrode and/or conductive wire in communication with the inner chamber. The inner chamber is configured for receiving one or more samples undergoing a chemical and/or electrochemical reaction therein. The port is sealable to hermetically seal the inner chamber.

Kits and devices for detecting analytes

The invention provides devices that improve tests for detecting specific cellular, viral, and molecular targets in clinical, industrial, or environmental samples. The invention permits efficient detection of individual microscopic targets at low magnification for highly sensitive testing. The invention does not require washing steps and thus allows sensitive and specific detection while simplifying manual operation and lowering costs and complexity in automated operation. In short, the invention provides devices that can deliver rapid, accurate, and quantitative, easy-to-use, and cost-effective tests.

Kits and devices for detecting analytes

The invention provides devices that improve tests for detecting specific cellular, viral, and molecular targets in clinical, industrial, or environmental samples. The invention permits efficient detection of individual microscopic targets at low magnification for highly sensitive testing. The invention does not require washing steps and thus allows sensitive and specific detection while simplifying manual operation and lowering costs and complexity in automated operation. In short, the invention provides devices that can deliver rapid, accurate, and quantitative, easy-to-use, and cost-effective tests.

Hazardous contaminant collection kit and rapid testing

Contamination detection systems, kits, and techniques are described for testing surfaces for the presence of hazardous contaminants, while minimizing user exposure to these contaminants. Even trace amounts of contaminants can be detected. A collection kit provides a swab that is simple to use, easy to hold and grip, allows the user to swab large areas of a surface, and keeps the user's hands away from the surface being tested. The kit also provides open and closed fluid transfer mechanism to transfer the collected fluid to a detection device while minimizing user exposure to hazardous contaminants in the collected fluid. Contamination detection kits can rapidly collect and detect hazardous drugs, including trace amounts of antineoplastic agents, in healthcare settings at the site of contamination.