An apparatus for measuring the absorbance of a substance in a solution includes at least one sample cell arranged to contain the solution that is at least partially transparent to light of a predefined wavelength spectrum, at least two light passages through the at least one sample cell, each of the light passages having a known path length, an LED light source arrangement including at least two LEDs, each arranged to emit a light output with a wavelength within the predefined wavelength spectrum. A plurality of optical fibers, one for each light passage, is arranged at each LED for receiving the light output and guiding it to the light passages. A method for measuring the absorbance of a substance in a solution includes providing the LED light source arrangement with an associate fiber bundle for each LED.

A determination method includes: using a microchip, including a capillary flow path and a sample reservoir connected to the capillary flow path at an upstream side, to fill the capillary flow path with a first solution for electrophoresis, and supply the sample reservoir with a second solution containing an analyte; applying a voltage between the sample reservoir supplied with the second solution and the inside of the capillary flow path filled with the first solution, to move a component contained in the second solution in the capillary flow path and separate the component in the capillary flow path; optically detecting a value related to a component difference between the first solution and the second solution, other than a value related to the analyte, for the separated component; and determining whether the optical detection is favorable or poor by comparing the optically detected value with a predetermined threshold value.

Spectrophotometric measurements on highly absorbing turbid samples face technical challenges that can be solved by reducing a path length of an optical chamber used during measurement. Reducing the path length requires exceptional control of variables that may be difficult to achieve in unit-use and inexpensive cuvettes. The invention provides a precise inexpensive method for producing an optical cavity useful in making spectrophotometric measurements on high attenuation liquid samples. Two components are shaped such that, when in contact, a central optical chamber and peripheral groove are formed. Liquid adhesive dispensed into the groove wicks around the interface perimeter, sealing the components together when cured. This results in a short precisely controlled path length that reduces chances of mechanical induced distortions (that arise with other bonding methods). The invention provides for manufacturing of a consistent optical chamber with very short path length within a diagnostic cartridge or cuvette.

An object of the present disclosure is to provide a technique capable of acquiring an analysis target region and color information without causing a decrease in extraction accuracy of the analysis target region due to erroneous extraction of a color of a colored label, measuring a solution volume of the specimen, and determining a specimen type. The biological specimen analysis device according to the present disclosure creates a developed view by cutting out a partial region from a color image of a biological sample tube and connecting the partial region along a circumferential direction of the biological sample tube, and extracts a detection target region from the developed view (see FIG. 6B).

An object of the present disclosure is to provide a technique capable of acquiring an analysis target region and color information without causing a decrease in extraction accuracy of the analysis target region due to erroneous extraction of a color of a colored label, measuring a solution volume of the specimen, and determining a specimen type. The biological specimen analysis device according to the present disclosure creates a developed view by cutting out a partial region from a color image of a biological sample tube and connecting the partial region along a circumferential direction of the biological sample tube, and extracts a detection target region from the developed view (see FIG. 6B).

In an embodiment, an apparatus (100) is described. The apparatus comprises an infrared, IR, generating system (102). The IR generating system comprises a first IR source (104) configured to produce IR radiation for forming a first IR beam (106) in a first spectral band. The IR generating system further comprises a second IR source (108) configured to produce IR radiation for forming a second IR beam (110) in a second spectral band. The apparatus further comprises a beam manipulation system (112) configured to combine a beam path of the first and second IR beams and direct the first and second IR beams along the beam path through a gas sample region (114). The apparatus further comprises an IR detection system (116) configured to detect an intensity of the first and second IR beams after passage through the gas sample region. The IR detection system is configured to produce a signal (118) from which an indication of a concentration of a target gas in the gas sample region can be derived.

The invention concerns sensors (1) for detection of gas, in particular sensors for detection of transcutaneous gas such as CO.sub.2, and methods for manufacturing a sensor (1). The sensor (1) comprises at least one radiation source (3) for emitting radiation, at least one detector (4) for detection of radiation emitted by the radiation source (3), and at least one measurement chamber (6) for receiving the sample gas. The radiation source (3), the detector (4), and the measurement chamber (6) are arranged such that at least a part of the radiation propagates along a path passing through the measurement chamber (6). The sensor (1) further comprises a casing (7), wherein the radiation source (3), the detector (4), the measurement chamber (6) are arranged. The sensor (1) has a contact face (8) which is directable towards a measuring site and the sensor (1) has at least one gas-access channel (9) enabling gas to migrate from the contact face (8) into the measurement chamber (6). The casing (7) comprises a, preferably metallic, material having a high thermal conductivity, preferably more than 10 W/m/K.

The disclosure relates to a method of culturing and analyzing at least one cell in a microchamber configured to allow for optical inspection of the at least one cell, wherein liquid is extracted from the microchamber for analysis, characterized in that the analysis returns information about particles secreted from the at least one cell and that this information can be correlated to the individual cell and/or cell population. The disclosure further relates to a device for use in the method and a system and a computer program for performing one or more of the steps of the method.

The disclosure relates to a method of culturing and analyzing at least one cell in a microchamber configured to allow for optical inspection of the at least one cell, wherein liquid is extracted from the microchamber for analysis, characterized in that the analysis returns information about particles secreted from the at least one cell and that this information can be correlated to the individual cell and/or cell population. The disclosure further relates to a device for use in the method and a system and a computer program for performing one or more of the steps of the method.

A fire detection apparatus 1A includes a detector cover 70A for inhibiting ambient light from entering a detection space 60A, an inner cover 30A that accommodates the detection space 60A and the detector cover 70A, an outer cover 20A that accommodates the inner cover 30A, a first opening 30aA provided in a side portion on an opposite side from a side portion on an installation surface side among side portions of the inner cover 30A, a second opening provided in a side portion on an opposite side from a side portion on an installation surface among side portions of the detector cover 70A, and a flat plate-shaped insect screen 50A provided on the detector cover 70A and configured to substantially cover the entire second opening.