An analysis device 1 is provided with: a flow channel 12c; a suction mechanism connected to one end of the flow channel, the suction mechanism being configured to introduce a trace amount of a liquid sample L from the other end of the flow channel 12c into an inside of the flow channel 12c and hold the liquid sample L in a part of the flow channel 12c; and a measurement unit 40 configured such that a light irradiation unit 41 for irradiating the liquid sample L held by the part of the flow channel member 12 with light and a light reception unit for receiving the light from the liquid sample L are disposed around the liquid sample L. The measurement unit 40 is provided with an aperture member 46 to limit the light directed from the light irradiation unit 41 toward the liquid sample L, the aperture member 46 including an opening having an opening width L2 shorter than a liquid length L1 of the liquid sample L held by the flow channel 12c in the flow channel 12c.

A plasmon resonance (PR) system, instrument, and/or device and configurations thereof for measuring molecular interactions is disclosed. In some embodiments, the PR system, instrument, and/or device is a localized surface plasmon resonance (LSPR) system, instrument, and/or device. In other embodiments, the PR system, instrument, and/or device is a surface plasmon resonance (SPR) system, instrument. The PR system, instrument, and/or device may include, for example, force feedback for reliable flow cell sealing, optical feedback for reliable flow cell sealing, local thermal control of an LSPR chip (e.g., a ring Peltier, a continuous Peltier), dual displacement pumps for constant flow delivery to a microfluidic device, a dual channel LSPR sensor, and any combinations thereof.

A system and a method for automated sorting and trimming a plant. The system includes a trimming station, adapted to identify undesired portions of the plant, and to trim the undesired portions off the plant. The system may further include a guiding assembly adapted to ensure that the plant is aligned with the trimming station. A controller controls operation of the trimming station and of the guiding assembly. The system may further include a sorting station adapted to determine whether the plant is infected or contaminated. The controller may be adapted to control operation of the sorting station.

An apparatus, system, and method for performing an efficient luminescence measurement are disclosed. The apparatus comprises a nozzle for dispensing a luminescent reagent into a well W in a microplate M, a luminescence measurement unit for measuring luminescence occurring in the well W caused by mixing of the luminescent reagent and a specimen, and a stage (moving unit) for moving the nozzle and the luminescence measurement unit together vertically and horizontally, wherein the nozzle is secured to the stage and the luminescence measurement unit is mounted to be movable vertically with respect to the stage through a holder and springs interposed between the luminescence measurement unit and the holder.

An apparatus, system, and method for performing an efficient luminescence measurement are disclosed. The apparatus comprises a nozzle for dispensing a luminescent reagent into a well W in a microplate M, a luminescence measurement unit for measuring luminescence occurring in the well W caused by mixing of the luminescent reagent and a specimen, and a stage (moving unit) for moving the nozzle and the luminescence measurement unit together vertically and horizontally, wherein the nozzle is secured to the stage and the luminescence measurement unit is mounted to be movable vertically with respect to the stage through a holder and springs interposed between the luminescence measurement unit and the holder.

According to various embodiments, a method is provided that comprises washing an array of DNA-coated beads on a substrate, with a wash solution to remove stacked beads from the substrate. The wash solution can include inert solid beads in a carrier. The DNA-coated beads can have an average diameter and the solid beads in the wash solution can have an average diameter that is at least twice the diameter of the DNA-coated beads. The washing can form dislodged DNA-coated beads and a monolayer of DNA-coated beads. In some embodiments, first beads for forming an array are contacted with a poly(ethylene glycol) (PEG) solution comprising a PEG having a molecular weight of about 350 Da or less. In some embodiments, slides for forming bead arrays are provided as are systems for imaging the same.

According to various embodiments, a method is provided that comprises washing an array of DNA-coated beads on a substrate, with a wash solution to remove stacked beads from the substrate. The wash solution can include inert solid beads in a carrier. The DNA-coated beads can have an average diameter and the solid beads in the wash solution can have an average diameter that is at least twice the diameter of the DNA-coated beads. The washing can form dislodged DNA-coated beads and a monolayer of DNA-coated beads. In some embodiments, first beads for forming an array are contacted with a poly(ethylene glycol) (PEG) solution comprising a PEG having a molecular weight of about 350 Da or less. In some embodiments, slides for forming bead arrays are provided as are systems for imaging the same.

Provided are methods, devices, assemblies, and systems for dispensing into the wells of a multi-well device and imaging such wells from multiple Z-planes. Multi-Z imaging of the present methods and systems may allow for the detection of wells of a multi-well device that contain a desired number of cells. Also provided are methods, devices, assemblies, and systems for processing cell-containing wells of a multi-well device identified through the use of multi-Z imaging.

A device for light-based analysis of a substance in a liquid sample comprises: an analysis cell for holding the liquid sample; wherein the analysis cell comprises a first wall portion for passing light generated by a light source into the analysis cell, and a second wall portion for passing light from the analysis cell to a light detector; and a plunger configured for movement along walls of the analysis cell for allowing entry of the liquid sample into the analysis cell and pushing the liquid sample out of the analysis cell; wherein at least one wiper is arranged on the plunger for cleaning the first and second wall portions during movement of the plunger.

A device for light-based analysis of a substance in a liquid sample comprises: an analysis cell for holding the liquid sample during analysis; a plunger configured for movement along walls of the analysis cell for allowing entry of the liquid sample into the analysis cell and pushing the liquid sample out of the analysis cell, wherein a first analysis measurement is allowed to be performed while a second portion of the plunger is arranged between a light source and a light detector; wherein the plunger is movable to a completely retracted position in the analysis cell for allowing a second analysis measurement to be performed such that light being detected by the light detector is passed through the liquid sample filling a space between opposite walls of the analysis cell.