G01N2021/1765

TRANSPARENCY EVALUATION METHOD

A transparency assessment method includes: a step of acquiring N frequency distributions for a target color in N predetermined regions in a plate image, the N frequency distributions having at least two color feature quantities as variates; and a step of assessing transparency based on a first reference frequency distribution for a first reference target color which is a target color of a first transparent state, and based on the N frequency distributions. The plate image corresponds to an assessment plate in which an assessment target includes a tester is held in a plurality of wells. The plurality of wells have at least one test substance well that holds the assessment target including the tester. The transparency is assessed based on a centroid vector directed from a centroid position of a first reference target color region toward a centroid position of a target color region in the N frequency distributions.

Androgen receptor variant-based prostate cancer patient screening method
11789023 · 2023-10-17 · ·

A method for screening a prostate cancer patient, which may analyze whether or not androgen receptor (AR)-targeted therapy is applicable to the prostate cancer patient, through optical image analysis of circulating tumor cells and an AR variant.

MICROORGANISM INFORMATION PROVIDING DEVICE AND METHOD
20210340591 · 2021-11-04 ·

According to an embodiment of the present disclosure, provided is an apparatus for providing microorganism information, including: a receiving unit configured to receive a plurality of images obtained by photographing in time series an outgoing wave emitted from a sample; a detecting unit configured to extract a feature of a change over time from the plurality of images obtained by photographing in time series; a learning unit configured to machine-learn classification criteria based on the extracted feature; and a determining unit configured to classify the type or concentration of a microorganism included in the sample based on the classification criteria, wherein each of the plurality of images includes speckle information generated by multiple scattering by the microorganism due to waves incident on the sample.

OPTICAL NANOSTRUCTURE SENSING DEVICE AND IMAGE ANALYSIS METHOD
20210341386 · 2021-11-04 ·

The present invention relates to an optical nanostructure sensing device and an image analysis method. The image analysis method includes: illuminating a light beam from a predetermined incident angle onto a nanostructure pixel sensor; capturing images of the nanostructure pixel sensor when applying an analyte on the nanostructure pixel sensor; obtaining a relationship of periodic spacing and brightness from each of the images; and obtaining wavelength values from the relationship of periodic spacing and brightness at a predetermined brightness value; and determining a sensing process based on a wavelength shift of the wavelength values. The nanostructure pixel sensor includes a plurality of the nanostructure pixels, each of the nanostructure pixels includes periodic nanostructures, and the relationship of periodic spacing and brightness is based on the brightness of the nanostructure pixels having different periodic spacings.

Laser beam irradiation detection device, laser beam irradiation detection method, and laser beam irradiation detection system

A bandpass filter allows a light ray of a predetermined band including a wavelength band of a color of a laser beam, which is a target of detection, among light rays from a subject to pass therethrough. An imaging unit of a video camera captures the light ray passing through the bandpass filter. The controller analyzes a frequency for each brightness level of a video signal generated based on an imaging signal output from the imaging unit and detects a peak at which the frequency protrudes at a specific brightness level. The controller detects a trajectory of a straight light ray in a frame of the video signal. The controller detects that the laser beam is irradiated when the peak exists at a specific brightness level and the trajectory of the light ray exists in the frame.

CELL ANALYSIS METHOD AND CELL ANALYSIS SYSTEM
20230333016 · 2023-10-19 ·

The cell analysis method includes: a first storage step of storing a first liquid containing a cell in a first tank; a second storage step of storing a second liquid containing a compound in a second tank; a first discharge step of discharging the first liquid to a plurality of portions on a substrate, to thereby form a plurality of first liquid droplets; a second discharge step of discharging the second liquid to the plurality of portions on the substrate in such a manner that the second liquid is allowed to be admixed with the first liquid droplets; a result acquisition step of acquiring results of a reaction between the cell and the compound; and an analysis step of analyzing the results acquired in the result acquisition step to specify a portion in which results satisfying predetermined criteria are obtained among the plurality of portions.

Reconfigurable Integrated Circuits for Adjusting Cell Sorting Classification
20230334883 · 2023-10-19 ·

Aspects of the present disclosure include reconfigurable integrated circuits for characterizing particles of a sample in a flow stream. Reconfigurable integrated circuits according to certain embodiments are programmed to calculate parameters of a particle in a flow stream from detected light; compare the calculated parameters of the particle with parameters of one or more particle classifications; classify the particle based on the comparison between the parameters of the particle classifications and the calculated parameters of the particle; and adjust one or more parameters of the particle classifications based on the calculated parameters of the particle. Methods for characterizing particles in a flow stream with the subject integrated circuits are also described. Systems and integrated circuit devices programmed for practicing the subject methods, such as on a flow cytometer, are also provided.

Under display terahertz biometric imaging arrangement

The present invention relates to a terahertz biometric imaging arrangement configured to be arranged under an at least partially transparent display panel and configured to capture an image of an object located on an opposite side of the transparent display panel, the biometric imaging arrangement comprising: a transmitter element arranged to emit terahertz radiation for illuminating the object; and an image sensor comprising an antenna pixel array arranged to detect terahertz radiation transmitted from the illuminated object, for producing an image.

Single ion detection method and device

A single ion imaging-based detection method and device are provided. After being reflected by an electromodulation singularity coupling differential imaging reaction unit, a probe beam from a total internal reflection ellipsometry imager converges on a CCD or CMOS detector, the acquired sensing surface image data is transmitted to a signal processing unit, the common mode noise is eliminated by performing spectral analysis on differential signals of a working sensing surface and a reference sensing surface, the peak intensity of a modulating signal is selected on the spectrum for wave filtering to obtain a real-time signal of interaction of single ions or charged molecules at a solid-liquid interface. Based on the singularity effect at a surface plasma resonance angle of an ellipsometry phase and a corresponding optical signal noise suppression scheme, the present application can achieve real-time observation of the adsorption of single ions or charged molecules at a solid surface.

METHOD FOR EVALUATING EVALUATION TARGET

A method for evaluating an evaluation target includes: an irradiation step of irradiating an evaluation plate, in which an evaluation target is held in a plurality of wells provided in the evaluation plate, with illumination light from a light source; an imaging step of imaging the evaluation plate while the evaluation plate is irradiated with the illumination light; and an evaluation step of evaluating the evaluation target based on an image of the evaluation plate obtained in the imaging step, in the imaging step, imaging of the whole of the evaluation plate is ended in less than 120 seconds from start of irradiation of the evaluation plate with the illumination light in the irradiation step, and irradiation with the illumination light is ended after end of imaging of the whole of the evaluation plate in the imaging step.