A microscope apparatus includes an illumination optical system that emits activating light and exciting light, an image capturing unit that captures an image formed by an imaging optical system, an image processing unit that carries out image processing using an image capturing result from the image capturing unit, and a controller. The controller provides a plurality of image generation periods and interrupt periods; causes, in the image generation periods, the activated fluorescent material to be irradiated with the exciting light and causes the image capturing unit to capture an image of the fluorescent light from the activated fluorescent material in a plurality of frame periods; and sets an intensity of the exciting light in the interrupt periods to be lower than an intensity in the image generation periods or causes the emission of the exciting light to stop in the interrupt periods. The image processing unit generates one picture image from at least some of image capturing results obtained in the plurality of frame periods.

Systems and methods for optical inspection of a sample are provided. Radiation scattered from the sample includes a first portion having a first polarization state and a second portion having a second polarization state that is a mirror image of the first polarization state. The first polarization state of the first portion of the scattered radiation is transposed using a polarizing mirroring device so that the scattered radiation output from the polarizing mirroring device has substantially the second polarization state.

A multimodal imaging system comprises a light source, an image sensor comprising a plurality of pixels, and an optical filter comprising a first filter element and a second filter element. The light source emits partially coherent polarized light, and the first filter element and second filter element are arranged as an array parallel to the image sensor. The first filter element is configured for attenuated transmission of a first light spectrum, which comprises polarized light emitted by the light source, and the second filter element is configured for transmission of a second light spectrum. The image sensor is configured to simultaneously capture light impinging on the image sensor from both the first filter element and the second filter element. Each filter element of the optical filter is configured for transmission of light to a subset of the imager pixels.

An in-situ gemstone characteristic analysis system, apparatus and method. Included are an in-situ rig comprising a plurality of movable camera sensors, a plurality of stimulus dispensers, and a plurality of environmental condition dispensers; a first input remote from the in-situ rig for receiving output from the camera sensors responsive to applications to a gemstone in the in-situ rig of at least the stimulus and the environmental conditions; a comparator communicative with the first input and having accessible thereto a plurality of gemstone characteristics resultant from substantially similar ones of the stimulus and the environmental conditions, and capable of comparing the output from the camera sensors to the plurality of gemstone characteristics and finding a match, under control from at least one computing processor applying a plurality of machine learning rules; and a match output in a case of the match being within a predetermined threshold.

The present disclosure provides a material identification method and a device based on laser speckle and modal fusion, an electronic device and a non-transitory computer readable storage medium. The method includes: performing data acquisition on an object by using a structured light camera to obtain a color modal image, a depth modal image and an infrared modal image; preprocessing the color modal image, the depth modal image and the infrared modal image; and inputting the color modal image, the depth modal image and the infrared modal image preprocessed into a preset depth neural network for training, to learn a material characteristic from a speckle structure and a coupling relation between color modal and depth modal, to generate a material classification model for classifying materials, and to generate a material prediction result in testing by the material classification model of the object.

Systems and methods for optical inspection of a sample are provided. Radiation scattered from the sample includes a first portion having a first polarization state and a second portion having a second polarization state that is a mirror image of the first polarization state. The first polarization state of the first portion of the scattered radiation is transposed using a polarizing mirroring device so that the scattered radiation output from the polarizing mirroring device has substantially the second polarization state.

A method of detecting a mineral or metal in ground includes capturing an image of a target region of the ground and processing the image to determine a location of a candidate rock or plant of interest that is known to be usable for the detection of a mineral or element of interest. Once located, electromagnetic radiation, such as a laser, is directed to the candidate rock or plant to create a light signature, such as by vaporization. The method analyzes the light signature for the presence of the mineral or metal in the target region and determines if the light signature indicates the mineral or metal is present in the ground. The light signature can be analyzed with a spectroscope to detect the mineral or element as an indication of the present of the mineral or element in the ground around or below the candidate rock or plant.

A biological tissue analyzing device configured to analyze a biological tissue using hyperspectral data in which spectral information is associated with each of pixels forming a two-dimensional image and comprising the following (i) and (ii), as well as comprising (iii) and/or (iv): (i) a hyperspectral data acquisition unit configured to acquire the hyperspectral data; (ii) an analysis target region extraction unit configured to extract pixels corresponding to an analysis target region from a two-dimensional image of the biological tissue; (iii) an altered state classification unit configured to roughly classify an altered state of the biological tissue with unsupervised learning; and (iv) an altered state identification unit configured to identify the altered state of the biological tissue with supervised learning.

Hyperspectral, fluorescence, and laser mapping imaging with reduced fixed pattern noise is disclosed. A method includes actuating an emitter to emit a plurality of pulses of electromagnetic radiation and sensing reflected electromagnetic radiation resulting from the plurality of pulses of electromagnetic radiation with a pixel array of an image sensor. The method includes reducing fixed pattern noise in an exposure frame by subtracting a reference frame from the exposure frame. The method is such that at least a portion of the pulses of electromagnetic radiation emitted by the emitter comprises one or more of: electromagnetic radiation having a wavelength from about 513 nm to about 545 nm, from about 565 nm to about 585 nm, from about 900 nm to about 1000 nm, an excitation wavelength of electromagnetic radiation that causes a reagent to fluoresce, or a laser mapping pattern.

The invention relates to a device (100) and a corresponding method for thermoacoustic sensing, in particular thermoacoustic imaging, the device (100) comprising: a) an irradiation unit (10) configured to generate electromagnetic and/or particle energy exhibiting a first modulation, the first modulation comprising at least one frequency and to continuously emit the energy towards a target (1), whereby acoustic waves are continuously generated in the target, the acoustic waves exhibiting a second modulation, the second modulation comprising the at least one frequency and/or a harmonic frequency of the at least one frequency; b) a detection unit (20) configured to simultaneously detect the acoustic waves exhibiting the second modulation while the energy exhibiting the first modulation is being continuously emitted towards the target (1); and c) a processing unit (30) configured to determine at least one thermoacoustic value of an amplitude and/or a phase of the second modulation of the acoustic waves at the at least one frequency and/or at a harmonic frequency of the at least one frequency. The invention allows for fast and economic thermoacoustic sensing, in particular imaging of a region of interest of an object.