The present patent of invention relates to a reader device for biological samples used in the field of remote laboratory tests (TLR), for clinical diagnostic purposes, based on an optimized design constituted by a cowling (C) with inlet port (OE) and with switch (I); by a holding support (SS) containing a mirror (ES), two batteries (BT), two reading illumination arrays (BIL), operational status illumination arrays (BIS) and an elevator support (SE); by an elevator (EL); by an electronics board (PE) with energy loading circuit (PE-1), with supply circuit (PE-2), with processor (PE-3), with Bluetooth® device (PE-4) and with position sensor (PE-5); and by a base (BA) with software that reads various types of biological samples, the present invention providing the advantages of: ease of use, optimized operating flows, ease of training, modularity, compactness, reduced size, portability, lightness of weight, ergonomic design, used-friendliness, enhanced practically and low cost.

The present patent of invention relates to a reader device for biological samples used in the field of remote laboratory tests (TLR), for clinical diagnostic purposes, based on an optimized design constituted by a cowling (C) with inlet port (OE) and with switch (I); by a holding support (SS) containing a mirror (ES), two batteries (BT), two reading illumination arrays (BIL), operational status illumination arrays (BIS) and an elevator support (SE); by an elevator (EL); by an electronics board (PE) with energy loading circuit (PE-1), with supply circuit (PE-2), with processor (PE-3), with Bluetooth® device (PE-4) and with position sensor (PE-5); and by a base (BA) with software that reads various types of biological samples, the present invention providing the advantages of: ease of use, optimized operating flows, ease of training, modularity, compactness, reduced size, portability, lightness of weight, ergonomic design, used-friendliness, enhanced practically and low cost.

An optical system includes an optical element and an optical filter with a first set of channels and a second set of channels respectively associated with a first region and a second region of the optical filter. The optical element causes first light beams and second light beams associated with a subject to respectively fall incident on the first region within a first incidence angle range and on the second region within a second incidence angle range. A first channel, of the first set of channels, passes, based on the first incidence angle range, a set of the first light beams that are associated with a first subrange of a particular wavelength range. A second channel, of the second set of channels, passes, based on the second incidence angle range, a set of the second light beams that are associated with a second subrange of the particular wavelength range.

A system for monitoring soil composition within a field may have a ground-engaging tool configured to engage soil within a field as an implement moves across the field. The system may further have a sensor configured to generate data indicative of a soil composition within the field, where the sensor is movable relative to the ground-engaging tool while the implement moves across the field such that the sensor generates data indicative of the soil composition at different depths within the field. Additionally, the system may have a controller communicatively coupled to the sensor, with the controller being configured to determine the soil composition at the different depths within the field based at least in part on the data received from the sensor.

A handheld LIBS device and method includes a laser assembly producing two pulsed single spatial mode output beams and a focusing optic which combines the two pulsed single spatial mode output beams at a focal point at a sample. The laser assembly includes a laser assembly housing with an output coupler window for the two pulsed single spatial mode output beams, a gain medium in the laser assembly housing between the output coupler window and an adjustable prism mount in the laser assembly housing holding a prism configured to establish two light paths through the gain medium, a source in the laser assembly housing providing pump energy to the gain medium, and a Q-switch positioned between the prism and the gain medium.

Provided herein are systems, devices and methods for performing multianalyte detection in a biological sample, such as a human blood sample. Multiwell plates useful for performing multianalyte detection are also provided. The systems, devices and methods provided herein relate to the field of direct-to-consumer diagnostics (DTC diagnostics) and are useful, e.g., for facilitating consumer access to consumer healthcare and consumer wellness information. Other uses of the systems, devices and methods provided herein relate to the fields of medical research and drug discovery.

A multiband IR adjunct (MIRA) sensor to spectroscopically determine the content and the concentration of chemical composition of a targeted object, includes a sensor housing, a first front optics in a first optical channel, a second front optics in the first optical channel, an acousto-optic tunable filter (AOTF), a photo detector (PD), a set of back optics in the first optical channel that focuses polarized narrow-band light beams received from the AOTF device onto the PD, the PD converting the polarized narrow-band light beams into an electrical signal, and a data acquisition unit signal-connected to the PD, the data acquisition unit collecting the electrical signals. Multiple optical channels can be provided within the housing to analyze UV/VIS/near infrared (NIR), short-wavelength infrared (SWIR), mid-wavelength infrared (MWIR), and LWIR wavelength ranges respectively.

A device may include a sensor window. The sensor window may include a substrate. The sensor window may include a set of layers disposed onto the substrate. The set of layers may include a first subset of layers of a first refractive index and a second set of layers of a second refractive index different from the first refractive index. The set of layers may be associated with a threshold transmissivity in a sensing spectral range, and may be configured to a particular color in a visible spectral range and associated with a threshold opacity in the visible spectral range. The device may include a spectral sensor device aligned to the sensor window and including at least one sensor element to receive light in the sensing spectral range and provide a plurality of sensing functionalities based on at least one measurement of the light in the sensing spectral range.

A device may include a sensor window. The sensor window may include a substrate. The sensor window may include a set of layers disposed onto the substrate. The set of layers may include a first subset of layers of a first refractive index and a second set of layers of a second refractive index different from the first refractive index. The set of layers may be associated with a threshold transmissivity in a sensing spectral range, and may be configured to a particular color in a visible spectral range and associated with a threshold opacity in the visible spectral range. The device may include a spectral sensor device aligned to the sensor window and including at least one sensor element to receive light in the sensing spectral range and provide a plurality of sensing functionalities based on at least one measurement of the light in the sensing spectral range.

The present invention pertains to an enzymatic measurement method using an antibody-enzyme complex or a nucleic acid probe measurement method using an enzyme-labeled nucleic acid probe, in both of which the quantification of a product of a reaction by an enzyme in the antibody-enzyme complex or the enzyme-labeled nucleic acid probe is performed by generating thio-NAD(P)H by an enzymatic cycling reaction using NAD(P)H, thio-NAD(P), and a dehydrogenase (DH), and measuring the amount of the generated thio-NAD(P)H or measuring a change in color caused by the generated thio-NAD(P)H. An enzymatic reaction system in which NAD(P) generated from NAD(P)H by the enzymatic cycling reaction is selectively reduced, is caused to coexist with the enzymatic cycling reaction. The present invention also pertains to a kit for enzyme immunoassay, and a kit for nucleic acid probe measurement. In the enzymatic cycling reaction, the detection sensitivity is increased by increasing the amount of thio-NAD(P)H generated per unit time with respect to a predetermined amount of a substrate (reduced), and combining the same with an enzyme immunoassay, etc., enables quantification, etc., of a protein or nucleic acid with high sensitivity.