Patent classifications
G01N2021/755
Systems and methods for detection of chemtiluminescent reactions
Methods, devices and kit for analyzing a sample comprising 1,5-anhydroglucitol and a first analyte via one or more chemiluminescent reactions. Certain embodiments include measuring a first light response resulting from a first chemiluminescent reaction and measuring a second light response resulting from a second chemiluminescent reaction. Certain embodiments also include comparing the first light response to the second light response to determine a ratio of 1,5-anhydroglucitol and the first analyte.
ANALYZER AND ANALYSIS METHOD
Provided are an analyzer that analyzes a specimen with high accuracy and an analysis method for analyzing a specimen with high accuracy. The analyzer according to the present disclosure include a first reaction vessel which contains a reagent, a second reaction vessel which contains a specimen and the reagent, a detector which detects optical characteristics of the first reaction vessel and optical characteristics of the second reaction vessel, and a controller which analyzes components of the specimen in the second reaction vessel using the optical characteristics of the first reaction vessel as a baseline.
System and method for acquisition and processing of multiplexed fluorescence in-situ hybridization images
In acquisition of spatial transcriptomic information, a plurality of images representing a common field of view of a sample are obtained and registered. Each pixel of the registered images is decoded by identifying a code word from a plurality of code words in a code book that provides a best match to data values in the plurality of registered images for the pixel. For each code word identified as a best match and each pixel, whether a bit ratio for an image word for the pixel meets a threshold for the code word is determined. The image word is formed from the data values in the plurality of registered images for the pixel. For at least one pixel that is determined to meet the threshold, a gene associated with the code word is determined. Pixels for which the bit ratio does not meet the threshold are screened.
System for acquisition and processing of multiplexed fluorescence in-situ hybridization images
In a fluorescent in-situ hybridization imaging system performs, as nested loops, the following: (1) a valve sequentially couples a flow cell to a plurality of different reagent sources to expose the sample to a plurality of different reagents, (2) for each reagent of the plurality of different reagents, a motor sequentially positions the fluorescence microscope relative to sample at a plurality of different fields of view, (3) for each field of view of the plurality of different fields of view, a variable frequency excitation light source sequentially emits a plurality of different wavelengths, (4) for each wavelength of the plurality of different wavelengths, an actuator sequentially positions the fluorescence microscope relative to sample at a plurality of different vertical heights, and (5) for each vertical height of the plurality of different vertical heights, an image is obtained.
Method for testing and correcting phase separation in ethanol based fuels
A process, or method, for testing ethanol-based fuel for phase separation and free-standing water, and then correcting the phase separation within the ethanol-based fuel. A method of introducing a desired amount of a chemical into suspension based on an amount of free-standing water that is within the ethanol-based fuel in order to treat and remove any and all amount of free-standing water that is remaining within the suspension.
SYSTEMS AND METHODS FOR DETECTION OF CHEMILUMINESCENT REACTIONS
Methods, devices and kit for analyzing a sample comprising 1,5-anhydroglucitol and a first analyte via one or more chemiluminescent reactions. Certain embodiments include measuring a first light response resulting from a first chemiluminescent reaction and measuring a second light response resulting from a second chemiluminescent reaction. Certain embodiments also include comparing the first light response to the second light response to determine a ratio of 1,5-anhydroglucitol and the first analyte.
Self-indicating colorimetric response materials for removal and sensing of toxic chemicals and narcotics
Processes, compositions, and sensors for sensing a variety of toxic chemicals based on colorimetric changes. Exemplary process for sensing a toxic chemical includes contacting a toxic chemical, or byproduct thereof, with a sorbent that includes a porous metal hydroxide or a porous mixed-metal oxide/hydroxide and a transition metal reactant suitable to react with a toxic chemical or byproduct thereof. The sorbent is contacted with the toxic chemical or byproduct thereof for a sampling time. A difference between a post-exposure colorimetric state of the sorbent and a pre-exposure colorimetric state of the sorbent is determined to thereby detect exposure to, or the presence of, the toxic chemical or byproduct thereof.
Self-indicating colorimetric response materials for removal and sensing of toxic chemicals and narcotics
Processes, compositions, and sensors for sensing a variety of toxic chemicals based on colorimetric changes. Exemplary process for sensing a toxic chemical includes contacting a toxic chemical, or byproduct thereof, with a sorbent that includes a porous metal hydroxide or a porous mixed-metal oxide/hydroxide and a transition metal reactant suitable to react with a toxic chemical or byproduct thereof. The sorbent is contacted with the toxic chemical or byproduct thereof for a sampling time. A difference between a post-exposure colorimetric state of the sorbent and a pre-exposure colorimetric state of the sorbent is determined to thereby detect exposure to, or the presence of, the toxic chemical or byproduct thereof.
In vitro method for sun protection factor determination
The invention provides an in vitro method for the determination of sun protection factor (SPF), in order to gain reproducibility and accuracy and replace the use of tests on living beings. Natural substrates of the human skin, like hyaluronic acid are tested in the form of solutions or in the form of a solid film in a modified spectrophotometer, at concentrations below 1% w/v. Once calibrated, the method is used to corroborate the protection factor offered by commercial sunscreens.
METHOD FOR INSPECTING REFRIGERANT PIPE AND REFRIGERANT PIPE
Provided are a method for inspecting a refrigerant pipe, the method being able to quickly determine durability, and a refrigerant pipe confirmed to be highly durable. The method is a method for inspecting a refrigerant pipe containing copper or a copper alloy. In the method, the refrigerant pipe is exposed to an aqueous alkaline solution and inspected based on a color change of the refrigerant pipe due to exposure of the refrigerant pipe to the aqueous alkaline solution.