A machine for automatic in vitro detection of analytes, the machine being of the type including an optical reader device capable of detecting the optical response of the reaction solution to electromagnetic stimulation using a photoelectric receiver that is carried by a movable carriage of the machine and that moves under automatic control in order to bring the photoelectric receiver into various positions, each corresponding to various respective analysis zones. The photoelectric receiver forms part of a spectrometer capable of delivering a chromatic spectral decomposition of the optical response. Also provided are methods of automatic in vitro detection and/or quantification of analytes. In one method, a chromatic spectral decomposition of the optical response is acquired and two distinct optical agents are detected separately using the spectral decomposition.

Processes, compositions, and sensors for sensing a variety of toxic chemicals based on colorimetric changes. Exemplary process for sensing a toxic chemical includes contacting a toxic chemical, or byproduct thereof, with a sorbent that includes a porous metal hydroxide or a porous mixed-metal oxide/hydroxide and a transition metal reactant suitable to react with a toxic chemical or byproduct thereof. The sorbent is contacted with the toxic chemical or byproduct thereof for a sampling time. A difference between a post-exposure colorimetric state of the sorbent and a pre-exposure colorimetric state of the sorbent is determined to thereby detect exposure to, or the presence of, the toxic chemical or byproduct thereof.

Methods are provided for the automated detection of assay-positive assay areas in a microfluidic device. When assays are performed in a microfluidic device, the configuration of the microfluidic circuit and its constituent circuit elements can determine where the reagents/analytes used in the assay can be located within the microfluidic circuit. Methods are provided for automatic identification of the size and shape of the assay areas based on a number of parameters which may include type of assay involved, shape and dimensions of microfluidic circuit elements, velocity and physical characteristics of the fluidic medium within the microfluidic circuit, physical/chemical properties of the analytes/reagents, and/or the number of cells being assayed.

In a starch concentration measurement, a liquid sample is conducted from a liquid sample such as pulp suspension or filtrate of a paper, board or tissue process. An iodine solution is added to the sample, and a light absorbance or transmittance of the sample is measured at a target wavelength. The measured absorbance or transmittance of the sample is then converted into the starch concentration of the sample.

A blood analysis method comprising, acquiring optical information which changes over time from a mixed liquid of a blood sample and a reagent for coagulation time measurement after mixing the blood sample and the reagent, and acquiring information related to a coagulation time and information related to a number of platelets in the blood sample based on the acquired optical information.

Disclosed are a cell evaluation device, a cell evaluation method, and a non-transitory computer readable recording medium recorded with a cell evaluation program capable of evaluating individual cells in a cell image obtained by imaging a cell group with high accuracy. The cell evaluation device includes an image acquisition unit 30 that acquires a cell image obtained by imaging a cell group; a cell evaluation unit 32 that specifies an evaluation target cell and peripheral cells around the evaluation target cell in the cell group and evaluates the evaluation target cell based on evaluation results of the peripheral cells.

A method for determining whether a testing specimen is supplied to a testing system, which comprises: a reaction tank in which the testing specimen reacts; a light source for emitting testing light into the reaction tank from one side of the reaction tank; and a photoelectric sensor that is placed on the side of the reaction tank opposite to the light source for receiving the testing light traveled through the reaction tank and that converts the received testing light into an electrical signal. Determining. The amount of the testing specimen to be added into the reaction tank is set so that the level of the testing specimen is above the light path of the testing light while the reaction tank is cleaned. Whether the testing specimen is supplied is determined based on the presence of change of the electrical signal output from the photoelectric sensor. determined

The present disclosure relates to a biological detection chip and a detecting method thereof. The biological detection chip includes a light guiding substrate having a top surface, a bottom surface opposite to the top surface, and a side surface between the top surface and the bottom surface, and a biosensitive membrane on the top surface of the light guiding substrate.

A method of monitoring water-soluble treatment chemicals in a fluid that is immiscible with water and which may or may not contain some aqueous fluid, the method using at least one reagent that produces an optically detectable product, the detection step can take place without separation of the aqueous phase containing the treatment chemicals from the fluid immiscible with water.

A method includes receiving a sample. The method also includes applying a denaturing agent to a first portion of the sample, and detecting, in response to the application of the denaturing agent, a first measure from the first portion of the sample. The method also includes modifying the temperature of a second portion of the sample and detecting, in response to the modifying the temperature of the second portion of the sample, a second measure from the second portion of the sample. The method also includes computing thermodynamic information for the sample based on the indication of the first measure, and computing kinetic information for the sample based on the indication of the second measure. The method also includes computing, based on the thermodynamic information and the kinetic information, an indication of temporal stability of the protein component of the sample.