G01N21/8483

ADJUSTMENT METHOD FOR ADJUSTING A SETUP FOR AN ANALYTICAL METHOD
20220317050 · 2022-10-06 ·

This disclosure refers to an adjustment method for adjusting a setup for an analytical method of determining a concentration of an analyte in a bodily fluid based on a color formation reaction in an optical test strip mobile device for performing analytical measurements. This disclosure further relates to a mobile device configured for performing the adjustment method, a computer program and a computer-readable storage medium for performing the adjustment method and a kit comprising a test strip or a dummy test strip and at least one of the mobile device, the computer program and the computer-readable storage medium. The method, device, computer program, storage media and kit specifically may be used in medical diagnostics, for example, qualitatively or quantitatively detect analytes in body fluids, such as for detecting glucose in blood and/or interstitial fluid. Other fields of application of this disclosure, however, are feasible.

DETECTION SYSTEM AND A PORTABLE DETECTION DEVICE
20230103404 · 2023-04-06 ·

A detection system and a portable detection device for detecting an object of interest in a lateral flow immunoassay strip. The lateral flow immunoassay strip has a detection carrier and a reporter, the detection carrier has a control zone and a test zone. The detection system has a laser light source, a scanning and spatial modulation module, a signal acquisition assembly, and a processing device. The laser light source provides a laser light. The scanning and spatial modulation module receives the laser light, and then provides a scanning and spatially modulating laser beam for irradiating a lateral flow immunoassay strip to generate a detecting signal. The signal acquisition assembly receives the detecting signal. The processing device electronic connects to the signal acquisition assembly and receives the detecting signal from the signal acquisition assembly.

Time-resolved fluorescence immunochromatographic test paper card for testing clothianidin

A time-resolved fluorescence immunochromatographic test paper card for testing clothianidin. A binding pad includes a detection microsphere and a quality control microsphere thereon, wherein the detection microsphere is a fluorescent microsphere coated with a clothianidin monoclonal antibody on the surface thereof, the quality control microsphere is a fluorescent microsphere coated with a rabbit anti-tag protein on the surface thereof. An NC film is provided with a detection line and a control line. The lengths of the detection line and the control line are the same as the width of the NC film. A first clamping part is arranged at one end of the sample pad. A second clamping part and a third clamping part are respectively arranged at two ends of the binding pad. A fourth clamping part is arranged at one end of the NC film, the other end of the NC film is joined with an absorption pad.

MULTIPLE STRIP READER
20230152238 · 2023-05-18 ·

An improved test-strip reader with multi-strip loading carriage capable of loading a plurality of test strips at once and automatically identifying them, referencing their positions, cataloguing/indexing them, calibrating them, imaging them, and correcting and analyzing them. The loading carriage has a plurality of imaging beds to seat and position individual strips, and a clamping mechanism to affix them therein. When the user places the test strips in the carriage and initiates insertion into the enclosure, a latch maintains position, and the remainder of the imaging and analysis process is completed automatically with an internal imaging assembly. The apparatus makes it possible to measure various reagents at once including Free Chlorine (FC), total alkalinity (TA), cyanuric acid (CYA), total chlorine (TC), bromine (Br), and pH as typical of a pool or spa. It further maximizes ease and efficiency of use and minimizes risk of user error.

OPTICAL MEASUREMENT DEVICE AND OPTICAL MEASUREMENT METHOD

An optical measurement device 1 includes: a measurement unit; and a determination unit, wherein the determination unit calculates a difference value between the initial measurement value and the latter measurement value when the measurement value exceeds the first threshold value after the sample is held by the lateral flow test strip, determines that the sample is positive when the difference value exceeds a second threshold value set in advance, and determines that the sample is negative when the difference value is the second threshold value or less.

OPTICAL DETECTOR

An optical detector (1) on an application specific integrated circuit (ASIC) comprises at least one photodiode (5) for receiving incident light and configured to provide at least one diode signal, a modulator (2) configured to provide an AC drive signal and to provide a reference signal associated with the AC drive signal; and a lock-in amplifier (6) configured to receive said at least one diode signal from said at least one photodiode (5) and to receive the reference signal from the modulator (2), and to determine at least one of a phase and an amplitude of said at least one diode signal using the reference signal.

METHODS FOR DETERMINING THE CONCENTRATION OF AN ANALYTE IN THE PLASMA FRACTION OF A SAMPLE OF WHOLE BLOOD

The precision of a lateral flow assay for determining the concentration of an analyte in the plasma fraction of a sample of whole blood can be significantly improved by applying an integrated step for determining the hematocrit of the optionally diluted sample, and taking both hematocrit and dilution factor into account when calculating the concentration of the analyte. This is made possible inter alia by using a predetermined wavelength when taking an image of the sample after application to a substrate in the lateral flow assay device, and wherein said wavelength is selected based on the dilution factor used. This hematocrit measurement is advantageously integrated in lateral flow assay methods and devices for the measurement of an analyte in plasma and contributes significantly to an improved precision of such assays.

Assay reader, device and method of measuring HCG

Disclosed is a method for determining a quantitative estimate of the length of time since conception in a female mammalian subject, the method comprising: a) providing a liquid sample suspected of containing hCG; b) measuring, by means of an assay or assay device, an analyte measurement signal, whose value is dependent upon the level of hCG; c) comparing the measured signal value to an analyte threshold, wherein said analyte threshold corresponds to a time since conception; d) providing an quantitative estimate of the length of time since conception based upon the comparison in step (c).

METHOD AND APPARATUS FOR ELECTRONIC DETECTION AND DETERMINATION

Method and apparatus for electronic detection and determination includes detecting a signal T0 in a detection zone and a signal R0 in a reference zone before a sample is added; adding a sample and detecting the signals in each of the detection zone and the reference zone at an interval of a second preset period; calculating a judgement value based on 2k immediately previous signals in each of the detection zone and the reference zone, the signal T0 in the detection zone before the sample is added, and the signal R0 in the reference zone before the sample is added, each time when k successive signals are detected in each of the detection zone and the reference zone; and determining a judgement result based on m successive judgement values and a preset result threshold corresponding to a current detection time.

DEVICE FOR DETECTING AND ANALYTE IN SAMPLE

The present invention relates to a device for detecting an analyte in a sample, of which the sensitivity is improved by changing the structure. The device for detecting analyte in a sample of the present invention has the effect of improving measurement sensitivity and accuracy by arranging a light source and a photosensor to correspond to an inspection area and a control area, forming holes at positions corresponding to respective light source units, the photosensor, the inspection area, and a calibration area, and adding a stick housing having stick housing partitions formed around the holes.