G01N25/04

Method and apparatus for generating thermal melting curves in a microfluidic device

The present invention provides novel methods and devices that employ microfluidic technology to generate molecular melt curves. In particular, the devices and methods in accordance with the invention are useful in providing for the analysis of PCR amplification products.

Viscometer and methods for using the same
11162885 · 2021-11-02 · ·

A viscometer includes a viscosity sensor with a liquid flow channel and at least two pressure sensors positioned along the liquid flow channel and configured to measure a pressure drop of a liquid flowing through the liquid flow channel, and a dispensing mechanism configured to cause dispensing of a liquid from the syringe to the viscosity sensor at a known flow rate. The dispensing mechanism and the viscosity sensor are configured to couple with a syringe configured to contain a liquid. The viscometer further includes an electronic controller configured to control operations of the dispensing mechanism and receive and process data from the viscosity sensor. The viscometer includes a sample loading interface, included in the syringe, through which the viscometer is configured to receive the liquid. The sample loading interface includes a selection valve coupled with, and located between, the viscosity sensor and the syringe.

Viscometer and methods for using the same
11162885 · 2021-11-02 · ·

A viscometer includes a viscosity sensor with a liquid flow channel and at least two pressure sensors positioned along the liquid flow channel and configured to measure a pressure drop of a liquid flowing through the liquid flow channel, and a dispensing mechanism configured to cause dispensing of a liquid from the syringe to the viscosity sensor at a known flow rate. The dispensing mechanism and the viscosity sensor are configured to couple with a syringe configured to contain a liquid. The viscometer further includes an electronic controller configured to control operations of the dispensing mechanism and receive and process data from the viscosity sensor. The viscometer includes a sample loading interface, included in the syringe, through which the viscometer is configured to receive the liquid. The sample loading interface includes a selection valve coupled with, and located between, the viscosity sensor and the syringe.

Casting solidification analysis method, casting method, and electronic program
11745258 · 2023-09-05 ·

A casting solidification analysis method, which can analyze positions of shrinkage cavities more accurately than in the past, a casting method using the above method, and an electronic program are provided. A following casting solidification analysis method is provided. An amount of expansion/shrinkage for each solidification step length separated by inflection points in a cooling curve is determined, by setting a solid phase ratio at a completion of pouring to 0, setting a solid phase ratio at an end of solidification to 1.0, and determining the expansion/shrinkage amount for the each solidification step length by proportionally distributing the each solidification step length to the total solid phase ratio length.

Method for Testing Frost Susceptibility of Soils and Associated Apparatus
20230366868 · 2023-11-16 ·

The present disclosure provides a method for testing frost susceptibility of soils and an associated apparatus, and relates to the field of testing technology. The method includes: taking a part of a soil sample to be tested as test soil sample and freezing the test soil sample; taking a soil sample of outer layer from the test soil sample after the completion of freezing and measuring the moisture ratio of the soil sample of outer layer; and determining the frost susceptibility of the soil sample to be tested based on an initial moisture ratio and the moisture ratio of the soil sample of outer layer or based on the moisture ratio of the soil sample of outer layer and the moisture ratio of a soil sample of inner layer from the test soil sample after the completion of freezing. frost susceptibility

Method for Testing Frost Susceptibility of Soils and Associated Apparatus
20230366868 · 2023-11-16 ·

The present disclosure provides a method for testing frost susceptibility of soils and an associated apparatus, and relates to the field of testing technology. The method includes: taking a part of a soil sample to be tested as test soil sample and freezing the test soil sample; taking a soil sample of outer layer from the test soil sample after the completion of freezing and measuring the moisture ratio of the soil sample of outer layer; and determining the frost susceptibility of the soil sample to be tested based on an initial moisture ratio and the moisture ratio of the soil sample of outer layer or based on the moisture ratio of the soil sample of outer layer and the moisture ratio of a soil sample of inner layer from the test soil sample after the completion of freezing. frost susceptibility

SMALL VOLUME SYSTEM AND METHODS OF EVALUATING THE STABILITY OF BIOPHARMACEUTICAL COMPOSITIONS

An analysis container includes an outer tube and a plurality of inner tubes. The outer tube defines a buffer volume that is configured to receive a buffer material. The plurality of inner tubes is disposed within the buffer volume. Each inner tube has an inner diameter equal to or less than 6 mm and is configured to receive a biopharmaceutical composition therein. The outer tube is configured such that the buffer material and the biopharmaceutical composition are axially frozen.

SMALL VOLUME SYSTEM AND METHODS OF EVALUATING THE STABILITY OF BIOPHARMACEUTICAL COMPOSITIONS

An analysis container includes an outer tube and a plurality of inner tubes. The outer tube defines a buffer volume that is configured to receive a buffer material. The plurality of inner tubes is disposed within the buffer volume. Each inner tube has an inner diameter equal to or less than 6 mm and is configured to receive a biopharmaceutical composition therein. The outer tube is configured such that the buffer material and the biopharmaceutical composition are axially frozen.

DETECTION DEVICE, DETECTION METHOD, AND RECORDING MEDIUM
20220283104 · 2022-09-08 · ·

The disclosure provides a detection device, a detection method, and a recording medium. The detection device includes: an acquisition unit for acquiring the temperature of a solder in a solder bath; a measurement unit for measuring the melting point of the solder from a temporal change in temperature in at least one of a temperature increasing process and a temperature decreasing process; and a detection unit for detecting variation in the copper concentration of the solder on the basis of variation in the melting point.

DETECTION DEVICE, DETECTION METHOD, AND RECORDING MEDIUM
20220283104 · 2022-09-08 · ·

The disclosure provides a detection device, a detection method, and a recording medium. The detection device includes: an acquisition unit for acquiring the temperature of a solder in a solder bath; a measurement unit for measuring the melting point of the solder from a temporal change in temperature in at least one of a temperature increasing process and a temperature decreasing process; and a detection unit for detecting variation in the copper concentration of the solder on the basis of variation in the melting point.