A device for analysis of cells comprises: an active sensor area (104) presenting a surface for cell growth; a microelectrode array (102) comprising a plurality of pixels (110) in the active sensor area (104), wherein each pixel (110) comprises at least one electrode (120) at the surface, wherein each pixel (110) is configured to control the configuration of the pixel circuitry and set a measurement modality of the pixel; recording circuitry having a plurality of recording channels (130), wherein each pixel (110) is connected to a recording channel (130), wherein each recording channel (130) comprises a reconfigurable component (131), which is selectively controlled between being set to a first mode, in which the reconfigurable component (131) is configured to amplify a received pixel signal, and being set to a second mode, in which the reconfigurable component (131) is configured to selectively pass a frequency band of the received pixel signal.

An apparatus and method to detect disease-specific antigens assists in disease diagnosis. Point-of-care (POC) micro biochip incorporates at least one hydrophilic microchannel for controlled and self-driven flow of body fluid. Metallic nano-interdigitated electrodes disposed within the channels give enhanced sensitivity detection. Microchannel controls flow and amplifies a capillary effect. Electrodes are fabricated on microchannel surface to detect biomolecular interactions. When a sample flows through microchannel, disease-specific antigens from the sample form antigen-antibody complex with antibodies immobilized on electrodes. Antigen-antibody interaction is detected via an electrical change in the biochip's nano circuit. Each electrode may include a different antibody to detect different antigens. Capacitance during antigen-antibody interaction without microfluidic flow is higher than with microfluidic flow due to immobilized antibodies instability on sensing surface caused by shear stress. POC biochip provides nano level detection of many disease-specific antigens of any type based on micro volume or single drop sized sample.

A method for determining a value indicative of the permittivity of a cell population in the context of impedance spectroscopy comprises the following steps: generating an excitation current through the cell population, which oscillates with an excitation frequency; measuring a voltage in the cell population between a first measuring electrode (12) and a second measuring electrode (14); sampling the excitation current, wherein first sampled values for the excitation current are generated; sampling the voltage between the first measuring electrode (12) and the second measuring electrode (14), wherein second sampled values for the voltage between the first measuring electrode and the second measuring electrode are generated; and determining the value indicative of the permittivity of the cell population on the basis of the first sampled values and the second sampled values.

The invention discloses an impedance spectrum in-situ measuring device for the dielectric constant of solid materials at high temperature and high pressure conditions. The device comprises a cube-shaped pyrophyllite, a cylindrical opening penetrates between one end face of the pyrophyllite and the other end face opposite to the end face; a heater formed by sleeving annular stainless steel sheets is arranged in the opening; a first plate-shaped platinum electrode and a second plate-shaped platinum electrode are arranged in the cavity of the innermost ring-shaped stainless steel sheet. The first plate-shaped platinum electrode is electrically connected with one end of the Solartron 1260 Impedance/Gainphase Analyzer through a first lead, and the second plate-shaped platinum electrode is electrically connected with the other end of the Solartron 1260 Impedance/Gainphase Analyzer through a second lead. Several layers of machinable alumina fillers are filled between the sample of the solid material to be measured and the innermost annular stainless steel sheet. The device also comprises a first cylindrical plug and a second cylindrical plug. The device can be considered as a useful tool in study on the properties of the dielectric constant of the solid material to be measured at high temperature and high pressure conditions.

A sensing device includes at least one particle sensor that responds to sensed subatomic particles. At least one drive-sense circuit is coupled to the particle sensor, wherein the at least one drive-sense circuit includes: a first conversion circuit configured to convert a receive signal component of a sensor signal corresponding to the at least one particle sensor into the sensed signal, wherein the sensed signal indicates a change in an electrical characteristic associated with the at least one particle sensor; and a second conversion circuit configured to generate, based on the sensed signal, a drive signal component of the sensor signal corresponding to the at least one particle sensor.

Disclosed is a wireless monitoring system for a coal-gangue mixing ratio based on a non-Hermite technology, including a signal generation monitoring device, an excitation coil, a receiving coil and a parallel plate capacitor. The signal generation monitoring device is connected with the excitation coil; the receiving coil is connected with the parallel plate capacitor to form an LC resonance system; the receiving coil is placed in parallel with the excitation coil, and the axis of the receiving coil and the axis of the excitation coil are on a same horizontal line; the signal generation monitoring device is used to generate a pulse current and collect reflected signals; the excitation coil excites an initial magnetic field based on the generated pulse current, and the LC resonance circuit performs an electromagnetic field induction to generate an induced magnetic field, and feeds back the reflected signals to the signal generation monitoring device.

Described herein is a system for detecting microbial contamination in a liquid storage container, such as a fuel storage tank or a water storage tank. The system can include one or more impedance sensor arrays positioned within the fuel storage container and a computer system coupled to the impedance sensor arrays. The computer system configured to detect microbial growth within the fuel storage container based on changes in impedance across the impedance sensor array. The system can be embodied as a standalone system or can be incorporated into the fuel tank's existing systems.

The present invention discloses a measuring method for a semiconductor gas sensor based on alternating-current impedance. The method includes the steps: connecting the semiconductor gas sensor to a capacitor in parallel, connecting an alternating-current impedance measuring device to the semiconductor gas sensor and the capacitor, combining measuring parameters under measuring frequencies within a first preset range and parallel capacitance values within a second preset range, and measuring a gas with a known concentration according to each of nine features under each combination; traversing all parameter combinations and all the nine features to obtain a plurality of feature values corresponding to the same gas concentration under each feature; and selecting measuring frequencies within a third range, parallel capacitance values within a fourth range and a certain or several of the corresponding features as measuring parameters finally selected for measuring an unknown gas concentration.

A high-gain and low-noise negative feedback control (“feedback control”) system can detect charge transfer in quantum systems at room temperatures. The feedback control system can attenuate dissipative coupling between a quantum system and its thermodynamic environment. The feedback control system can be integrated with standard commercial voltage-impedance measurement system, for example, a potentiostat. In one aspect, the feedback control system includes a plurality of electrodes that are configured to electrically couple to a sample, and a feedback mechanism coupled to a first electrode of the plurality of electrodes. The feedback mechanism is configured to detect a potential associated with the sample via the first electrode. The feedback mechanism provides a feedback signal to the sample via a second electrode of the plurality of electrodes, the feedback signal is configured to provide excitation control of the sample at a third electrode of the plurality of electrode.

Certain disclosed methods include: transmitting an excitation signal into the MUT and transmitting a reference signal to a set of magnitude and phase (M/P) detectors; receiving the response signal; separately comparing a magnitude and phase for each of the excitation signal and the reference signal with corresponding detection ranges for a first one of the M/P detectors; separately comparing a magnitude and phase for each of the response signal and the reference signal with corresponding detection ranges for a second one of the M/P detectors; iteratively adjusting the excitation signal until the response signal has both a magnitude and a phase within the corresponding detection ranges for the second M/P detector; and iteratively adjusting the reference signal until the reference signal has both a magnitude and a phase within the corresponding detection ranges for the first and the second M/P detectors.