The present disclosure provides a trace detection device. The trace detection device includes: a box body comprising a main body frame and a top plate, the top plate and the main body frame forming a fully enclosed cavity; an ion migration tube assembly in the cavity and on a first side of the cavity; and a preamplifier and high voltage circuit board in the cavity and on a second side of the cavity, the second side being opposite to the first side.

The present invention is directed to a method and device to desorb an analyte using heat to allow desorption of the analyte molecules, where the desorbed analyte molecules are ionized with ambient temperature ionizing species. In various embodiments of the invention a current is passed through a mesh upon which the analyte molecules are present. The current heats the mesh and results in desorption of the analyte molecules which then interact with gas phase metastable neutral molecules or atoms to form analyte ions characteristic of the analyte molecules.

The present invention is directed to a method and device to desorb an analyte using heat to allow desorption of the analyte molecules, where the desorbed analyte molecules are ionized with ambient temperature ionizing species. In various embodiments of the invention a current is passed through a mesh upon which the analyte molecules are present. The current heats the mesh and results in desorption of the analyte molecules which then interact with gas phase metastable neutral molecules or atoms to form analyte ions characteristic of the analyte molecules.

An apparatus for performing ambient ionization mass and/or ion mobility spectrometry is disclosed. The apparatus comprises a substantially cylindrical, tubular, rod-shaped, coil-shaped, helical or spiral-shaped collision assembly; and a first device arranged and adapted to direct analyte, smoke, fumes, liquid, gas, surgical smoke, aerosol or vapor onto said collision assembly.

An apparatus for performing ambient ionization mass and/or ion mobility spectrometry is disclosed. The apparatus comprises a substantially cylindrical, tubular, rod-shaped, coil-shaped, helical or spiral-shaped collision assembly; and a first device arranged and adapted to direct analyte, smoke, fumes, liquid, gas, surgical smoke, aerosol or vapor onto said collision assembly.

An atom probe directs two or more pulsed laser beams onto a specimen, with each laser beam being on a different side of the specimen, and with each laser beam supplying pulses at a time different from the other laser beams. The laser beams are preferably generated by splitting a single beam provided by a laser source. The laser beams are preferably successively aligned incident with the specimen by one or more beam steering mirrors, which may also scan each laser beam over the specimen to achieve a desired degree of specimen ionization.

The present invention relates to the field of mass and/or ion mobility spectrometers. Provided is an ionization device and a mass spectrometer and an ion mobility spectrometer having same. Further provided is an ionization method. A sampling probe of the ionization device of the present invention is able to actively and rapidly collect samples, while a sampling device and a thermal desorption device are combined into one, simplifying and compacting the sampling device. An ionization part is provided downstream of the sampling and desorption part, ensuring that the sampling probe will not interfere with a flow field or an electric field between the ionization part and the analysis assembly inlet, thus ensuring repeatability of the device signal and flexibility of analysis.

The present invention includes a first flow path through which a sample gas flows, a first analyzer that is provided in the first flow path to measure total hydrocarbon concentration in the sample gas, a second flow path through which the sample gas flows, a non-methane non-ethane cutter that is provided in the second flow path to remove the hydrocarbon components other than the methane and the ethane in the sample gas, a second analyzer that is provided downstream of the non-methane non-ethane cutter in the second flow path to measure the total methane ethane concentration of the methane and the ethane in the sample gas, and a calculation part that calculates the concentration of the hydrocarbon components other than the methane and the ethane in the sample gas with use of the total hydrocarbon concentration by the first analyzer and the total methane ethane concentration by the second analyzer.

The present invention includes a first flow path through which a sample gas flows, a first analyzer that is provided in the first flow path to measure total hydrocarbon concentration in the sample gas, a second flow path through which the sample gas flows, a non-methane non-ethane cutter that is provided in the second flow path to remove the hydrocarbon components other than the methane and the ethane in the sample gas, a second analyzer that is provided downstream of the non-methane non-ethane cutter in the second flow path to measure the total methane ethane concentration of the methane and the ethane in the sample gas, and a calculation part that calculates the concentration of the hydrocarbon components other than the methane and the ethane in the sample gas with use of the total hydrocarbon concentration by the first analyzer and the total methane ethane concentration by the second analyzer.

A chemical trace detection system includes: a drift tube; a detector disposed within the drift tube; a voltage source to produce an electrical field in the drift tube; an ionizer to establish an ionization region adjacent to the electrical field; and a desorber including a sample holder to hold a sample in or adjacent to the ionization region and a sample heater to desorb particles of the sample held in the sample holder such that the desorbed particles are introduced directly into the ionization region from the sample holder to form ionized particles that are forced toward the detector by the electrical field. A regenerable dryer assembly for supplying dry drift gas to an ion mobility spectrometer is also provided that includes a regenerable desiccant material.