A parallel assembly (2; 11; 51) of chromatography column modules (3a,b,c; 13a,b,c; 53a,b,c, 90a, b) connected in a rigid housing (21; 61), the assembly having one common assembly inlet (15; 55) and one common assembly outlet (17; 57), each column module comprising a bed space (29) filled with chromatography medium and each column module comprises integrated fluid conduits which when the column module is connected with other column modules in the rigid housing are adapted to connect the bed space (29) of the column module with the assembly inlet (15; 55) and the assembly outlet (17; 57), wherein the total length and/or volume of the fluid conduit from the assembly inlet to one bed space together with the length and/or volume of the fluid conduit from the same bed space to the assembly outlet is substantially the same for all bed spaces and modules installed in the parallel assembly.

A device for separating one or more molecules of interest in a liquid specimen including a monolithic body defining a fractionation column. The column includes an inlet opening at a proximal end of the fractionation column; an outlet opening at a distal, opposite end of the fractionation column; a solid phase chamber positioned between the inlet opening and the outlet opening; a specimen introduction area adjacent a proximal end of the solid phase chamber; an analyte exit area adjacent a distal end of the solid phase chamber; an inlet chamber adjacent the inlet opening that tapers into the specimen introduction area; and an outlet chamber that extends from the analyte exit area to the outlet opening. A metered amount of solid phase packed within the solid phase chamber between a first porous frit and a second porous frit of the solid phase chamber.

Provided is a column tube for chromatography that can prevent a peak shape abnormality referred to as a foot in a resulting chromatogram. The object is accomplished by the column tube for chromatography, through which a fluid flows, this column tube including a plurality of polishing traces extending on an inner circumferential surface of the column tube in a flow direction of the fluid.

A first liquid raw material and a second liquid raw material are reacted with each other by a reactor of a reaction device, so that a reaction product is produced. The reaction product is analyzed by an analyzer. In the controller, the reference value is acquired by the reference value acquirer from the chromatogram obtained from the result of the analysis by the analyzer. An upper limit value and a lower limit value with respect to the reference value are set by an allowable range setter. At least one of a residence time of the first liquid raw material, a residence time of the second liquid raw material, a reaction temperature, and a reaction pressure in the reactor is dynamically changed as a control target by a reaction controller such that the reference value falls between the upper limit value and the lower limit value.

A first liquid raw material and a second liquid raw material are reacted with each other by a reactor of a reaction device, so that a reaction product is produced. The reaction product is analyzed by an analyzer. In the controller, the reference value is acquired by the reference value acquirer from the chromatogram obtained from the result of the analysis by the analyzer. An upper limit value and a lower limit value with respect to the reference value are set by an allowable range setter. At least one of a residence time of the first liquid raw material, a residence time of the second liquid raw material, a reaction temperature, and a reaction pressure in the reactor is dynamically changed as a control target by a reaction controller such that the reference value falls between the upper limit value and the lower limit value.

Exemplary embodiments are directed to devices for separating a sample by chromatography, components of the devices, and methods for using the devices, and directed to devices and components for use with immobilized enzymatic reactors. A device includes a wall having a wetted surface exposed to a mobile phase including the sample during chromatographic separation. The wetted surface of the wall includes an alloy material including the following constituents: nickel, and cobalt and/or chromium where the alloy is limited in an amount of titanium to 1 wt %. A component includes a body having a wetted surface exposed to a mobile phase including the sample during chromatographic separation. The wetted surface of the body includes an alloy material including the following constituents: nickel, and cobalt and/or chromium where the alloy is limited in an amount of titanium to 1 wt %.

A portable gas analysis device having a separating column and a detector. The separating column is composed as a multi-capillary unit from parallel individual capillaries and, depending on the length, is bent into a compact shape, preferably even wound into multiple turns. A thermally conductive casing and a thermal stabilizing device are provided for the multi-capillary unit. The thermal stabilizing device comprises a temperature sensor, a heating element and control electronics. The casing protects the sensitive multi-capillary unit from mechanical actions; it acts as a protective space. The temperature-controlled casing also forms a space in which uniform and controlled conditions prevail and which in particular is isolated from the temperature and humidity of the environment, allowing reliable measurements outside a laboratory environment, in the field. This double effect of the casing for the capillaries in conjunction with the compact dimensions forms the true essence of the invention.

Provided herein is a valve manifold comprising (a) an elastomer sheet attached to a plurality of magnetic pistons, wherein the magnetic pistons project from a first side of the elastomer sheet; (b) a foot component comprising a first surface and a plurality of shafts that orthogonally pass through the first surface; and (c) a body component comprising a second surface, a groove that laterally passes along the second surface, and a plurality of reservoir channels that orthogonally pass through the second surface, wherein the elastomer sheet is compressed between the foot component and the body component.

An improved gas chromatography system is presented. The system comprises: an enclosure having an inlet and an outlet, such that the ventilation flow is from the inlet to the outlet; a chamber disposed in the enclosure; a monolithic gas analyzer disposed in the chamber and a temperature control unit disposed in physical contact with the chamber. The monolithic gas analyzer operates to separate and detect molecules from a gas; whereas, the temperature control unit is configured to control temperature inside the chamber.

The invention relates to a method for preparing a monolithic stationary phase in the interior volume of a chromatography column made of thermoplastic polymer. This method comprises the following steps: (i) modifying the inner wall of the chromatography column by implementing the following steps: (a) preparing a polymerizable anchoring composition comprising at least one particular methacrylate monomer, one or more solvents and 2,2-dimethoxy-2-phenylacetophenone, (b) depositing, on the inner wall of the column, the polymerizable anchoring composition prepared in step (a), and (c) polymerizing the polymerizable anchoring composition by irradiation with ultraviolet radiation; (ii) introducing, into the interior volume of the column, a polymerizable monolith synthesis composition comprising first and second particular (meth)acrylate monomers, one or more pore-forming agents and a free-radical polymerization initiator; and (iii) polymerizing the polymerizable monolith synthesis composition. The invention also relates to a method for producing a chromatography column comprising such a monolithic stationary phase and to a chromatographic separation method using such a column.