G01N30/86

Data-processing device for chromatograph

The present invention is a data-processing device used for a chromatograph which continuously performs a series of analyses for components in each sample while sequentially introducing a plurality of samples into a column. The device includes: an input section configured to allow for input of information into a schedule table for a plurality of analyses, the schedule table describing an analysis condition including a combination of the values of a plurality of control parameters, the order of execution of the plurality of analyses, and information for identifying a sample to be subjected to each analysis; a chromatogram creating means configured to receive data sequentially collected during two or more analyses and create a joint chromatogram from the data if the two or more analyses have been continuously performed for the same sample according to the schedule table; and a display means configured to display the joint chromatogram.

Chromatographic data system processing apparatus

A chromatographic data system processing apparatus includes a standard sample time table for prestoring a first retention time and a first allowable width of each peak of specific components of a standard sample, a determination unit for determining whether a number of peaks coincides with a specified number when a peak cannot be identified, an alteration unit for altering the standard sample time table by increasing the first allowable width of a specific component to an altered allowable width, an identification unit for identifying the peaks based on the altered standard sample time table when all peaks fall within a range of the altered allowable width, and a setting unit for acquiring an actually-measured retention time of the peaks, and setting a measurement sample time table based on the actually-measured retention time and a second allowable width when the peaks are identified based on the altered standard sample time table.

State determination of a fluidic system
11567042 · 2023-01-31 · ·

A method for determining a state of a fluidic system can include measuring back pressures in the fluidic system at different times and determining a state of the fluidic system. The determination is based on at least the measured back pressures and on additional status information indicative of at least one status of the fluidic system at at least one of the different times.

State determination of a fluidic system
11567042 · 2023-01-31 · ·

A method for determining a state of a fluidic system can include measuring back pressures in the fluidic system at different times and determining a state of the fluidic system. The determination is based on at least the measured back pressures and on additional status information indicative of at least one status of the fluidic system at at least one of the different times.

CONTROLLING THE PURIFICATION OF A MACROMOLECULE SOLUTION VIA REAL-TIME MULTI-ANGLE LIGHT SCATTERING
20230022034 · 2023-01-26 · ·

The present disclosure describes a computer implemented method, a system, and a computer program product of controlling the purification of a macromolecule solution via real-time multi-angle light scattering.

CHEMICAL PATTERN RECOGNITION METHOD FOR EVALUATING QUALITY OF TRADITIONAL CHINESE MEDICINE BASED ON MEDICINE EFFECT INFORMATION

A chemical pattern recognition method for evaluating the quality of a traditional Chinese medicine based on medicine effect information, comprising: collecting chemical information of a traditional Chinese medicine sample, obtaining medicine effect information reflecting a clinical therapeutic effect thereof, performing spectrum-effect relationship analysis on the chemical information and the medicine effect information, and obtaining an index significantly related to the medicine effect as a feature chemical index; dividing the traditional Chinese medicine sample into a training set and a test set; using a pattern recognition method to extract a feature variable from samples of the training set by taking the feature chemical index as an input variable; building a pattern recognition model using the feature variable; and substituting feature variable values of samples of the test set into the model, and completing chemical pattern recognition evaluation of the quality of the traditional Chinese medicine. According to the method, chemical reference substances are not needed, the chemical pattern recognition model is built on the basis of the feature chemical index reflecting the medicine effect, the one-sidedness and the subjectivity of the existing standards are overcome, and a traditional Chinese medicine quality evaluation system capable of reflecting both the clinical therapeutic effect and overall chemical composition information is finally formed.

Method for identifying and analyzing dissolved organic nitrogen of different sources in wastewater and application of the method
11703495 · 2023-07-18 · ·

A method for identifying and analyzing dissolved organic nitrogen of different sources in wastewater includes extracting DON in wastewater to obtain a DON extract, detecting mass spectrum peaks in the DON extract, pre-processing the spectral data of the wastewater sample; constructing a network relationship of the substance reaction in the wastewater sample; screening the substance reaction relationship of DON; and determining different sources of DON.

Method for measuring glycated hemoglobin and device for measuring glycated hemoglobin
11555807 · 2023-01-17 · ·

A method for measuring a proportion of sA1c (%), which includes, when a peak derived from abnormal hemoglobin D, abnormal hemoglobin S or abnormal hemoglobin C is identified, calculation of the peak area, and measurement of the proportion of sA1c (%) corrected by using the calculation results. Results of measurement are obtained, by cation exchange chromatography, of sA1c (%) with a subject who provided a blood sample containing abnormal hemoglobin D, abnormal hemoglobin S or abnormal hemoglobin C by eliminating influences by such abnormal hemoglobin.

Method for measuring glycated hemoglobin and device for measuring glycated hemoglobin
11555807 · 2023-01-17 · ·

A method for measuring a proportion of sA1c (%), which includes, when a peak derived from abnormal hemoglobin D, abnormal hemoglobin S or abnormal hemoglobin C is identified, calculation of the peak area, and measurement of the proportion of sA1c (%) corrected by using the calculation results. Results of measurement are obtained, by cation exchange chromatography, of sA1c (%) with a subject who provided a blood sample containing abnormal hemoglobin D, abnormal hemoglobin S or abnormal hemoglobin C by eliminating influences by such abnormal hemoglobin.

Quality control reagents and methods

The present invention provides reagents for instrumentation quality control and methods of use thereof. In particular, sets of peptides or other molecules are provided for evaluating the performance of instruments with mass spectrometry (MS) and/or liquid chromatography (LC) functionalities.