Apparatus and methods for determining a concentration of one or more halogen-containing ions in a sample, including but not limited to: soils, aquifers, groundwater, drinking water, soil, tissue, blood, sewage sludge, compost, and landfill leachate, Particularly, the apparatus and processes are used for the destruction of per- and polyfluoroalkyl substances (PFAS), per- and polyfluorocarbons (PFCs), pesticides, munitions, 1,4-dioxane, pharmaceuticals, microplastics, and others. High destruction efficiencies of these substances is desirable for determination of compliance with government regulations. Apparatus include batch- and continuous-type reactor systems. Processes include supercritical water oxidation (SCWO) and hydrothermal alkaline treatments (HALT).

Systems and methods are provided for analyzing isotopes of a gas from a wellbore to determine geological information associated with the wellbore. A drill device can be used to drill rocks or particles in a wellbore, which can cause a gas to be released within the wellbore. Fluid can be pumped into the wellbore as the drill bit drills the rocks or particles and the fluid, along with the gas released, can flow through the wellbore and to a surface of the wellbore. A gas detector can be positioned near the wellbore for detecting an amount of gas and a type of gas in the fluid and gas mixture and transmitting data about the amount and type of the gas to a computing device. The computing device can output data based on the amount and type of gas in the mixture for determining geological information about the wellbore.

Systems and methods are provided for analyzing isotopes of a gas from a wellbore to determine geological information associated with the wellbore. A drill device can be used to drill rocks or particles in a wellbore, which can cause a gas to be released within the wellbore. Fluid can be pumped into the wellbore as the drill bit drills the rocks or particles and the fluid, along with the gas released, can flow through the wellbore and to a surface of the wellbore. A gas detector can be positioned near the wellbore for detecting an amount of gas and a type of gas in the fluid and gas mixture and transmitting data about the amount and type of the gas to a computing device. The computing device can output data based on the amount and type of gas in the mixture for determining geological information about the wellbore.

The present invention relates to a method of measuring at least one product quality attributes, including critical quality attributes (e.g., oxidation, C-terminal lysine, aggregation, N-terminal glutamine cyclization.) by an online liquid chromatography system, wherein the liquid chromatography system is running a hydrophobic interaction chromatography (HIC) method.

The present invention relates to a method of measuring at least one product quality attributes, including critical quality attributes (e.g., oxidation, C-terminal lysine, aggregation, N-terminal glutamine cyclization.) by an online liquid chromatography system, wherein the liquid chromatography system is running a hydrophobic interaction chromatography (HIC) method.

A temperature control chamber includes a heat impact unit configured for heat impacting a sensor unit in accordance with a heat profile, the sensor unit configured for sensing heat impact response data over time in response to being heat impacted with the heat profile, and a determining unit configured for determining information indicative of a heat transfer characteristic in the temperature control chamber based on the sensed heat impact response data.

A temperature control chamber includes a heat impact unit configured for heat impacting a sensor unit in accordance with a heat profile, the sensor unit configured for sensing heat impact response data over time in response to being heat impacted with the heat profile, and a determining unit configured for determining information indicative of a heat transfer characteristic in the temperature control chamber based on the sensed heat impact response data.

A chromatography column for the use of separation of acidic sugar chains, wherein the column comprises a first column and a second column, the second column connected by a flow path downstream of an outlet of the first column, and selected from the following (1) or (2): (1) the carrier of the first column is hydrophobically modified silica having a group containing a primary amine, a secondary amine or/and a tertiary amine, and the carrier of the second column is a resin having a group containing a primary amine, a secondary amine or/and a tertiary amine; (2) the carrier of the first column is a resin having a group containing a primary amine, a secondary amine or/and a tertiary amine, and the carrier of the second column is hydrophobically modified silica having a group containing a primary amine, a secondary amine, or/and a tertiary amine.

A chromatography column for the use of separation of acidic sugar chains, wherein the column comprises a first column and a second column, the second column connected by a flow path downstream of an outlet of the first column, and selected from the following (1) or (2): (1) the carrier of the first column is hydrophobically modified silica having a group containing a primary amine, a secondary amine or/and a tertiary amine, and the carrier of the second column is a resin having a group containing a primary amine, a secondary amine or/and a tertiary amine; (2) the carrier of the first column is a resin having a group containing a primary amine, a secondary amine or/and a tertiary amine, and the carrier of the second column is hydrophobically modified silica having a group containing a primary amine, a secondary amine, or/and a tertiary amine.

Methods for determining the relative abundance of intact adeno-associated virus (AAV) capsid components in a sample of recombinant AAV particles are disclosed. In embodiments, the methods include a system regeneration process that minimizes or eliminates the presence of ghost peaks to maximize analytical accuracy and ensure product quality and consistency.