A coulter assembly for collecting soil samples from an agricultural field in one embodiment comprises an annular collection blade configured for penetrating soil to capture a sample, an annular cam ring configured for stationary mounting to a frame of an agricultural vehicle and comprising a cam track, a blade hub coupled to the blade for rotatably supporting the annular collection blade from the annular cam ring, and a movable sample collector mounted to the annular collection blade. The moveable sample collector is configured and operable for extracting a soil sample as the annular collection blade is rotated through the soil. The moveable sample collector in one embodiment comprises a piston mechanism including a cylinder and rod movably disposed therein which actuated by the annular cam ring to alternatingly open and close a collection end of the cylinder as the annular collection blade rotates through the soil.

Tissue sample cassettes for receiving tissue samples may include a lower tray, an absorbent substrate, dividers defining elongated compartments over the absorbent substrate, and a cover configured to hold at least one tissue sample in place over the absorbent substrate in at least one corresponding elongated compartment defined by the dividers between the absorbent substrate and the cover. Related systems, devices, and methods are also disclosed.

This document provides devices and methods for an automated tissue grossing system. For example, an automatic tissue grossing system can include an intake system configured to receive a specimen jar containing a tissue sample; a robotic arm comprising a gripper configured to grip the specimen jar; a decapping module comprising a stationary gripper configured to grip the specimen jar and a rotary gripper configured to rotate on a vertical axis and grip a lid of the specimen jar; and a vacuum module comprising an integrated grossing platform, wherein the grossing platform includes a slot sized to receive a cassette from the robotic arm and provide negative pressure through the slot to facilitate tissue transfer from the specimen jar to the cassette.

Methods and systems for automatic spatial and single-cell multi-omics sample preparation and analysis. In examples, a continuous flexible sample strip is dispensed from a strip dispenser assembly, via a rotary mechanism. A prepared biological sample may be mounted to a sample receiving surface of the flexible sample strip to generate a continuous length of prepared sample strip and spatial and single-cell multi-omics data corresponding to the mounted biological sample may be generated based on the continuous length of prepared sample strip. In some embodiments, the methods and systems may be directed to preparing and analyzing a solid phase biological sample, such as an OCT embedded frozen tissue block or a FFPE tissue block. In other embodiments, the methods and systems may be directed to preparing and analyzing a liquid phase biological sample.

Automated systems and methods for the quantitative collection and extraction of a fecal sample, the system including: a primary loading module configured to receive a plurality of primary stool specimen containers, and a secondary loading module configured to receive a plurality of secondary extraction tubes, each with a collection wand; a robotic arm for loading stool on the wand and inserting the stool-loaded wand into the extraction tube; a quality control module configured to assess and confirm whether loading of the collection wand meets a preset acceptable tolerance and if so, assisting with positioning of the robotic arm for accurate insertion of the stool loaded wand into the selected extraction tube; an exhaust module; and executable software loaded into the system and in communication with a database that pairs the primary stool specimen container with a corresponding secondary extraction tube(s).

This document provides devices and methods for an automated tissue grossing system. For example, an automatic tissue grossing system can include an intake system configured to receive a specimen jar containing a tissue sample; a robotic arm comprising a gripper configured to grip the specimen jar; a decapping module comprising a stationary gripper configured to grip the specimen jar and a rotary gripper configured to rotate on a vertical axis and grip a lid of the specimen jar; and a vacuum module comprising an integrated grossing platform, wherein the grossing platform includes a slot sized to receive a cassette from the robotic arm and provide negative pressure through the slot to facilitate tissue transfer from the specimen jar to the cassette.