G01N2035/00356

Apparatus for facilitating chemical analysis based on color principle
11598785 · 2023-03-07 · ·

Disclosed herein is an apparatus for facilitating chemical analysis based on color principle. Accordingly, the apparatus may include a base located at the bottom of the apparatus. Further, the base may be composed of a rectilinear receptacle. Further, the apparatus may include an intermediate plate located above the base. Further, the apparatus may include a hood located atop the intermediate plate. Further, the hood may include a hood rectilinear receptacle. Further, the hood rectilinear receptacle may be secured to the intermediate plate using a fastening mechanism. Further, the apparatus may include a roundtable housed within the hood. Further, the apparatus may include a motion system passing through and engaging with the roundtable and the hood. Further, the apparatus may include an analysis system embedded into at least one board suspended within the base. Further, the analysis system facilitates automated chemical analysis of a plurality of extraneous vials.

Kits And Devices For Detecting Analytes
20230120417 · 2023-04-20 ·

The invention provides devices that improve tests for detecting specific cellular, viral, and molecular targets in clinical, industrial, or environmental samples. The invention permits efficient detection of individual microscopic targets at low magnification for highly sensitive testing. The invention does not require washing steps and thus allows sensitive and specific detection while simplifying manual operation and lowering costs and complexity in automated operation. In short, the invention provides devices that can deliver rapid, accurate, and quantitative, easy-to-use, and cost-effective tests.

SYSTEM AND METHOD FOR AUTOMATED SINGLE CELL PROCESSING

A system and method for automated single cell capture and processing is described, where the system includes a deck supporting and positioning a set of sample processing elements; a gantry for actuating tools for interactions with the set of sample processing elements supported by the deck; and a base supporting various processing subsystems and a control subsystems in communication with the processing subsystems. The system can automatically execute workflows associated with single cell processing, including mRNA capture, cDNA synthesis, protein-associated assays, and library preparation, for next generation sequencing.

Flow analysis method, and flow analysis device
11623218 · 2023-04-11 · ·

The object of the present invention is to provide a novel flow analysis method and a novel flow analyzer each of which makes it possible to improve accuracy of an analysis. A flow analysis method in accordance with an embodiment of the present invention attains the above object by including: a sample introducing step of introducing a sample into a tube (100); a reagent adding step of adding a reagent to the sample which is transferred through the tube (100); and an analyzing step of quantitatively or qualitatively analyzing the sample to which the reagent has been added and further including, after the reagent adding step and before the analyzing step, a gas-liquid separating step of sequentially removing gas which is present in the tube (100).

AUTOMATIC ANALYZER
20230107314 · 2023-04-06 ·

Provided is an automatic analyzer capable of appropriately controlling most of the temperature of an incubator even when local temperature fluctuation occurs.

An automatic analyzer for analyzing a specimen includes an incubator for holding a plurality of vessels that store a mixed liquid of the specimen and a reagent, a heat source for heating or cooling the incubator, a plurality of temperature sensors provided at different positions of the incubator and measuring the temperature, and a control unit for controlling an output of the heat source based on a difference between a target temperature and the highest temperature or the lowest temperature among the measured temperatures of the temperature sensors.

Reaction incubation device, immunity analyzer and reaction incubation method
11619642 · 2023-04-04 · ·

The invention discloses a reaction incubation device, an immunity analyzer and a reaction incubation method. The reaction incubation device comprises a reaction unit (10), which is used for bearing and incubating a reaction container; and a transfer unit (20), which is used for removing the reaction container in and out of the reaction unit (10). The reaction unit (10) comprises a rotating device (11). The rotating device (11) is provided with an incubation position which increases a predetermined angle θ at an interval of fixed time T along with the rotating device (11). The transfer unit (20) removes the reaction container out of the incubation position according to variable incubation time ti. With the device, flexible and variable incubation time can be achieved, and the problem of complicated control, low reliability and that high-speed automation is not easy to achieve in the prior art can be solved.

Integrated sample processing system with variable workflows

One embodiment of the invention is directed to a sample processing system for analyzing a biological sample from a patient. The sample processing system comprises: a plurality of analyzers comprising at least one mass spectrometer, wherein each analyzer in the plurality of analyzers is configured to acquire at least one measurement value corresponding to at least one characteristic of the biological sample; at least one data storage component which stores (i) a list of parameters for the plurality of analyzers, and (ii) at least two condition sets, which contain data associated with completing one or more test orders. The condition sets contain data which differ by at least one variable; and a control system operatively coupled to the plurality of analyzers, and the at least one data storage component. The control system is configured to (i) determine which condition set of the at least two condition sets to use based on the determined condition set, (ii) determine which analyzer or analyzers of the plurality of analyzers to use to process each test order based on the determined condition set and one or more parameters from the list of parameters, and (iii) cause the determined analyzer or analyzers to acquire one or more measurement values for the biological sample.

MAGNETOFLUIDIC CARTRIDGES, DEVICES AND RELATED METHODS OF SAMPLE ANALYSIS

Provided herein are magnetofluidic cartridges of use in a wide variety of sample analysis applications, including nucleic acid amplification assays. The magnetofluidic cartridges include sample inlet wells and sample analysis wells. Temperature sensitive materials are used to separate the sample inlet wells and sample analysis wells from one another prior to performing a given sample analysis application. Related magnetofluidic devices, kits, and methods are also provided.

Integrated consumable data management system and platform

The present invention relates to methods, devices and systems for associating consumable data with an assay consumable used in a biological assay. Provided are assay systems and associated consumables, wherein the assay system adjusts one or more steps of an assay protocol based on consumable data specific for that consumable. Various types of consumable data are described, as well as methods of using such data in the conduct of an assay by an assay system. The present invention also relates to consumables (e.g., kits and reagent containers), software, data deployable bundles, computer-readable media, loading carts, instruments, systems, and methods, for performing automated biological assays.

ROTARY PLATFORM FOR CELL LYSING AND PURIFICATION AND METHOD OF USE

Magnetic beads having cell components of interest are translated between a sequence of processing wells in a tray without need for pipetting. The circular tray contains one or more sequences of wells each interconnected by a respective channel. The tray is rotated about a central axis and a magnet, an agitator, and a heater provided external to the tray enable magnetic bead translation, mixing, and incubation, respectively. The magnet proximate a well forms a cluster of beads. Manipulation of the tray in rotation and elevation results in translation of the cluster from one well, through a channel, and into an adjacent well. The well containing a cluster may be rotationally positioned in front of the agitator, the agitator extended into contact with the well, followed by mechanical agitation. The heater, disposed beneath the tray, may accept a well lowered thereto for selective heating.