Methods and apparatus to mitigate bubble formation in a liquid are disclosed. An example apparatus disclosed herein includes a bottom wall, a first baffle cantilevered from the bottom wall, and a second baffle cantilevered from the bottom wall. The first baffle is spaced apart from the second baffle, and the first baffle and the second baffle are positioned radially relative to an axis of rotation of the apparatus.

The present invention relates to an internal fixing device for an apparatus in a transport mode, an apparatus comprising said device, and a method for reducing the risk of damage to the apparatus during transport. The internal fixing device comprises a limiting device, eccentric roller transmission assemblies, a motor assembly, a motion guide assembly, etc. The two ends of a motor output shaft are fixedly disposed on eccentric roller transmission assemblies on two sides of the apparatus. By triggering a microswitch on the limiting device, eccentric rollers and rocking handles form self locking in a transport mode to stop motion. The present invention can effectively reduce the risk of damage to the apparatus during transport.

The present invention relates to a three-degree-of-freedom library preparation cassette and a method using the same. Two-degree-of-freedom movement capability is provided for mutual positioning between a pipette and reagent wells, within a limited small volume, by combining rotation of a mixing reagent tray and relative horizontal movement between the pipette and the mixing reagent tray, thus greatly increasing the number of reagent wells that can be provided, thereby increasing the functions and applications of the whole system; and the device is simple in structure, low in cost, and suitable for disposable use.

The objective of the present disclosure is to provide a technique for reducing a quantity of magnetic particles remaining on a reaction vessel wall surface in a cleaning step for reducing, in a stepwise manner, an amount of a magnetic particle solution in the reaction vessel. The automated analysis device according to the present disclosure causes an agitating mechanism to operate in such a way that a magnetic substance remaining on the wall surface of the vessel in the previous cleaning step is captured by a cleaning solution in the next cleaning step.

A biological detection system includes a control module, a bearing rotatable plate, a first driving module, rotatable sub-plates, second driving modules, and test cassettes. The bearing rotatable plate has a main rotating shaft. The first driving module is electrically connected to the control module and connected to the main rotating shaft, so that the bearing rotatable plate rotates about the main rotating shaft. The rotatable sub-plates each has a respective independent rotating shaft. The rotatable sub-plates are rotatably disposed on the bearing rotatable plate about the respective independent rotating shaft. The independent rotating shafts and the main rotating shaft may have different rotating directions and rotating speeds. The second driving modules are electrically connected to the control module, so that the rotatable sub-plates independently rotate about the respective independent rotating shaft. The test cassettes are detachably disposed on the rotatable sub-plates, and each of the test cassettes includes a micro-channel structure.

Provided is a biochemical reaction substrate which can achieve higher test sensitivity and shorter testing time in an allergy test, which can also reduce a required amount of blood or the like needed as a specimen and decrease the number of test steps, thereby facilitating performance of the test, and which is to be used in an allergy test in which infection risk of the test staff is reduced. A biochemical reaction substrate, including: a reaction plate; an absorber; a reaction plate storing portion for storing the reaction plate; an absorber storing portion for storing the absorber; a storage container having a heated portion; and a cover assembled to the storage container so as to cover at least a part of the reaction plate and the absorber stored in the storage container, wherein the reaction plate includes a reaction area in which a specific binding substance that specifically reacts with a substance to be tested in a specimen is immobilized, and a flow passage that connects the absorber and the reaction area, and wherein the cover includes an injection hole for injecting a specimen or the like into the reaction plate.

A sample analysis substrate capable of holding a plurality of liquids. The sample analysis substrate has a microchannel structure for transferring a liquid through rotary motion, the sample analysis substrate including: a substrate body having a rotation axis; a first and a second container holding a first and a second liquid therein; a first and a second accommodating section accommodating the first and the second container; and a cap having a first and second projection and movably supported on the substrate body. As the cap moves, the first drive projection and the second drive projection move the first container and the second container with staggered timing, thereby releasing the first and the second liquid accommodated therein.

A method of washing an aspiration probe of an in-vitro diagnostic system is disclosed. The aspiration probe comprises an outer surface and an inner surface forming an inner space for receiving a fluid. The method comprises dipping the aspiration probe into a first wash fluid so that the outer surface is immersed at least in part into the first wash fluid, aspirating an amount of the first wash fluid into the inner space of the aspiration probe, propagating an ultrasonic vibration to the outer surface of the aspiration probe via the first wash fluid, and rinsing the outer surface and the inner surface of the aspiration probe with a second wash fluid. Further, an in-vitro diagnostic method and an in-vitro diagnostic system are disclosed.

The disclosure provides example rinse station apparatus, cartridges, and methods for flow cytometry. The rinse station apparatus includes: (a) a cartridge docking station having a base with a recessed receptacle for a cartridge, a vertical support coupled to the base's first end and a top support coupled to the vertical support and cantilevered over the base, the top support has an opening that aligns with the cartridge's opening, (b) a locking arm coupled to the base's second end, the locking arm's free end has a ridge to cooperate with a detent coupled to the cartridge's rear wall to retain the cartridge in place, (c) a spring coupled to the vertical support's front face to apply force to the cartridge's front wall to bias the cartridge toward the locking arm, and (d) a load cell coupled to the base of the cartridge docking station, the load cell measure's the cartridge's weight.

A method for washing particles includes obtaining an array plate that includes an array of hydrophilic areas surrounded by one or more hydrophobic areas. A respective solution containing a sample is located on a respective hydrophilic area of the array of hydrophilic areas. The respective hydrophilic area includes one or more indentations from a respective surrounding hydrophobic area of the one or more hydrophobic areas. The respective hydrophilic area includes a first indented surface that is offset from a reference surface defined by the respective surrounding hydrophobic area. The method also includes placing an aspirator nozzle above the respective hydrophilic area at a predefined distance from the first indented surface, and aspirating the solution with the aspirator nozzle while the aspirator nozzle is located at the predefined distance from the first indented surface.