The invention herein relates to conducting assays with an apparatus including a substantially transparent assay cartridge loaded with magnetic beads, and a magnets positioned in a platform above and below the assay cartridge. The assay cartridge includes magnetic beads, sample and control solutions in some wells, and assay reagents in others. A microcomputer controls a linear actuator which moves the magnet platform causing the magnetic beads to travel from one well to another and to oscillate within a well. At assay completion, the cartridge will generate a signal representing a test result, which is then sent to a server through a wireless transmission system.

The present disclosure relates to, a magnetic microbeads adsorption mechanism, which is configured to adsorb a magnetic microbeads in a reaction cup and is provided with a cup inlet station and a cup outlet station; the magnetic microbeads adsorption mechanism includes a pedestal, a turntable and multiple magnetic adsorption components; the turntable is rotatably mounted on the pedestal; the turntable can drive the reaction cup to rotate around a central axis of the turntable; the multiple magnetic adsorption components are arranged on a mounting circumference of the pedestal at intervals; the mounting circumference and rotation track of the reaction cup are concentrically arranged; and during a process when the reaction cup rotates from the cup inlet station to the cup outlet station, the adsorption height of the magnetic microbeads relative to cup bottom of the reaction cup can be changed.

The present invention relates to an ELISA-based, liquid-phase immunoassay apparatus optimized for detecting particular ingredients contained in a biological sample, etc., and a method therefor.

A magnetic separator for a liquid handling system includes a base unit having at least one receiver configured to receive a consumable, the at least one receiver being dimensioned to receive the consumable in a predefined location at least partially within the base unit. The magnetic separator further includes a magnet system located within the base unit proximate to the at least one receiver, the magnet system including a first separation magnet configured to perform separation of beads located within the consumable when the first magnet is located proximate to the consumable, and a movement system configured to move the first magnet in at least two directions in order to adapt to a shape of the consumable.

Systems and methods for performing measurements of one or more materials are provided. One system is configured to transfer one or more materials to an imaging volume of a measurement device from one or more storage vessels. Another system is configured to image one or more materials in an imaging volume of a measurement device. An additional system is configured to substantially immobilize one or more materials in an imaging volume of a measurement device. A further system is configured to transfer one or more materials to an imaging volume of a measurement device from one or more storage vessels, to image the one or more materials in the imaging volume, to substantially immobilize the one or more materials in the imaging volume, or some combination thereof.

A method and apparatus for the rapid and reliable preparation of a sample for use in testing for target analytes such as bacteria, viruses, toxins and pathogenic agents in various products. A sample for testing the target analyte is collected from various sources. The method for sample preparation provides for an express process for preparing collected samples for testing. The collected sample may be concentrated by centrifugation, filtration, or other means suitable for sample concentration, homogenized with the addition of a broth and enriched for specified period of time. Immunomagnetic separation of the sample occurs with receptor-coated magnetic microspheres in different test-specific formulations (singleplex or multiplex). An automatic testing system is disclosed which includes a biological testing cassette, in which testing of the sample occurs using liquid crystal diagnostic methodologies.

An apparatus comprising a magnetic assembly and methods for operating the apparatus are provided. The magnetic assembly may be used to manipulate molecules in a liquid preparation, for example to isolate or separate the molecules from the liquid. The magnetic assembly may be used to wash and/or isolate nucleic acid molecules of interest from a liquid preparation.

In blood clotting tests, a reagent is mixed with a sample and a blood clotting reaction is initiated. The time from initiation until the reaction is complete is not fixed. As a result, during analysis, whether or not the blood clotting reaction is complete is judged at fixed intervals based on the measured amount of scattered light. Therefore, time is wasted and analysis cannot be conducted efficiently if the blood clotting reaction reaches completion more quickly than predicted. Accordingly, the automatic analysis device and method takes this problem into consideration. When information about a plurality of samples is entered, the device compares the predicted reaction time length of each requested analysis item for the plurality of samples, determines an analysis sequence to carry out the analysis for each item in order from longest to shortest, and carries out the analysis on the basis of the determined analysis sequence.

The present teachings relate to methods, kits and devices for performing automated sequential nucleic acid isolation and conversion/purification in a single closed system. In various embodiments, the present teaching enable a user to (i) load a device with test samples, reagents and consumables; (ii) select or program the device for the desired nucleic acid isolation and subsequent chemical treatment and/or conversion reaction(s) without further user intervention; and recovering the isolated and treated and/or converted nucleic acid at the conclusion of the program once the device is activated.

A concentrating-enriching magnetic bead purifier includes a base, at least one first mixing sleeve socket, at least one second mixing sleeve socket, and a plurality of wells, and a controlling module. The first mixing sleeve socket includes a first magnetic rod, and a first magnetic rod sleeve. The second mixing sleeve socket includes a second magnetic rod and a second magnetic rod sleeve. A diameter of a cross section of the second magnetic rod sleeve is smaller than that of the first magnetic rod sleeve. The wells include at least one binding well, at least one washing well, and at least one elution well. The volume of the elution well is smaller than that of the binding well. The controlling module controls the first magnetic rod sleeve to only mix or adsorb in the binding well and the washing well and controls the second magnetic rod sleeve to mix or adsorb in the washing well and the elution well.