The present invention discloses a spectral-potentiometric-thermometric multi-dimensional titration analysis instrument, which comprises a spectral titration measurement device, a thermometric titration measurement device and a potentiometric titration measurement device which are arranged in parallel, meets the simultaneous measurement requirements of different analysis methods in chemical analysis, improves the measurement precision of different measurement methods, and effectively reduces the workload of separate experiments. The present invention further provides a usage method of the analysis instrument, provides analysis results of different angles and different characterization parameters for the change process of the material structure in the chemical reaction by conducting comparison analysis on data obtained using different measurement techniques, and effectively reduces the workload of titration analysis.

The present teachings relate to methods, kits and devices for performing automated sequential nucleic acid isolation and conversion/purification in a single closed system. In various embodiments, the present teaching enable a user to (i) load a device with test samples, reagents and consumables; (ii) select or program the device for the desired nucleic acid isolation and subsequent chemical treatment and/or conversion reaction(s) without further user intervention; and recovering the isolated and treated and/or converted nucleic acid at the conclusion of the program once the device is activated.

A method and an analysis system for testing a biological sample, nucleic-acid products being hybridized to capture molecules of a sensor apparatus at different temperatures.

This system takes in raw cellular material collected using a provided swab, blood collection device, urine collection device, or other sample collection device and transforms that biological material into a digital result, identifying the presence, absence and/or quantity of nucleic acids, proteins, and/or other molecules of interest.

The present disclosure relates to a magnetic microbeads adsorption mechanism, which is configured to adsorb a magnetic microbeads in a reaction cup and is provided with a cup inlet station and a cup outlet station; the magnetic microbeads adsorption mechanism includes a pedestal, a turntable and multiple magnetic adsorption components; the turntable is rotatably mounted on the pedestal; the turntable can drive the reaction cup to rotate around a central axis of the turntable; the multiple magnetic adsorption components are arranged on a mounting circumference of the pedestal at intervals; the mounting circumference and rotation track of the reaction cup are concentrically arranged; and during a process when the reaction cup rotates from the cup inlet station to the cup outlet station, the adsorption height of the magnetic microbeads relative to cup bottom of the reaction cup can be changed.

An automatic analysis device and method having a BF separation process, wherein the width in a container conveyance direction of a surface facing a reaction container of a magnet for preliminary magnetic collection of a first magnetic generation part (32p) is set to have a length including a region for housing a liquid sample of the reaction container conveyed to a magnetic collection position of the first magnetic generation part. An end in the container conveyance direction of a surface facing the reaction container of a magnet for regular magnetic collection of a second magnetic generation part (32m) is designed to be close to the center of the region for housing the liquid sample of the reaction container conveyed to a magnetic collection position of the second magnetic generation part.

An automated positive pressure solid phase extraction apparatus and method comprising two tiered lifts devices each individually controllable to individually vertically translate within an elevator framework between a base on which the elevator framework is mounted and a manifold plate supported by the framework in a substantially horizontal plane parallel with and vertically above the two tiered lifts devices and a rectilinearly translating shuttle assembly comprising a shuttle supporting labware for rectilinear travel into and out of the elevator framework to handoff the labware to one of the two tiered elevator lifts or both.

Systems and methods for performing measurements of one or more materials are provided. One system is configured to transfer one or more materials to an imaging volume of a measurement device from one or more storage vessels. Another system is configured to image one or more materials in an imaging volume of a measurement device. An additional system is configured to substantially immobilize one or more materials in an imaging volume of a measurement device. A further system is configured to transfer one or more materials to an imaging volume of a measurement device from one or more storage vessels, to image the one or more materials in the imaging volume, to substantially immobilize the one or more materials in the imaging volume, or some combination thereof.

Fluidic systems including cartridges comprising vessels, microfluidic channels and related methods for performing chemical and/or biological analyses are generally provided. The systems described herein include, according to certain embodiments, a cartridge comprising a vessel adapted and arranged to contain a fluid and/or reagent for performing a chemical and/or biological analysis. The vessel may be designed to have a particular shape or configuration, such as a tapered cross-sectional shape, e.g., to facilitate manipulation of a fluid and/or reagent within the vessel (e.g., a lyosphere).

Systems, methods, devices, and non-transitory media of various embodiments render vector data on static and dynamic surfaces by a computing device for a graphic display or for a separate computing device and/or algorithm to generate an image. Complex vector data associated with a surface for rendering may be rendered. The complex vector data may be decomposed into one or more vector subunits. A geometry corresponding to a volume and a mathematical description of an extrusion of each corresponding vector subunit may be generated. The volume and the mathematical description of the extrusion may intersect a surface level-of-detail of the surface. The geometry may be rasterized as a screen-space decal. Also, a surface depth texture may be compared for the surface against the extrusion using at least the screen-space decal. In addition, geometry batching may be performed for drawing simultaneously a plurality of the one or more vector subunits.