G01N35/1065

Automated nucleic acid processor and automated nucleic acid processing method using multi function dispensing unit
09797008 · 2017-10-24 · ·

In relation to an automated nucleic acid processor and an automated nucleic acid processing method using a multi function dispensing unit, processing involving extraction and amplification of the nucleic acid, can be consistently, quickly and efficiently conducted at a low cost with the use of a multi function dispensing unit, while saving user's trouble without expanding the scale of the device. The multi function dispensing unit includes: a nozzle head provided with a suction-discharge mechanism and nozzles detachably provided with dispensing tips; a container group having, at the very least housing parts for liquids and reaction containers for housing an amplification solution; a transfer mechanism that makes an interval between the nozzles and the container group relatively movable; a temperature controller whereby temperature control of the interior of the reaction vessels is possible; sealing liquids and/or sealing lids that are transportable to the reaction vessels using the nozzles, and which make the amplification solutions housed in the reaction vessels sealable within the reaction vessels; and a sealing control part that controls the suction-discharge mechanism or the transfer mechanism, such that the sealing liquid and/or the sealing lids seal the amplification solution within the reaction vessels when the housing of the amplification solution in the reaction vessels is completed.

Fluid control equipment for bio-reaction, bio-reaction system and fluid control method for bio-reaction

Provided is fluid control equipment for bio-reaction, including a pipette configured to transport a reaction solution, and a liquid pump configured to adjust the internal pressure of the pipette.

AUTOMATIC ANALYZER AND METHOD
20170285054 · 2017-10-05 ·

The present disclosure relates to an automatic analyzer for determining a parameter of a sample fluid, including a dosing device comprising at least one dosing chamber, a first fluid flow path connecting a sample receiving vessel to the dosing chamber via a first pump, a tank containing a dilution medium, a second fluid flow path connecting the tank to the dosing chamber via a second pump, a measuring cell in communication with the dosing chamber via a third fluid flow path via a third pump, and a measuring and control system connected to and configured to control the pumps, wherein the first, second, and third fluid flow paths can selectively be blocked or unblocked by at least one valve unit and the measuring and control system is configured to control the at least one valve unit to block or unblock the first, second, and third flow paths.

Liquid handling device

A liquid handling device that determines a position of a tray utilizing light reflected from structural features of the tray.

Fluidic system for reagent delivery to a flow cell
09777325 · 2017-10-03 · ·

A fluidic system that includes a reagent manifold comprising a plurality of channels configured for fluid communication between a reagent cartridge and an inlet of a flow cell; a plurality of reagent sippers extending downward from ports in the manifold, each of the reagent sippers configured to be placed into a reagent reservoir in a reagent cartridge so that liquid reagent can be drawn from the reagent reservoir into the sipper; at least one valve configured to mediate fluid communication between the reservoirs and the inlet of the flow cell. The reagent manifold can also include cache reservoirs for reagent re-use.

Injector manifold
11243220 · 2022-02-08 · ·

A device and method for purification of information or particles from a sample and provides a device for performing washing steps in automated analyzer systems, the device comprising a multilayer unit with liquid channel and valves. The multilayer unit may comprise three layer.

SYSTEMS, DEVICES, AND METHODS FOR ULTRA-SENSITIVE DETECTION OF MOLECULES OR PARTICLES

Described are systems, devices, and methods which related to various aspects of assays for detecting and/or determining a measure of the concentration of analyte molecules or particles in a sample fluid. In some cases, the systems employ an assay consumable comprising a plurality of assay sites. The systems, devices, and/or methods, in some cases, are automated. In some cases, the systems, devices, and/or methods relate to inserting a plurality of beads into assay sites, sealing assay sites, imaging assay sites, or the like.

MICROORGANISM INOCULATION DEVICE
20220033754 · 2022-02-03 ·

Disclosed is a microorganism inoculation device, which comprises a workbench, wherein support columns are provided on the upper surface of the workbench, a limiting plate is provided in the middle part of the supporting column, an injection head is provided in the middle part of the limiting plate, an air cylinder is provided in the middle part of the lower surface of the workbench, a piston rod of the air cylinder is fixedly connected with the middle part of the upper surface of a lifting plate, guide rods are provided on the upper surface of the lifting plate, the upper end of the guide rod is fixedly connected with a tray, the left and right sides of the upper surface of the tray are fixedly connected with the lower part of a fixed bracket, the middle part of the injection head is slidably connected with the limiting plate.

AUTOMATIC BIOCHEMICAL ANALYZER
20170227560 · 2017-08-10 ·

An automatic biochemical analyzer, comprises a reaction wheel comprising an inner ring and an outer ring, wherein the reaction wheel is equally divided into multiple cuvette positions along a circumferential direction; the inner ring and the outer ring, respectively, each have a photoelectric detection position, a sample injecting position, a reagent injecting position, a sample stirring position, a reagent stirring position, and a cuvette cleaning position; the photoelectric detection position of the inner ring and the photoelectric detection position of the outer ring have a cuvette position interval of N along a counterclockwise or clockwise direction; and the sample injecting positions, the reagent injecting positions, the sample stirring positions, and the reagent stirring positions of the inner ring and the outer ring, respectively, have a cuvette position interval of M along the same direction, M and N being natural numbers, and the difference between M and N being 0 or 1.

Method and apparatus for effecting automated movement of a magnet in an instrument for performing a magnetic separation procedure

Methods, systems, and apparatus are provided for automated isolation of selected analytes, to which magnetically-responsive solid supports are bound, from other components of a sample. An apparatus for performing an automated magnetic separation procedure includes a mechanism for effecting linear movement of a magnet between operative and non-operative positions with respect to a receptacle device. A receptacle holding station within which a receptacle device may be temporarily stored prior to moving the receptacle to the apparatus for performing magnetic separation includes magnets for applying a magnetic field to the receptacle device held therein, thereby drawing at least a portion of the magnetically-responsive solid supports out of suspension before the receptacle device is moved to the magnetic separation station. An automated receptacle transport mechanism moves the receptacle devices between the apparatus for performing magnetic separation and the receptacle holding station.