G01N2201/0415

Eliminating source lamp intensity drift effect using reference measurement between cuvettes

A computer-implemented method for calibrating a photometer in an in-vitro diagnostics analyzer includes generating a cuvette map of a reaction ring identifying a plurality of cuvette locations. The cuvette map is used to identify a plurality of reference measurement areas between the plurality of cuvette locations. A plurality of reference measurements are acquired in the reference measurement areas using the photometer. The photometer is automatically calibrated based on a comparison of the reference measurements to a predetermined standard setup of the photometer.

Inspection machine
11175237 · 2021-11-16 · ·

The automatic inspection machine for containers and contents thereof, comprises a serial horizontal conveyor line of the containers oriented with a vertical axis through at least one inspection station comprising lighting means of the containers, at least one television camera for acquiring images of the illuminated containers, the lighting means comprising a first, a second and at least a third lighting device.

High-speed method and system for inspecting and sorting a stream of unidentified mixed parts

A high-speed method and system for inspecting and sorting a stream of unidentified mixed parts are provided. The system includes a pair of inspection stations each of which includes a vision-based robotic subsystem including a robot configured to pick up a self-supporting part and place the part on a fixtureless rotary stage. A second subsystem optically measures a profile and features of the part during part rotation. A processor is operable to compare the profile and features of the part with the profile and corresponding features of stored templates to identify a matching template. A mechanism including a part sorter directs unidentified parts and parts having an unacceptable geometric dimension or defect to a reject part area and directs identified parts having acceptable geometrical dimensions and no significant defects to good part areas.

Method for measuring optical signal detector performance

A method for measuring optical signal detector performance that includes directing light emitted from an optical signal detector onto a first non-fluorescent surface portion in a first detection zone of the optical signal detector. A first characteristic of light detected by a first sensor of the first optical signal detector is measured while the first non-fluorescent surface portion is in the first detection zone of the optical signal detector. Light emitted from the optical signal detector is directed into a first void in the first detection zone of the optical signal detector. A second characteristic of light detected by the first sensor of the optical signal detector is measured while the first void is in the first detection zone of the optical signal detector. And an operational performance status of the optical signal detector is determined based on at least one of the first characteristic and the second characteristic.

AUTOMATIC ANALYZING DEVICE
20220283080 · 2022-09-08 · ·

An automatic analyzing device according to an embodiment of the present disclosure includes a rotating table, a plurality of light receiving units, and a light radiating unit. The rotating table includes a plurality of placement parts on which a plurality of reaction cuvettes are placed, respectively. The plurality of light receiving units are provided in correspondence with the plurality of placement parts, respectively. The light radiating unit is configured to change from one of the reaction cuvettes to another on which light is radiated, by changing an emission direction of the light.

Analysis device and analysis method

An analysis device includes a turntable holding a substrate, an optical pickup driven in a direction perpendicular to a rotation axis of the turntable and configured to emit laser light to reaction regions and to receive reflected light from the respective reaction regions, an optical pickup drive circuit, and a controller. The reaction regions are formed at positions different from the center of the substrate. The center of the substrate is located on the rotation axis of the turntable. The optical pickup detects a reception level of the reflected light to generate a light reception level signal. The controller controls a turntable drive circuit to rotate the substrate, controls the optical pickup drive circuit to drive the optical pickup, and specifies the respective reaction regions in accordance with a positional information signal and the light reception level signal.

Laser-scatter measurement instrument having carousel-based fluid sample arrangement

An instrument determines a concentration of bacteria in a plurality of fluid samples, and comprises a housing, a rotatable platform, a plurality of fluid containers, a light source, a sensor, and a motor. The rotatable platform is within the housing. The fluid containers are located on the rotatable platform. Each fluid container holds a corresponding one of the plurality of fluid samples, and has an input window and an output window. The light source provides an input beam for transmission into the input windows of the fluid containers and through the corresponding fluid samples. The input beam creates a forward-scatter signal associated with the concentration of bacteria. The motor rotates the rotatable platform so that the input beam sequentially passes through each fluid sample. A sensor within the housing detects the forward-scatter signal exiting from the output window associated with the fluid sample receiving the input beam.

Photometric cuvette mapping

A computer-implemented method for performing photometric cuvette mapping includes detecting edges associated with a plurality of gaps between a plurality of vessels in a reaction ring during a complete rotation of a reaction ring. Each gap is determined according to an edge detection process which includes identifying: a vessel interior in response to detection of a first predetermined number of photometer device control manager (DCM) measurements below a threshold value; a rising edge in response to detection of a second predetermined number of photometer DCM measurements above the threshold value; and identifying a falling edge in response to detection of a third predetermined number of photometer DCM measurements below the threshold value. The edge detection process further includes recording the rising edge and the falling edge as being indicative of one of the plurality of gaps.

METHOD FOR CONTINUOUSLY COLLECTING FLUORESCENCE DATA OF MICROFLUIDIC CHIP

A method for continuously collecting fluorescence data of a microfluidic chip is provided. In the method, an optical path system emits a light perpendicular to the microfluidic chip, such that a center of a light spot formed by the optical path system on the microfluidic chip is located on a circle formed by centers of all reaction cells. The microfluidic chip is rotated around a center of the circle formed by centers of all the reaction cells. Fluorescence signal values are collected by using the optical path system along a rotation direction of the microfluidic chip. The collected fluorescence signal values are processed to obtain effective fluorescence data of all the reaction cells.

OPTICAL POSITIONING CODE DISK, DEVICE AND METHOD FOR MICROFLUIDIC CHIP

An optical positioning code disk, device and method for a microfluidic chip are provided. A cross section of an outer contour of the code disk is circular. N light transmissive openings are arranged uniformly around the code disk. The device includes: the code disk, a positioning pin, a rotating shaft, a motor, an internal photoelectric switch and an external photoelectric switch. A positioning surface is provided on the rotating shaft. The motor is fixedly connected with an end of the rotating shaft, and the other end of the rotating shaft passes through a center of the cross section of the code disk. The internal and external photoelectric switches are configured to identify the light transmissive openings on the code disk.