G01N2201/124

Detection of surface contamination

A device implements a method for detecting contamination of an FTIR-based panel. The apparatus generates projection signals representing detection lines that have propagated on a plurality of propagation paths by total internal reflection (TIR) inside a transmissive panel such that contamination on the panel surface causes attenuation (frustration) of at least one of the projection signals. The device generates a transmission value for each detection line in the transmissive panel, and determines the presence of contamination on the surface of the panel by comparing the transmission values according to at least one of the presented comparison techniques.

MEASUREMENT TIME DISTRIBUTION IN REFERENCING SCHEMES

Methods and systems for measurement time distribution for referencing schemes are disclosed. The disclosed methods and systems can be capable of dynamically changing the measurement time distribution based on the sample signal, reference signal, noise levels, and SNR. The methods and systems can be configured with a plurality of measurement states, including a sample measurement state, reference measurement state, and dark measurement state. In some examples, the measurement time distribution scheme can be based on the operating wavelength, the measurement location at the sampling interface, and/or targeted SNR. Examples of the disclosure further include systems and methods for measuring the different measurement states concurrently. Moreover, the systems and methods can include a high-frequency detector to eliminate or reduce decorrelated noise fluctuations that can lower the SNR.

Automatic analyzer

According to one embodiment, an automatic analyzer comprises a light source, a spectroscope, a photo detection unit, a storage unit, a selection unit, and a calculation unit. The storage unit stores photo detector identifiers related to photo detectors and wavelength band identifiers in association with each other. The selection unit selects a specific photo detector from photo detectors. The specific photo detector corresponds to a specific photo detector identifier associated with a wavelength band identifier of a wavelength band according to a measurement item of a sample. The calculation unit calculates an absorbance related to the measurement item based on a signal from the selected specific photo detector.

Both ultraviolet-visible and double monochromatic fluorescence dual detector for high performance liquid chromatography
09921197 · 2018-03-20 ·

A both ultraviolet-visible and double monochromatic fluorescence dual detector has a small inner-casing, which combines both ultraviolet-visible and double monochromatic fluorescence dual detector widely used in the high performance liquid chromatography by taking the first to use deuterium lamp as the individual light source of the dual detectors, the individual sample detection cell and the individual electrical circuit, the device comprises a detection optical member, which including a first monochromatic spectroscopic deviceraster G1, a second monochromatic spectroscopic deviceraster G2, a light source, four groups of lens needed for processing the light paths; and a detection electromechanical member, which includes: a central controller, a proposed amplifying module, an auto gain module, a noise processing module and a logarithm amplifying module. The dual detector realizes the sensitivity and stability, also the elimination of noise and drift.

Concentration measuring method of optically active substance and concentration measuring device of optically active substance
12158412 · 2024-12-03 · ·

Provided are a concentration measuring method of an optically active substance and a concentration measuring device of an optically active substance, which can easily and accurately measure a concentration of the optically active substance in aqueous humor. The concentration measuring method of an optically active substance includes: a first step of measuring a polarization state of a first reflected light that is obtained by irradiating an aqueous humor in an eye with an incidence light which is polarized and reflecting the incidence light at an interface between the aqueous humor and a lens, in which the polarization state of the first reflected light is measured by irradiating a first incidence light such that an angle between a normal line to a point where the incidence light intersects a surface of the lens, and the incidence light is equal to or smaller than a Brewster angle; a second step of measuring a polarization state of a second reflected light by irradiating with a second incidence light such that an angle of the incidence light is equal to or larger than the Brewster angle; a third step of calculating an optical rotation of the aqueous humor with information on the polarization state of the first reflected light and information on the polarization state of the second reflected light; and a fourth step of calculating a concentration of an optically active substance in the aqueous humor from the optical rotation of the aqueous humor.

Processing apparatus and particle securing method

A processing apparatus includes: a light emission unit configured to emit light to a surface of a particle dispersed liquid applied to a base material, the particle dispersed liquid having particles dispersed in a solvent; a reflected light amount monitoring unit configured to detect an amount of the light reflected, and monitor a temporal variation of the detected value; and a condition adjustment unit configured to adjust a condition for a particle securing process, the particle securing process being performed to remove the solvent and secure the particles onto the base material, wherein, when the temporal variation falls within a predetermined range after the value has reached an extreme value, securing of the particles is determined to have been completed.

METHOD FOR IDENTIFYING A SET OF CANDIDATE SUBSTANCES USING A RAMAN SPECTROSCOPY DEVICE, A RAMAN SPECTROSCOPY DEVICE AND A NON-TRANSITORY COMPUTER-READABLE STORAGE MEDIUM
20250067676 · 2025-02-27 ·

The present inventive concept relates to a method (100) for identifying a set of candidate substances of a sample (10) using a Raman spectroscopy device (200). The method (100) comprises recording (120) a Raman spectrum using an exposure time, and recording (162) a further Raman spectrum using a further exposure time. The further Raman spectrum may exhibit Raman peaks not recorded/detected in the Raman spectrum which possibly reduces the set of candidate substances. If necessary, one or more additional Raman spectra are recorded to further reduce the set of candidate substances, such that a single candidate substance eventually remains, thereby deemed to be a substance of the sample (10). A Raman spectroscopy device (200), a computer program and a non-transitory computer-readable storage medium are also provided

Both Ultraviolet-Visible and Double Monochromatic Fluorescence Dual Detector for High Performance Liquid Chromatography
20170115260 · 2017-04-27 ·

The present invention relates to an innovative analyzing and detecting instrument with excellent sensitivity and stability, especially to a present art that realizes the initiation of the dual-purpose instrument in a small inner-casing which combines both ultraviolet-visible and double monochromatic fluorescence dual detector widely used in the high performance liquid chromatography by taking the first to use deuterium lamp as the individual light source of the dual detectors, the individual sample detection cell and the individual electrical circuit, providing two detectors for detecting and analyzing, and emphasizing the advanced automatic gain art adopted in the present invention to make sure the main technical targets of the whole wavelength range are integral, easy to be checked up, and can solve the existing worldwide technical problem of sensitivity-stability exclusion of the two detectors only with the combination of the double techniques in both automatically eliminating noise and reducing drift, so that the excellent technical performance can be achieved.

DETECTION OF SURFACE CONTAMINATION
20170115235 · 2017-04-27 ·

A device implements a method for detecting contamination of an FTIR-based panel. The apparatus generates projection signals representing detection lines that have propagated on a plurality of propagation paths by total internal reflection (TIR) inside a transmissive panel such that contamination on the panel surface causes attenuation (frustration) of at least one of the projection signals. The device generates a transmission value for each detection line in the transmissive panel, and determines the presence of contamination on the surface of the panel by comparing the transmission values according to at least one of the presented comparison techniques.

MULTI-SPECTRAL GAS ANALYZER SYSTEM WITH MULTIPLE SETS OF SPECTRAL SENSITIVITY

A system and method for multi-spectral gas concentration analysis that includes using a library of multiple sets of optimized spectral sensitivities prepared in advance, and a multi-spectral IR gas analyzer tuned to a set of optimized spectral sensitivity. The multi-spectral IR gas analyzer measures spectral absorption of gas using one or more different sets of optimized spectral sensitivities.