G01N2223/612

TRANSMISSION IMAGING DETECTION DEVICE AND ITS COMPUTERIZED TOMOGRAPHY SYSTEM
20220205932 · 2022-06-30 ·

A transmission imaging detection device (10) is used to collect projection diagrams of measured objects (200) on a conveyor belt (100), comprising X-ray projection imaging devices and laser occlusion sensing devices, the measured objects (200) shifts across the X-ray projection imaging devices and laser occlusion sensing devices on the said conveyor belt (100), and the laser occlusion sensing devices determines whether the measured objects (200) enter the detection segments, the X-ray projection imaging devices collect projection data of the measured objects (200). The transmission imaging detection device (10) combines the translation motion of the measured objects (200) to complete the data acquisition required for real-time CT slice imaging. The computerized tomography system using the above-mentioned transmission imaging detection device (10) ultimately realizes the real-time reconstruction, storage and display of CT slices by bus data transmission and cluster operation.

Information processing apparatus, radiation imaging apparatus, information processing method, and storage medium
11357455 · 2022-06-14 · ·

An information processing apparatus comprises: an obtainment unit configured to obtain a radiation image of a subject; a generation unit configured to generate, based on a plurality of radiation images obtained by radiation of mutually different spectra, a material characteristic image in which a region for each material can be extracted from the interior of the subject; and an image processing unit configured to perform processing of enhancing or attenuating, based on a position of a specific region in the material characteristic image, the specific region in the radiation image.

[18F]-Labeled Benzothiazole Derivative As PET Radiotracer
20220160902 · 2022-05-26 ·

The present disclosure relates to [.sup.18F]-labeled benzothiazole derivatives or salts thereof as positron emission tomography (PET) radiotracers suitable for imaging the stress-signaling non-receptor tyrosine kinase c-abl, and their use in in vivo diagnosis, preclinical and clinical imaging, patient stratification on the basis of mutational status of c-abl and assessing response to therapeutic treatments. The present disclosure further relates to the use of [.sup.18F]-labeled benzothiazole derivatives as PET radiotracers. The disclosure also provides a process for the radiosynthesis of [.sup.18F]-labeled benzothiazole derivatives.

SERIAL SYNCHROTRON CRYSTALLOGRAPHY SAMPLE HOLDING SYSTEM
20220146441 · 2022-05-12 · ·

A fixed target sample holder for serial synchrotron crystallography comprising a goniometer compatible base, a carrier, a sample holding insert which can be placed into the carrier. The sample holding insert comprising fiducials and windows, wherein each of the windows are respectively configured to accept a sample. The windows can also have holes and texture within each window. Additionally, a sample loading workstation for loading crystals into the sample holder and the removal of excess liquid from the sample, comprising a humidity-controlled chamber, a sample support within the chamber, a capture to place the goniometer-compatible base, and a channel in communication with the chamber that allows for the flow of humidified air into the chamber.

X-ray imaging device

The X-ray imaging device (100) is provided with an X-ray source (1), a plurality of gratings, a moving mechanism (8), and an image processing unit (6). The image processing unit (6) is configured to generate a phase-contrast image (16) by associating a pixel value in each pixel of a subject (T) in a plurality of subject images (10) with phase values of a Moire fringe (30) at each pixel and aligning the pixel of the subject of the same position in the plurality of subject images.

BIOLOGICAL IMAGING METHOD USING X-RAY FLUORESCENCE
20220128496 · 2022-04-28 ·

Disclosed herein is a method comprising: causing emission of characteristic X-rays of a first element attached to a first biological analyte; causing emission of characteristic X-rays of a second element attached to a second biological analyte; detecting a characteristic of the first biological analyte based on the characteristic X-rays of the first element and a characteristic of the second biological analyte based on the characteristic X-rays of the second element; wherein the first element and the second element are different; wherein the first biological analyte and the second biological analyte are in the same solution.

Extreme ultraviolet radiation in genomic sequencing and other applications
11718871 · 2023-08-08 ·

Methods, apparatus, and processes which use Extreme ultraviolet radiation (EUV) and/or soft X-ray wavelengths to read, image, edit, locate, identify, map, alter, delete, repair and sequence genes are described. An EUV scanning tool which allows high throughput genomic scanning of DNA, RNA and protein sequences is also described. A database which records characteristic absorption spectra of gene sequences is also described.

In vitro method for detecting active mycobacterium tuberculosis using hair small angle x-ray scattering profile

The present invention relates to an in-vitro method of detecting Mtb infection by using SAXS profile of hair sample. The invention is an approach to overcome the problem of non-invasively and cost-effectively yet reliably diagnosing presence of active tuberculosis in the patient. There would be no risk to the sample handlers getting infected from the sample, cross-contamination of samples, low cost and quick turn-around time of diagnosis.

SINGLE PIECE DROPLET GENERATION AND INJECTION DEVICE FOR SERIAL CRYSTALLOGRAPHY

A single-piece hybrid droplet generator and nozzle component for serial crystallography. The single-piece hybrid droplet generator component including an internally-formed droplet-generation channel, an internally-formed sample channel, a nozzle, and a pair of electrode chambers. The droplet-generation channel extends from a first fluid inlet opening to the nozzle. The sample channel extends from a second fluid inlet opening to the droplet-generation channel and joins the droplet-generation channel at a junction. The nozzle is configured to eject a stream of segmented aqueous droplets in a carrier fluid from the droplet-generation channel through a nozzle opening of the single-piece component. The pair of electrode chambers are positioned adjacent to the droplet-generation channel near the junction between the droplet-generation channel and the sample channel. The timing of sample droplets in the stream of fluid ejected through the nozzle is controlled by applying a triggering signal to electrodes positioned in the electrode chambers of the single-piece component.

X-ray imaging apparatus
11175247 · 2021-11-16 · ·

An X-ray imaging apparatus implements a fluoroscopy that irradiates a weaker dose of X-rays than a dose on the long-length imaging toward a subject M at each location in the long-length imaging range, while moving an X-ray tube in a body axis direction relative to the subject M prior to the long-length imaging, when the long-length imaging is implemented by moving the X-ray tube 2 in the body axis direction relative to the subject M. The dose D.sub.1 at the location having the thick body thickness is less, so that the tube voltage is set up to be high as the tube voltage V.sub.1 and vice versa, the dose D.sub.2 at the location having the thin body thickness is high, so that the tube voltage is set up to be low as the tube voltage V.sub.2.